Efficacy of IV Ketamine in Refractory/Super-Refractory Status Epilepticus: A Systematic Review and Meta-Analysis [0.03%]
静脉注射氯胺酮治疗难治性/超级难治性癫痫持续状态的疗效：系统评价和 meta 分析
Abhijit Vijay Lele,Alex Raquer,Jorge Mejia-Mantilla et al.
Abhijit Vijay Lele et al.
Background and objectives: Intravenous ketamine is increasingly used for refractory and super-refractory status epilepticus (RSE/SRSE), yet its efficacy and optimal use remain uncertain. We therefore aimed to synthesize t...
Caplacizumab as an Emerging Treatment for Patients With Thrombotic Thrombocytopenic Purpura Presenting With Acute Ischemic Stroke [0.03%]
克罗拉珠单抗治疗以急性缺血性卒中起病的 thrombotic thrombocytopenic purpura 患者的疗效评估
Konstantinos Melanis,Aikaterini Theodorou,Lina Palaiodimou et al.
Konstantinos Melanis et al.
Objectives: Thrombotic thrombocytopenic purpura (TTP) is rare, life-threatening autoimmune disorder characterized by microvascular thrombosis, severe thrombocytopenia, and hemolytic anemia. It can lead to organ ischemia a...
Biosimilar Therapeutics Substitution: American Academy of Neurology Position Statement [0.03%]
美国神经病学学会关于生物仿制药替换的立场文件
Jonathan D Santoro,Jonathan Crowe,Cale H Coppage et al.
Jonathan D Santoro et al.
Biologic therapeutics have revolutionized treatment of disorders for which there were previously limited options. Biologic products are typically very expensive. However, the emergence of biosimilars (a biologic product that is nearly ident...
Clinically Suspected Neurodegeneration in Histiocytic Neoplasms as Causes of Neurologic Decline: A Retrospective Study [0.03%]
临床怀疑神经退行性变是巨噬细胞活化综合征导致神经系统恶化的原因：一项回顾性研究
Amir Barmada,Ronald S Go,John C Benson et al.
Amir Barmada et al.
Objectives: The aim of this study was to evaluate the causes of suspected neurodegeneration in adults with histiocytic neoplasms. Methods: ...
Efficacy and Safety of VMAT2 Inhibitors in the Treatment of Huntington Disease: A Meta-Analysis of Randomized Clinical Trials [0.03%]
亨廷顿病治疗中VMAT2抑制剂疗效和安全性的 meta 分析：基于随机临床试验的研究
Elder Machado Leite,Armando Leão Lages,José Fernando Barbosa Moura et al.
Elder Machado Leite et al.
Background and objectives: Vesicular monoamine transporter 2 inhibitors (VMAT2is) have demonstrated effectiveness in attenuating motor symptoms of Huntington disease (HD). However, evidence regarding their long-term safet...
Shared Decision-Making Supported by Outcome Information During Discharge Planning of Patients Hospitalized With Stroke [0.03%]
基于结果信息的卒中住院患者出院计划中的共同决策支持
J C M Prick,M V Verschueren,I A Deijle et al.
J C M Prick et al.
Background and objectives: The SHOUT-STROKE study aimed to evaluate the effects of a shared decision-making (SDM) intervention on decision-making, health, and process outcomes during discharge planning of hospitalized pat...
Albendazole-Praziquantel Dual Therapy Compared With Albendazole Monotherapy in Neurocysticercosis: A Systematic Review and Meta-Analysis of RCTs [0.03%]
阿苯达唑单药与阿苯达唑联合氯硝柳胺治疗脑囊尾蚴病的系统评价和 meta 分析
Jorge Resende Gondim Jasmineiro Pitanga,Murilo Marmori Cruccioli,Pedro Henrique Teixeira Carneiro et al.
Jorge Resende Gondim Jasmineiro Pitanga et al.
Background and objectives: Neurocysticercosis is the most common parasitic infection of the CNS and remains a significant, yet often neglected, public health issue in endemic regions. High-quality evidence suggests that a...
Advancing Early Detection of Alzheimer Disease in the Primary Care Setting in the United States [0.03%]
美国初级保健机构阿尔茨海默病早期诊断的推进
Michelle M Mielke,H Ricky Kurzman,Yan Helen Hu et al.
Michelle M Mielke et al.
Background and objectives: As evidence supporting the robustness of blood-based biomarker (BBM) testing for Alzheimer disease (AD) continues to emerge, understanding the perceptions, drivers, and barriers to the adoption ...
Immune Effector Cell-Associated Neurotoxicity Syndrome: A Practical Overview for the General Neurologist [0.03%]
免疫效应细胞相关神经毒性综合征：对普通神经科医师的概述性介绍
Colby Kent Cevering,Hisham Abdel-Azim,Sajad J Khazal et al.
Colby Kent Cevering et al.
Purpose of review: The purpose of this review was to consolidate the clinical, radiographic, and laboratory findings of patients with immune effector cell-associated neurotoxicity syndrome (ICANS) to give physicians a com...
Brain Emergency Management Initiative (BEMI-S): Assessment of Embolectomy Transfer Times Using a Novel Stroke System Transfer Protocol [0.03%]
卒中系统转诊协议下新型取栓转诊时间的评估：BEMI-S计划
Carla N Wood,Dawn M Meyer,Ben Shifflett et al.
Carla N Wood et al.
Background and objectives: Recent studies of national stroke door-in-door-out (DIDO) times found that most transfers for acute interventions are not completed within the recommended time frame. There is a critical need fo...