Safety and feasibility of autologous adipose-derived stromal vascular fraction in the treatment of keloids: a phase one randomized controlled pilot trial [0.03%]
自体脂肪来源血管基质成分治疗瘢痕的疗效与安全性：I期随机对照试点试验
Ronald Mbiine,Anthony Kayiira,Misaki Wayengera et al.
Ronald Mbiine et al.
Introduction: Autologous adipose-derived stromal vascular fraction (SVF) has been described to have therapeutic benefits in the treatment of keloids. However, most of the evidence on its efficacy is based on observational...
Adipose-derived mesenchymal stem cell-loaded β-chitin nanofiber hydrogel activates the AldoA/HIF-1α pathway to promote diabetic wound healing [0.03%]
载有脂肪源性间充质干细胞的β-几丁糖纳米纤维水凝胶通过激活AldoA/HIF-1α通路促进糖尿病创面修复
Ying Liu,Ruihang Ma,Du Juan et al.
Ying Liu et al.
Objectives: To identify the effect of adipose-derived mesenchymal stem cell-loaded β-chitin nanofiber (ADSC-loaded β-ChNF) hydrogel on diabetic wound healing and clarify its mechanism of action. ...
The pattern of RNA integrity and the expression of housekeeping genes are influenced by sodium hypochlorite and ascorbic acid [0.03%]
次氯酸钠和抗坏血酸影响RNA完整性和管家基因表达的规律性研究
Sumreen Begum,Sehrish Jabeen,Syed Adibul Hasan Rizvi
Sumreen Begum
Background: Basic biological science research deals with nucleic acid isolation. Post-isolation nucleic acid integrity has a pivotal role in further elucidating gene expression and other molecular mechanisms. RNA (ribonuc...
TGF-B1-over-expressed adipose stem cells-derived secretome exhibits CD44 suppressor and anti-cancer properties via antagonistic effects against SMAD4 in breast cancer cells [0.03%]
过表达TGF-B1的脂肪干细胞源分泌组通过对抗乳腺癌细胞中的SMAD4表现出CD44抑制剂和抗癌特性
Hasan Salkin,Arzu Yay,Nur Seda Gokdemir et al.
Hasan Salkin et al.
Objectives: This study aimed to investigate the effect of TGF-B1-transfected adipose-derived mesenchymal stem cell (AD-MSC) conditional medium (TGF-B1-CM) on CD44 expression and biological activities in MCF-7 and MDA-MB-2...
Embryonic stem cell differentiation to primordial germ cell like cells by Nigella sativa, Brassica Oleracea and Oenothera biennis extracts [0.03%]
黑种草、芸苔和土色林鼠尾草提取物对胚胎干细胞分化为原始生殖细胞样细胞的影响
Reza Najibi,Seyed Kamal Kazemitabar,Ghaffar Kiani et al.
Reza Najibi et al.
Objectives: This study aimed to investigate the induction effects of methanolic extracts of Nigella sativa (NiS), Brassica Oleracea (BrO), and Oenothera biennia (Obi) on transgenic embryonic stem cells (ESCs) and to evalu...
Adipose-derived stromal vascular fraction (SVF) in scar treatment: a systematic review protocol [0.03%]
脂肪来源基质血管组分（SVF）在瘢痕治疗中的应用：系统评价方案
Ronald Mbiine,Misaki Wayengera,Moses Ocan et al.
Ronald Mbiine et al.
Background: Autologous adipose-derived stromal vascular fraction (SVF) is an emerging therapy that is being pioneered as a potential treatment for keloids and hypertrophic scars. Up to this point, there isn't a cure for k...
Phase 1 clinical trial for intravenous administration of mesenchymal stem cells derived from umbilical cord and placenta in patients with moderate COVID-19 virus pneumonia: results of stage 1 of the study [0.03%]
宫血干细胞和胎盘间充质干细胞静脉输注治疗中度新冠肺炎患者的I期临床研究：I期结果报告
Alok Sharma,Rohit Kulkarni,Hemangi Sane et al.
Alok Sharma et al.
Objective: Mesenchymal stem cells can serve as a therapeutic option for COVID-19. Their immunomodulatory and anti-inflammatory properties can regulate the exaggerated inflammatory response and promote recovery of lung dam...
The therapeutic effects of stem cells from human exfoliated deciduous teeth on clinical diseases: a narrative review study [0.03%]
人乳牙干细胞的临床疗效：综述研究
Fariba Naderi,Mohsen Mehdiabadi,Farideh Kamarehei
Fariba Naderi
Introduction: Stem cells isolated from human dental pulp tissue are different from other sources of Mesenchymal stem cells because of their embryonic neural crest sources and neuro-trophic potential. These stem cells cons...
Optimization of human myoblasts culture under different media conditions for application in the in vitro studies [0.03%]
不同培养条件对体外培养人肌管的影响优化研究
Natalia Rozwadowska,Maria Sikorska,Katarzyna Bozyk et al.
Natalia Rozwadowska et al.
Human primary in vitro cell cultures are among the most challenging procedures in cellular biology laboratory practice. Myoblasts-progenitor of skeletal muscle origin represent a promising therapeutic cell source since the procedure of thei...
Defects in energy metabolism are associated with functional exhaustion of bone marrow mesenchymal stem cells in cirrhosis [0.03%]
能量代谢障碍与肝硬化骨髓间充质干细胞功能衰竭有关
Dhananjay Kumar,Deepanshu Maheshwari,Nidhi Nautiyal et al.
Dhananjay Kumar et al.
Objectives: Cellular and functional exhaustion of bone marrow mesenchymal stem cells (BM-MSC) is significantly associated with the loss of HSCs and hepatic osteodystrophy in cirrhosis. The molecular mechanisms underlying ...