The intersection of coagulation activation and inflammation after injury: What you need to know [0.03%]
创伤后的凝血激活与炎症：你需要知道的几点问题
Todd W Costantini,Lucy Z Kornblith,Timothy Pritts et al.
Todd W Costantini et al.
Increased platelet mitochondrial function correlates with clot strength in a rodent fracture model [0.03%]
增加的血小板线粒体功能与啮齿动物骨折模型中的凝块强度相关
James Blake Littlejohn,Emily Evans Grenn,Kristen T Carter et al.
James Blake Littlejohn et al.
Background: Thromboelastographic measures of clot strength increase early after injury, portending higher risks for thromboembolic complications during recovery. Understanding the specific role of platelets is challenging...
The risk of hemorrhagic complications after anticoagulation therapy in trauma patients: A multicenter evaluation [0.03%]
创伤患者抗凝治疗后出血并发症的风险：一项多中心评估研究
Cameron Ghafil,Caroline Park,Jeremy Yu et al.
Cameron Ghafil et al.
Background: The use of anticoagulation therapy (ACT) in trauma patients during the postinjury period presents a challenge given the increased risk of hemorrhage. Guidelines regarding whether and when to initiate ACT are l...
SIRT1 downregulation in pneumonia is associated with an immature neutrophil response and increased disease severity [0.03%]
SIRT1在肺炎中的下调与幼稚中性粒细胞反应和疾病加重相关
Hanna E Labiner,Kelli M Sas,Joseph Hoying et al.
Hanna E Labiner et al.
Background: Pneumonia remains a common complication in trauma patients. Sirtuin 1 (SIRT1) is an anti-inflammatory NAD + -dependent deacetylase that has been shown to reduce the severity of ARDS in polymicrobial sepsis. Th...
Intramuscular administration of tranexamic acid in a large swine model of hemorrhage with hyperfibrinolysis [0.03%]
大猪出血伴高纤溶模型肌肉注射氨甲环酸的研究
Christopher J Haberkorn,Carter C Severance,Nathan C Wetmore et al.
Christopher J Haberkorn et al.
Background: Traumatic injury with subsequent hemorrhage is one of the leading causes of mortality among military personnel and civilians alike. Posttraumatic hemorrhage accounts for 40% to 50% of deaths in severe trauma p...
Prostacyclin in trauma patients with hemorrhagic shock: A randomized clinical trial [0.03%]
创伤性出血性休克患者的前列腺素治疗：随机临床试验
Pär I Johansson,Christian Fenger Eriksen,Pernille E Bovbjerg et al.
Pär I Johansson et al.
Background: A main cause of trauma morbidity and mortality is multiple-organ failure, and endotheliopathy has been implicated. Pilot studies indicate that low-dose prostacyclin improves endothelial functionality in critic...
Randomized Controlled Trial
The journal of trauma and acute care surgery. 2024 Mar 1;96(3):476-481. DOI:10.1097/TA.0000000000004150 2024
Is nonoperative management of appendicitis inferior in the COVID-19 era? [0.03%]
新冠肺炎时代急诊阑尾炎的非手术治疗劣效吗？
Emily A Grimsley,Michael P Rogers,Haroon M Janjua et al.
Emily A Grimsley et al.
Background: Previous studies on nonoperative management (NOM) of acute appendicitis (AA) indicated comparable outcomes to surgery, but the effect of COVID-19 infection on appendicitis outcomes remains unknown. Thus, we ev...
Association between transfusion volume and survival outcome following trauma: Insight into the limit of transfusion from an analysis of nationwide trauma registry in Japan [0.03%]
输血量与创伤后生存结果之间的关系：来自日本全国创伤登记的数据分析对输血限度的见解
Keita Shibahashi,Makoto Aoki,Mayu Hikone et al.
Keita Shibahashi et al.
Background: Whether and how the transfusion volume should be limited in resuscitation after trauma remains unclear. We investigated the association between transfusion volume and survival outcome following trauma. ...
Setting an agenda for a national pediatric trauma system: Operationalization of the Pediatric Trauma State Assessment Score [0.03%]
确立国家儿科创伤系统的议程：儿科创伤州评估评分的操作化
Caroline Q Stephens,Mary E Fallat
Caroline Q Stephens
Pediatric trauma system development is essential to public health infrastructure and pediatric health systems. Currently, trauma systems are managed at the state level, with significant variation in consideration of pediatric needs. A recen...
Reply to "REBOA for placenta accreta: An arterial line may be enough" [0.03%]
关于“用于胎盘植入的REBOA：动脉通路可能已足够”的回信
Rachel M Russo,Robert A Cohen
Rachel M Russo