Intra-articular injection of synovium-derived mesenchymal stem cells and hyaluronic acid promote regeneration of massive cartilage defects in rabbits [0.03%]
兔关节内注射滑膜来源的间充质干细胞和透明质酸促进大范围软骨缺损修复
Vyacheslav Ogay,Miras Karzhauov,Ainur Mukhambetova et al.
Vyacheslav Ogay et al.
Introduction: The purpose of this study was to investigate whether intra-articular injection of synovium-derived mesenchymal stem cells (SD MSCs) with low molecular weight hyaluronic acid (HA) could promote regeneration o...
In vivo Biotinylation Based Method for the Study of Protein-Protein Proximity in Eukaryotic Cells [0.03%]
用于研究真核细胞内蛋白质间邻近性的生物素标记方法
Arman Kulyyassov,Erlan Ramanculov,Vasily Ogryzko
Arman Kulyyassov
Introduction: The spatiotemporal order plays an important role in cell functioning and is affected in many pathologies such as cancer and neurodegenerative diseases. One of the ultimate goals of molecular biology is recon...
Vitamin D Receptor Gene Polymorphisms and Breast Cancer Risk in Kazakhstan [0.03%]
哈萨克族维生素D受体基因多态性与乳腺癌发病风险关联研究
Ainur Akilzhanova,Zhannur Abilova,Nurgul Sikhayeva et al.
Ainur Akilzhanova et al.
Introduction: The steroid hormone 1,25-dihydroxyvitamin D3 is thought to protect against breast cancer. The activity of 1,25-dihydroxyvitamin D3 is mediated via the vitamin D receptor (VDR), and a number of polymorphisms ...
Peptidoglycan Hydrolases of Local Lactic Acid Bacteria from Kazakh Traditional Food [0.03%]
源自哈萨克传统食品的乳酸菌肽聚糖水解酶研究
Serik Shaikhin,Asel Moldagulova,Abzal Kazhybayev et al.
Serik Shaikhin et al.
Introduction: Peptidoglycan (PG) is a major component of the cell wall of Gram-positive bacteria and is essential for maintaining the integrity of the bacterial cell and its shape. The bacteria synthesize PG hydrolases, w...
Mauro Magnani
Mauro Magnani
Erythrocytes, also known as Red Blood Cells (RBC), are typically used in transfusion medicine to replace lost blood in patients who underwent different kinds of medical treatments as well as those involved in accidents resulting in blood lo...
Reversibility of cellular aging by reprogramming through an embryonic-like state: a new paradigm for human cell rejuvenation [0.03%]
通过类似胚胎状态的重编程逆转细胞衰老：人类细胞年轻化的新型范式
Jean-Marc Lemaitre
Jean-Marc Lemaitre
Direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a unique opportunity to derive patient-specific stem cells with potential application in autologous tissue replacement therapies and without the ethi...
Elena Zholdybayeva,Aisha Iskakova,Aliya Romanova et al.
Elena Zholdybayeva et al.
Introduction: Pharmacogenomics is an emerging field of medicine that combines genetics and pharmacology. Pharmacogenomic research is relatively new in Kazahkstan, but, in recent years, significant progress has been made i...
Tatyana Kustova,Tatyana Karpenyuk,Alla Goncharova et al.
Tatyana Kustova et al.
Introduction: One of the most serious complications of diabetes is the formation of Diabetic Foot Syndrome. Herbal extracts that combine high antioxidant and antimicrobial properties can be used to treat the resulting neu...
Makhabbat Bekbossynova,Ainur Akilzhanova,Zhannur Abilova et al.
Makhabbat Bekbossynova et al.
Introduction: Cardiac arrhythmias are the most common cause of mortality and sudden cardiac death worldwide. In the past decade, genetic factors underlying arrhythmogenic diseases have been revealed and given novel insigh...
Frequency of NAT2 and GSTP1 polymorphisms in the Kazakh population [0.03%]
Kazakhstan人群NAT2和GSTP1多态性的分布频率分析
Aisha Iskakova,Aliya Romanova,Elena Zholdybayeva et al.
Aisha Iskakova et al.
Introduction: Phase II xenobiotic biotransformation enzymes perform detoxification of hydrophilic and often toxic Phase I products through glutathionetransferase (GST), UDP-glucuronosyltransferase (UDF), N-acetyltransfera...