Kayo Harada,Kazuhiko Ikeda,Hayato Matsumoto et al.
Kayo Harada et al.
Chronic lymphocytic leukemia (CLL) rarely exhibits an aggressive clinical course and its patients often have chromosomal deletions or additions. Furthermore, reciprocal translocations are barely observed in CLL. There have only been a few r...
Comparison of safety and toxicity of liposomal doxorubicin vs. conventional anthracyclines: a meta-analysis [0.03%]
脂质体多柔比星与传统蒽环类药物安全性及毒性的比较：meta分析
Shamudheen M Rafiyath,Mohammad Rasul,Byung Lee et al.
Shamudheen M Rafiyath et al.
Background: Liposomal formulations of anthracyclines appear to have favorable toxicity profile when compared with conventional anthracyclines in elderly, high risk cardiac patients and patients with prior use of anthracyc...
Publish, not perish: Introducing Experimental Hematology & Oncology [0.03%]
发表，不失落：Experimental Hematology & Oncology期刊介绍
Zihai Li,Chung-Tsen Hsueh,Delong Liu
Zihai Li
As a scientific discipline, medicine can only be advanced by experimentation. Experimentation could either validate or refute a hypothesis. Unfortunately, today's publication climate strongly favors publication of positive research findings...
Thalidomide and its analogues in the treatment of Multiple Myeloma [0.03%]
治疗多发性骨髓瘤的thalidomide及其类似物
Tahir Latif,Nabeel Chauhan,Rashid Khan et al.
Tahir Latif et al.
Multiple myeloma is an incurable malignant disorder of mature B-cells that predominantly affects the elderly. The immunomodulatory drug (IMiD) thalidomide and its newer analogs demonstrate increased antitumor activity, and have had a positi...
Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation [0.03%]
补体抑制剂依库珠单抗治疗凝血抑制治疗无效的阵发性夜间血红蛋白尿症合并毕肖普法布里西综合征患者
Andrés Brodsky,Octavio Mazzocchi,Fabiana Sánchez et al.
Andrés Brodsky et al.
Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive, life-threatening disorder characterized by chronic intravascular hemolysis caused by uncontrolled complement activation. Hepatic vein thrombosis (Budd-Chiari syndrome) is common in...
Bridging therapy with histotripsy prior to liver transplantation for hepatocellular carcinoma: a first case report [0.03%]
肝细胞癌肝脏移植前运用组织爆破过渡治疗一例报告
Background: Histotripsy is a novel, non-invasive, non-ionizing, and non-thermal ablation technique that disrupts tumors using acoustic cavitation. We report the first use of Histotripsy as bridging therapy prior to liver ...
Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction [0.03%]
用于改善肿瘤内T细胞低功能的经工程改造的溶瘤病毒，表面包裹了抗PD-1和阿仑膦酸盐
Background: Glioblastoma is a highly aggressive and devastating primary brain tumor that is resistant to conventional therapies. Oncolytic viruses represent a promising therapeutic approach for glioblastoma by selectively...