Dazhong Xu,Qi Wang,Yongping Jiang et al.
Dazhong Xu et al.
Angiogenesis is essential for promoting growth and metastasis of solid tumors by ensuring blood supply to the tumor mass. Targeting angiogenesis is therefore an attractive approach to therapeutic intervention of cancer. Tumor angiogenesis i...
Hosam A Elbaz,Todd A Stueckle,William Tse et al.
Hosam A Elbaz et al.
A growing body of evidence indicates that digitoxin cardiac glycoside is a promising anticancer agent when used at therapeutic concentrations. Digitoxin has a prolonged half-life and a well-established clinical profile. New scientific avenu...
Response of hemorrhagic bullous skin lesions of the breast secondary to primary systemic amyloidosis to a five-drug combination chemotherapy: a case report and review of the literature [0.03%]
原发性全身性淀粉样变性继发的乳房出血性大疱性皮肤损害对五联化疗的反应：病例报告及文献复习
Aref Agheli,Marvin Becker,Gary Becker et al.
Aref Agheli et al.
Two major types of amyloidosis are primary amyloidosis or amyloid light chain amyloidosis and secondary amyloidosis. Although amyloidosis involves a variety of organ systems including skin, the occurrence of bullous skin lesions is rare. Li...
CD19: a biomarker for B cell development, lymphoma diagnosis and therapy [0.03%]
CD19：B细胞发育、淋巴瘤诊断和治疗的生物标志物
Kemeng Wang,Guoqing Wei,Delong Liu
Kemeng Wang
The human CD19 antigen is a 95 kd transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD19 is classified as a type I transmembrane protein, with a single transmembrane domain, a cytoplasmic C-terminus, and extracellular ...
Clinical significance of E2F1 protein expression in non-small cell lung cancer [0.03%]
E2F1蛋白在非小细胞肺癌的表达及临床意义分析
Jung-Jyh Hung,Chung-Tsen Hsueh,Kuan-Hua Chen et al.
Jung-Jyh Hung et al.
Background: The transcription factor E2F1 has been implicated in cell cycle control and DNA damage response. Paradoxically, E2F1 can promote apoptosis and function as tumor suppressor. In non-small cell lung cancer (NSCLC...
Impact of tandem autologous stem cell transplantation and response to transplant in the outcome of multiple myeloma [0.03%]
串联自体干细胞移植及其对移植反应在多发性骨髓瘤预后中的影响
Rui Bergantim,Fernanda Trigo,José E Guimarães
Rui Bergantim
Background: Multiple Myeloma (MM) is the commonest indication for autologous stem cell transplantation (ASCT). Methods: We retrospectiv...
Long lasting complete molecular remission after suspending dasatinib treatment in chronic myeloid leukemia [0.03%]
尼洛替尼停药后的慢性髓性白血病患者的分子生物学缓解状态评估
Klára Gadó,András Matolcsy,Judit Csomor et al.
Klára Gadó et al.
Tyrosine kinase inhibitors specific for BCR-ABL, were a major breakthrough in CML therapy. Second generation tyrosine kinase inhibitors (dasatinib, nilotinib) are indicated for imatinib resistant and intolerant patients. Present guidelines ...
Pattern of antigen expression in metastases after radioimmunotherapy of a syngeneic rat colon carcinoma utilizing the BR96 antibody [0.03%]
BR96抗体放射免疫治疗同基因大鼠结肠癌后转移灶抗原表达模式
Erika Elgström,Sophie E Eriksson,Tomas G Ohlsson et al.
Erika Elgström et al.
Background: Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression...
Isolated cardiac metastasis from plasmacytoid urothelial carcinoma of the bladder [0.03%]
孤立性心脏浆细胞样尿路上皮膀胱癌转移病灶
Joshua R Peck,Charles L Hitchcock,Sara Maguire et al.
Joshua R Peck et al.
A 57-year-old male with a history of hypertension presented with shortness of breath, intermittent substernal chest pain, subjective fevers, and a 30-pound weight loss. He was found to have a bladder mass four months prior to presentation, ...
Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR) [0.03%]
应用扩增子融合位点聚合酶链反应（AFS-PCR）对急性淋巴细胞白血病（ALL）中微量残留病变（MRD）进行量化检测的研究
Axel Weber,Sylvia Taube,Udo Zur Stadt et al.
Axel Weber et al.
The amplification of putative oncogenes is a common finding within the genome of various cancer types. Identification and further targeting of specific junction sites within the sequence of genomic amplicons (amplicon fusion sites, AFS) by ...