The effect of metronomic versus standard chemotherapy on the regulatory to effector T-cell equilibrium in cancer patients [0.03%]
/meta>代谢化疗与常规化疗对癌症患者调节性T细胞和效应T细胞平衡影响的比较(meta)
Anna Koumarianou,Maria-Ioanna Christodoulou,Pavlos Patapis et al.
Anna Koumarianou et al.
Background: The host's immune system is crucially involved in cancer development and progression. The ratio of regulatory to effector T-cells, as well as the interplay of T-cells with therapeutic agents, impact on cancer ...
Fei-Yu Niu,Yi-Long Wu
Fei-Yu Niu
Since the recognition of epidermal growth factor receptor (EGFR) as a therapeutic target, EGFR tyrosine kinase inhibitors (TKIs) have been used in lung cancer patients with EGFR mutations, which has been a major breakthrough for lung cancer...
Demographic, clinical, pathological, molecular, treatment characteristics and outcomes of nonmetastatic inflammatory breast cancer in Morocco: 2007 and 2008 [0.03%]
摩洛哥非转移性炎性乳腺癌的发病特征、临床病理学、分子、治疗及转归：2007年和2008年数据
Nabil Ismaili,Hind Elyaakoubi,Youssef Bensouda et al.
Nabil Ismaili et al.
We analyze the epidemiological characteristics and outcomes of 72 patients diagnosed with non-metastatic inflammatory breast cancer (IBC) at National Institute of Oncology of Rabat in Morocco, between January 2007 and December 2008. IBC pat...
Zihai Li,Lieping Chen,Mark P Rubinstein
Zihai Li
The immune system is the built-in host defense mechanism against infectious agents as well as cancer. Protective immunity against cancer was convincingly demonstrated in the 1940s with syngeneic animal models (JNCI 18:769-778, 1976; Cancer ...
Everolimus and sunitinib for advanced pancreatic neuroendocrine tumors: a matching-adjusted indirect comparison [0.03%]
依维莫司与舒尼替尼治疗晚期胰腺神经内分泌肿瘤的匹配调整间接比较研究
James Signorovitch,Elyse Swallow,Evan Kantor et al.
James Signorovitch et al.
Background: Everolimus and sunitinib have been approved for the treatment advanced pancreatic neuroendocrine tumors, but have not been compared to each other in a randomized trial and have not demonstrated prolonged overa...
ABC transporter activity linked to radiation resistance and molecular subtype in pediatric medulloblastoma [0.03%]
儿童髓母细胞瘤中与放射抵抗及分子亚型相关的ABC转运蛋白活性
Wendy J Ingram,Lisa M Crowther,Erica B Little et al.
Wendy J Ingram et al.
Background: Resistance to radiation treatment remains a major clinical problem for patients with brain cancer. Medulloblastoma is the most common malignant brain tumor of childhood, and occurs in the cerebellum. Though ra...
Lawrence B Afrin
Lawrence B Afrin
Mast cell activation syndrome (MCAS) is a relatively recently recognized cause of chronic multisystem polymorbidity of a generally inflammatory theme. Patients with MCAS often report migratory soft tissue and/or bone pain which frequently r...
Evaluation of serum Amphiregulin levels in breast cancer patients and cancer-free controls [0.03%]
评估乳腺癌患者和非癌症对照组血清Amphiregulin水平的效果
Esther A Peterson,Eirini Pectasides,Shabana Shabbeer et al.
Esther A Peterson et al.
Background: Expression of the Epidermal Growth Factor Receptor ligand, Amphiregulin, has been associated with estrogen receptor positive breast cancer. As Amphiregulin is proteolytically released from the surface of breas...
Impressive thrombocytosis evolving in a patient with a BCR-ABL positive CML in major molecular response during dasatinib treatment unmasks an additional JAK2V617F [0.03%]
一项接受达沙替尼治疗的BCR-ABL阳性CML患者在主要分子学反应期出现令人惊讶的血小板增多症，从而掩盖了JAK2V617F附加突变的存在
Friederike Pastore,Stephanie Schneider,Oliver Christ et al.
Friederike Pastore et al.
We present a case of a 42-year old female with the rare diagnosis of a myeloproliferative syndrome harboring both a BCR-ABL transclocation and a JAK2V617F mutation.Initially diagnosed with a CML, the patient underwent treatment with imatini...
Hairy cell leukemia in kidney transplantation: lesson from a rare disorder [0.03%]
罕见病毛细胞白血病在肾移植中的教训
Fabrizio Vinante,Paola Tomei,Gianluigi Zaza et al.
Fabrizio Vinante et al.
We report here on the diagnosis and successful treatment of a case of hairy cell leukemia (HCL) that arose 15 years after kidney transplantation in a 51-year-old patient. As soon as the diagnosis was made, HCL was treated with 2-CDA, obtain...