The Investigations of Nitric Oxide Influence on Lifespan of Fruit Fly D. melanogaster Transgenic Strain dNOS4 [0.03%]
一氧化氮对转基因果蝇dNOS4寿命影响的研究
Mamura Begmanova,Nata Mit,Anara Amirgaliyeva et al.
Mamura Begmanova et al.
Introduction: Aging and longevity control are among the greatest problems in biology and medicine. The fruit fly Drosophila melanogaster is a nice model organism for longevity investigations because of its biological feat...
Oligomeric Amyloid-β Peptide on Sialylic Lewisx-Selectin Bonding at Cerebral Endothelial Surface [0.03%]
寡聚淀粉样蛋白-β肽与脑内皮细胞表面唾液酸Lewisx-选择素结合研究
Sholpan Askarova,Grace Y Sun,Gerald A Meininger et al.
Sholpan Askarova et al.
Introduction: Alzheimer's disease (AD) is a chronic neurodegenerative disorder, which affects approximately 10% of the population aged 65 and 40% of people over the age 80. Currently, AD is on the list of diseases with no...
Sequence Alterations of I(Ks) Potassium Channel Genes in Kazakhstani Patients with Atrial Fibrillation [0.03%]
哈萨克族房颤患者I(Ks)钾通道基因的序列多态性分析
Ainur Akilzhanova,Saule Rakhimova,Zhannur Abilova et al.
Ainur Akilzhanova et al.
Introduction: Atrial fibrillation (AF) is the most common sustained arrhythmia, and it results in significant morbidity and mortality. However, the pathogenesis of AF remains unclear to date. Recently, more pieces of evid...
Ainur Akilzhanova,Ulykbek Kairov,Saule Rakhimova et al.
Ainur Akilzhanova et al.
Introduction: The human genome sequence will underpin human biology and medicine in the next century, providing a single, essential reference to all genetic information. Extraordinary technological advances and decreases ...
Distribution of Beijing Genotype Among Clinical Isolates of M. tuberculosis Circulating in Kazakhstan [0.03%]
在中国新疆流行的结核分枝杆菌临床分离株中北京型的分布状况研究
Ainur Akhmetova,Venera Bismilda,Leila Chingissova et al.
Ainur Akhmetova et al.
Introduction: Methods of genotyping of M. tuberculosis play an important role in tuberculosis (TB) infection control. These techniques are used to detect or exclude laboratory errors, control recurrent cases, and determin...
Collagen Type I alpha1 (COL1A1) Gene Polymorphism and Bone Mineral Density in Postmenopausal Kazakh Women [0.03%]
胶原I型α-1链基因多态性与绝经后哈萨克妇女骨密度的关系研究
Akbota Aitkulova,Ainur Akilzhanova,Zhannur Abilova et al.
Akbota Aitkulova et al.
Introduction: Single nucleotide polymorphism (SNP) at the collagen type I alpha 1 gene (COL1A1) rs1800012 has been widely studied and has shown an association with bone mineral density (BMD) and fractures. A minor allele ...
Transplantation of Cultivated Fibroblasts on a Backing of Xenogenic Tissue in the Treatment of Wounds [0.03%]
异种组织载体移植培养的成纤维细胞治疗创面的研究
Kabylbek Abugaliyev,Ogay Vyacheslav,Danlybayeva Gaziza et al.
Kabylbek Abugaliyev et al.
Introduction: Trophic ulcers are a common health problem, and there are numerous treatment methods. Irreversible damage in the skin, subcutaneous tissue, and fascia with long-term ulcer existence make standard autotranspl...
Influence of Probiotic Consortium on TH1 and TH2 Immune Response [0.03%]
益生菌 consortia 对Th1和Th2免疫反应的影响
Gulnara Shakhabayeva,Almagul Kushugulova,Saule Saduakhasova et al.
Gulnara Shakhabayeva et al.
Introduction: The main role of probiotics is to maintain homeostasis in the intestines and improve bowel protective function. The aim of the present study is to investigate immuno-modulatory effects of a probiotic consort...
Whole genome sequencing of M.tuberculosis in Kazakhstan: preliminary data [0.03%]
哈萨克斯坦结核分枝杆菌全基因组测序:初步数据
Ulykbek Kairov,Ulan Kozhamkulov,Saule Rakhimova et al.
Ulykbek Kairov et al.
Background: Tuberculosis is a major public health problem which infects one third of the world's population, resulting in more than two million deaths every year. The emergence of whole genome sequencing (WGS) technologie...
Shinichi Sunagawa,Siegfried Schloissnig,Manimozhiyan Arumugam et al.
Shinichi Sunagawa et al.
Introduction: The breakthrough of next generation sequencing-technologies has enabled large-scale studies of natural microbial communities and the 16S rRNA genes have been widely used as a phylogenetic marker to study com...