Levodopa Responsiveness in Adult-onset Lower Limb Dystonia is Associated with the Development of Parkinson's Disease [0.03%]
成年期起病的下肢肌张力异常对左旋多巴的反应与帕金森病的发生发展有关
Florence C F Chang,Keith A Josephs
Florence C F Chang
Background: Adult-onset primary lower limb dystonia (AOPLLD) has been reported as an early sign of Parkinson's disease (PD) or Parkinson-plus syndrome in case series. No prior systematic analysis has assessed clinical clu...
Primary dystonia: conceptualizing the disorder through a structural brain imaging lens [0.03%]
原发性扭转痉挛：从结构脑影像角度重新认识该疾病
Ritesh A Ramdhani,Kristina Simonyan
Ritesh A Ramdhani
Background: Dystonia is a hyperkinetic movement disorder characterized by involuntary, repetitive twisting movements. The anatomical structures and pathways implicated in its pathogenesis and their relationships to the ne...
Efficacy and Safety of IncobotulinumtoxinA in Subjects Previously Treated with Botulinum Toxin Versus Toxin-Naïve Subjects with Cervical Dystonia [0.03%]
颈部痉挛病以往使用过肉毒毒素治疗与未经肉毒毒素治疗的患者中注射INCobotulinumtoxinA的有效性和安全性
Hubert H Fernandez,Eric J Pappert,Cynthia L Comella et al.
Hubert H Fernandez et al.
Background: To determine whether botulinum toxin treatment history affected the outcomes of a study comparing the safety and efficacy of incobotulinumtoxinA with placebo in subjects with cervical dystonia (CD). ...
Sophie M Coffeng,Jorrit I Hoff,Selma C Tromp
Sophie M Coffeng
Background: Orthostatic tremor (OT) is a high-frequency tremor (13-18 Hz) present in the legs when standing. Underlying disease is found in one-third of OT patients. ...
Middle ear myoclonus: two informative cases and a systematic discussion of myogenic tinnitus [0.03%]
中耳肌阵挛：两例有教育意义的病例和肌源性耳鸣的系统讨论
Aviva Ellenstein,Nadia Yusuf,Mark Hallett
Aviva Ellenstein
Background: The term middle ear myoclonus (mem) has been invoked to explain symptoms of tinnitus presumably caused by the dysfunctional movement of either of the two muscles that insert in the middle ear: tensor tympani a...
Shell shock: Psychogenic gait and other movement disorders-A film review [0.03%]
浅论心因性步态及其他运动障碍——影片评论
Mariana Moscovich,Danny Estupinan,Muhammad Qureshi et al.
Mariana Moscovich et al.
Background: The psychological pressure on soldiers during World War I (WWI) and other military conflicts has resulted in many reported cases of psychogenic gait as well as other movement disorders. In this paper, psychoge...
Hortensia Gimeno,Sinead Barry,Jean-Pierre Lin et al.
Hortensia Gimeno et al.
Background: Sydenham's chorea (SC) is the most common type of acquired chorea in childhood. In some cases, symptoms (most commonly described in terms of neurological signs) last up to 2 years, and many cases relapse. This...
REM Sleep Behavior Disorder and Prodromal Neurodegeneration - Where Are We Headed? [0.03%]
REM睡眠行为障碍和 prodromal神经退行性疾病-我们接下来的研究方向是什么？
Ronald B Postuma,Jean-Francois Gagnon,Jacques Y Montplaisir
Ronald B Postuma
Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by loss of normal atonia during REM sleep, such that patients appear to act out their dreams. The most important implication of research into this area is that patients...
Rebecca Wolf Gilbert
Rebecca Wolf Gilbert
Background: A sensory trick, or geste antagoniste, is defined as a physical gesture (such as a touch on a particular body part) that mitigates the production of an involuntary movement. This phenomenon is most commonly de...
Adult-onset Idiopathic Focal Lower Extremity Dystonia: A Rare Task-Specific Dystonia [0.03%]
成人发作的原发性下肢局限性肌张力障碍：一种罕见的任务特异性肌张力障碍
Ritesh A Ramdhani,Steven J Frucht
Ritesh A Ramdhani
Background: Adult-onset focal lower extremity (LE) dystonia is rare, but there have recently been a number of case series that have reported an idiopathic variant triggered during ambulation. ...