Paclitaxel in cancer treatment: perspectives and prospects of its delivery challenges [0.03%]
紫杉醇的癌症治疗：其递送挑战的观点和前景
Somnath Singh,Alekha K Dash
Somnath Singh
Paclitaxel (PTX) is a potent anticancer agent whose clinical usefulness is marred by a delivery problem that is caused by its unfavorable pharmacokinetic and physical properties. Paclitaxel is currently formulated in a mixture of Cremophor ...
V R Sinha,M K Agrawal,A Agarwal et al.
V R Sinha et al.
Multiparticulate systems have undergone great development in the past decade fueled by the better understanding of their multiple roles as a suitable delivery system. With the passage of time, significant advances have been made in the proc...
Pramod Mishra,Arvind Gulbake,Aviral Jain et al.
Pramod Mishra et al.
The targeted delivery of chemotherapeutics is essential to minimizing the side effects by sparing the normal tissues by exposure to cytotoxic agents. The various receptors are overexpressed on the surface of the tumor tissues as compared to...
K K Upadhyay,H G Agrawal,C Upadhyay et al.
K K Upadhyay et al.
Drug, gene, and protein delivery is a very challenging and exciting area in nanobiotechnology where block copolymers are increasingly considered especially as carriers for pharmacotherapy of various cancers. Cancer chemotherapy is particula...
Piush Khare,Aviral Jain,Arvind Gulbake et al.
Piush Khare et al.
The accomplishment of selective delivery can be brought through efficient drug targeting in which the attack of drug moiety is visualized only by the diseased organ and not by the organs of the whole body. This, in turn, consequently minimi...