Impact of tandem autologous stem cell transplantation and response to transplant in the outcome of multiple myeloma [0.03%]
串联自体干细胞移植及其对移植反应在多发性骨髓瘤预后中的影响
Rui Bergantim,Fernanda Trigo,José E Guimarães
Rui Bergantim
Background: Multiple Myeloma (MM) is the commonest indication for autologous stem cell transplantation (ASCT). Methods: We retrospectiv...
Long lasting complete molecular remission after suspending dasatinib treatment in chronic myeloid leukemia [0.03%]
尼洛替尼停药后的慢性髓性白血病患者的分子生物学缓解状态评估
Klára Gadó,András Matolcsy,Judit Csomor et al.
Klára Gadó et al.
Tyrosine kinase inhibitors specific for BCR-ABL, were a major breakthrough in CML therapy. Second generation tyrosine kinase inhibitors (dasatinib, nilotinib) are indicated for imatinib resistant and intolerant patients. Present guidelines ...
Pattern of antigen expression in metastases after radioimmunotherapy of a syngeneic rat colon carcinoma utilizing the BR96 antibody [0.03%]
BR96抗体放射免疫治疗同基因大鼠结肠癌后转移灶抗原表达模式
Erika Elgström,Sophie E Eriksson,Tomas G Ohlsson et al.
Erika Elgström et al.
Background: Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression...
Isolated cardiac metastasis from plasmacytoid urothelial carcinoma of the bladder [0.03%]
孤立性心脏浆细胞样尿路上皮膀胱癌转移病灶
Joshua R Peck,Charles L Hitchcock,Sara Maguire et al.
Joshua R Peck et al.
A 57-year-old male with a history of hypertension presented with shortness of breath, intermittent substernal chest pain, subjective fevers, and a 30-pound weight loss. He was found to have a bladder mass four months prior to presentation, ...
Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR) [0.03%]
应用扩增子融合位点聚合酶链反应（AFS-PCR）对急性淋巴细胞白血病（ALL）中微量残留病变（MRD）进行量化检测的研究
Axel Weber,Sylvia Taube,Udo Zur Stadt et al.
Axel Weber et al.
The amplification of putative oncogenes is a common finding within the genome of various cancer types. Identification and further targeting of specific junction sites within the sequence of genomic amplicons (amplicon fusion sites, AFS) by ...
JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines [0.03%]
JAK2V617F和p53突变同时存在于红白血病和巨核细胞白血病细胞系中
Wanke Zhao,Yanhong Du,Wanting Tina Ho et al.
Wanke Zhao et al.
Background: JAK2V617F, a gain-of-function mutant form of tyrosine kinase JAK2, is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs), a group of chronic hematological diseases that often lead t...
Treatment of splenic marginal zone lymphoma of the CNS with high-dose therapy and allogeneic stem cell transplantation [0.03%]
高强度治疗及异基因干细胞移植治疗中枢神经系统脾边缘区淋巴瘤
Christoph Busemann,Andrej Gudzuhn,Carsten Hirt et al.
Christoph Busemann et al.
Therapy of indolent lymphomas with involvement of the central nervous system (CNS) has not been standardized so far. A 42-year old male patient presented with neurological signs because of leukemic splenic marginal zone lymphoma (SMZL) mani...
Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier [0.03%]
放射治疗与BRCA1突变携带者管腔上皮细胞优先耗竭的关联研究
Huai-Chin Chiang,Sreejith J Nair,I-Tien Yeh et al.
Huai-Chin Chiang et al.
Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of B...
Current management and prognostic features for gastrointestinal stromal tumor (GIST) [0.03%]
胃肠间质瘤(GIST)的当前管理及预后指标特征分析
Gurpreet Lamba,Ridhi Gupta,Byung Lee et al.
Gurpreet Lamba et al.
Stromal or mesenchymal neoplasms affecting the gastrointestinal (GI) tract have undergone a remarkable evolution in how they are perceived, classified, approached, diagnosed and managed over the last 30 years. Gastrointestinal stromal tumor...
R-CHOP with dose-attenuated radiation therapy could induce good prognosis in gastric diffuse large B cell lymphoma [0.03%]
剂量减小的放疗联合R-CHOP方案可使胃弥漫大B细胞淋巴瘤患者获得良好预后
Yuko Mishima,Yasuhito Terui,Masahiro Yokoyama et al.
Yuko Mishima et al.
Background: The treatment strategy for gastric diffuse large cell lymphoma (DLBCL) has not been standardized in such as to the cycles of chemotherapy, dose of radiation, or necessity for the surgery. Although the results ...