Satoshi Ichikawa,Yasuaki Watanabe,Kei Saito et al.
Satoshi Ichikawa et al.
T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare subtype of diffuse large B-cell lymphoma, and has been reported to mainly affect lymph nodes with advanced Ann Arbor stage. We present a 69-year-old woman with a past history ...
French "real life" experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia [0.03%]
克罗法滨治疗难治或复发急性淋巴细胞白血病患儿的法国真实世界经验
Pascale Trioche,Brigitte Nelken,Gérard Michel et al.
Pascale Trioche et al.
Background: Clofarabine alone or in combination with cyclophosphamide and etoposide has shown a good efficacy and a tolerable toxicity profile in previous studies of children with relapsed or refractory leukaemia. This re...
Lily Weiß,Thomas Efferth
Lily Weiß
Polo-like kinase 1 (Plk1) is an interesting molecule both as a biomarker and as a target for highly specific cancer therapy for several reasons. Firstly, it is over-expressed in many cancers and can serve as a biomarker to monitor treatment...
Intravascular CNS lymphoma: Successful therapy using high-dose methotrexate-based polychemotherapy [0.03%]
中枢神经系统血管内淋巴瘤的治疗取得成功
Sied Kebir,Klaus Kuchelmeister,Pitt Niehusmann et al.
Sied Kebir et al.
Intravascular diffuse large B-cell lymphoma limited to the CNS (cIVL) is a very rare malignant disorder characterized by a selective accumulation of neoplastic lymphocytes (usually B cells) within the lumen of CNS blood vessels but not in t...
BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation [0.03%]
BIRC6(APOLLON)在急性髓系白血病中表达下降并可抑制中性粒细胞分化
Anna M Schläfli,Bruce E Torbett,Martin F Fey et al.
Anna M Schläfli et al.
Background: Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP BIRC6 is associated with unfavorable clinica...
Hyperphosphatemia during spontaneous tumor lysis syndrome culminate in severe hypophosphatemia at the time of blast crisis of Phneg CML to acute myelomoncytic leukemia [0.03%]
SPTLS导致的高磷血症在Ph阳性CML转变成急性单核细胞白血病的变急期达到严重的低磷血症
Ophira Salomon,Eli J Holtzman,Pazit Beckerman et al.
Ophira Salomon et al.
Extreme swing of phosphor from severe hyperphosphatemia to severe hypophosphatemia in a patient with blast crisis of myeloid origin was the result of imbalance between massive apoptosis of leukemic cells in the context of spontaneous tumor ...
Numerical analysis of airflow alteration in central airways following tracheobronchial stent placement [0.03%]
气管支气管支架置入后中央大气道气流改变的数值分析
Chien-Yi Ho,Hsiu-Mei Liao,Chih-Yen Tu et al.
Chien-Yi Ho et al.
The computational fluid dynamics method, which provides an estimation of the pressure drop in the airway before and after the stent implantation, is proposed in this study. This method is based on the finite volume model. The pressure field...
Ratio of involved/uninvolved immunoglobulin quantification by Hevylite™ assay: clinical and prognostic impact in multiple myeloma [0.03%]
Hevylite检测方法中治疗相关与非相关的免疫球蛋白比值的临床意义及预后价值在多发性骨髓瘤中的作用
Efstathios Koulieris,Panayiotis Panayiotidis,Stephen J Harding et al.
Efstathios Koulieris et al.
Background: HevyLite™ is a new, recently developed method that facilitates separate quantification of the kappa- and lambda-bounded amounts of a given immunoglobulin (Ig). Using this method, we measured intact immunoglob...
Xin Huang,Xin Du,Yangqiu Li
Xin Huang
The B-cell leukemia/lymphoma 11B (BCL11B) gene is a member of the BCL family which plays a crucial role in the development, proliferation, differentiation and subsequent survival of T cells. BCL11B gene alterations are related to malignant ...
Hypoglycemia associated with L-asparaginase in acute lymphoblastic leukemia treatment: a case report [0.03%]
儿童急性淋巴细胞白血病化疗期间低血糖发作一例报告
Ryuma Tanaka,Tomoo Osumi,Masashi Miharu et al.
Ryuma Tanaka et al.
A patient with acute lymphoblastic leukemia repeatedly developed hypoglycemia during chemotherapy. Comparison of serum glucose trends between chemotherapy with and without L-asparaginase (L-Asp) demonstrated a strong association between L-A...