Therapeutic potential of human umbilical cord derived mesenchymal stem cells on rat model of liver fibrosis [0.03%]
人脐带间充质干细胞对肝纤维化大鼠的治疗作用研究
Mona Farouk Mansour,Sahar Mansour Greish,Ahmed Taher El-Serafi et al.
Mona Farouk Mansour et al.
End-stage liver disease is a worldwide cause of morbidity and mortality, which is associated with a considerable economic burden. As the disease progresses, fibrosis will replace the hepatic architecture and compromise liver functions. The ...
Li Wang,Yuan Liu
Li Wang
Cerebellar granule cells originate from precursors located at the dorsal region of rhombomere in the hindbrain of embryos. They undergo proliferation from embryo to post-natal period so as to form the major cell type of the cerebellum. The ...
Impact of donor characteristics on the quality of bone marrow as a source of mesenchymal stromal cells [0.03%]
供者特性对骨髓间充质基质细胞质量的影响
Emilia Barreto-Durán,Claudia Camila Mejía-Cruz,Efrain Leal-García et al.
Emilia Barreto-Durán et al.
In recent years, the therapeutic use of mesenchymal stromal cells (MSC) has generated a valuable number of scientific studies that delve into their biological characteristics and their potential in regenerative medicine; however, the impact...
Current approaches in regenerative medicine for the treatment of diabetes: introducing CRISPR/CAS9 technology and the case for non-embryonic stem cell therapy [0.03%]
糖尿病再生医学的当前方法：引入CRISPR/CAS9技术及应用非胚胎干细胞疗法的必要性
Lauren Coombe,Aamir Kadri,Jessica Ferrer Martinez et al.
Lauren Coombe et al.
Type 1 diabetes mellitus (T1DM) is an autoimmune disorder in which the body destroys its pancreatic β cells. Since these cells are responsible for insulin production, dysfunction or destruction of these cells necessitates blood glucose con...
Therapeutic applications of adipose-derived stem cells in cardiovascular disease [0.03%]
脂肪来源干细胞在心血管疾病治疗中的应用
Kyle Bruun,Erika Schermer,Anjali Sivendra et al.
Kyle Bruun et al.
Cardiovascular disease (CVD) is the number one cause of death globally, and new therapeutic techniques outside of traditional pharmaceutical and surgical interventions are currently being developed. At the forefront is stem cell-centered th...
A review of clinical trials: mesenchymal stem cell transplant therapy in type 1 and type 2 diabetes mellitus [0.03%]
间充质干细胞移植治疗1型和2型糖尿病临床试验的回顾性分析研究进展
Jang Cho,Matthew D&#x;Antuono,Michael Glicksman et al.
Jang Cho et al.
Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are widely prevalent metabolic diseases with differing pathologies. T1DM manifests due to autoimmune destruction of the pancreatic beta cells, resulting in a diminished sec...
Close yet so far away: a look into the management strategies of genetic imprinting disorders [0.03%]
近在眼前却遥不可及——兼性印记紊乱的管控策略探究
Mark A Pianka,Alec T McIntosh,Sahaj D Patel et al.
Mark A Pianka et al.
Genetic imprinting is the process of epigenetic labelling or silencing of particular genes, based on the maternal or paternal origin of the gene, in a heritable pattern. The incidence of imprinting disorders has become a growing concern due...
Stem cell therapy in chronic obstructive pulmonary disease. How far is it to the clinic? [0.03%]
干细胞治疗慢性阻塞性肺疾病 离临床应用还有多远？
Nurdan Kokturk,Fatma Yıldırım,Pınar Yıldız Gülhan et al.
Nurdan Kokturk et al.
Chronic obstructive pulmonary disease (COPD) is a respiratory disease that has a major impact worldwide. The currently-available drugs mainly focus on relieving the symptoms of COPD patients. However, in the latter stages of the disease, th...
Analysis of the regulation pathways via microarray and miRNA studies: human embryonic stem cells to treat diabetes mellitus type-II [0.03%]
基因芯片和微阵列研究调控路径的分析：人类胚胎干细胞治疗二型糖尿病
Geeta Shroff,Rhea Shroff,Rakesh Gupta
Geeta Shroff
Diabetes mellitus occurs either due to an autoimmune destruction of β cells (Type 1) or resistance to insulin effects (Type 2). Diverse conventional medications are used for treatment of diabetes, which is associated with long term complic...
Comparing stemness gene expression between stem cell subpopulations from peripheral blood and adipose tissue [0.03%]
来源于外周血和脂肪组织的干细胞亚群之间的干细胞性基因表达比较分析
Maria Teresa González-Garza,Delia E Cruz-Vega,Alejandro Cárdenas-Lopez et al.
Maria Teresa González-Garza et al.
Cell therapy presents a promising alternative for the treatment of degenerative diseases. The main sources of adult stem cells are bone marrow, adipose tissue and peripheral blood. Within those tissues, there are cell subpopulations that sh...