Bone marrow stem cell therapy in heart failure patients with low ejection fraction: a systematic review [0.03%]
低射血分数心力衰竭患者骨髓干细胞治疗的系统评价
Azin Alizadehasl,Seyedeh Fatemeh Hosseini Jebelli,Yasamin Afsari Zonooz et al.
Azin Alizadehasl et al.
The association of bone marrow stem cells (BMSCs) with cardiac function outcomes and treatment outcomes in heart failure (HF) patients with low ejection fraction (EF) has been heterogeneous across studies. This systematic review aimed to in...
Enhanced differentiation capacity of parthenogenetic embryonic stem cells via incorporation of non-growing oocyte genomes in mouse [0.03%]
通过引入非增殖卵母细胞基因组增强派生小鼠胚胎干细胞的分化能力
Hua Shao,Jie Cao,Ronghua Lu
Hua Shao
Objectives: To evaluate the in vivo developmental and therapeutic potential of a novel parthenogenetic embryonic stem cell line (NF-pES), which contains genomes from both non-growing and grown oocytes. ...
Epigenetic crosstalk between stem cells and tumors: mechanisms and emerging perspectives [0.03%]
干细胞与肿瘤间的表观遗传信号交叉：机制和前景
Wenli Zhou,Xuehai Liu,Zhaoyu Li et al.
Wenli Zhou et al.
Stem cells possess self-renewal and multipotent differentiation capabilities, exhibiting broad applications in regenerative medicine and tissue homeostasis maintenance. Their fate regulation relies heavily on precise epigenetic mechanisms. ...
The effect of decitabine on human induced pluripotent stem cells (hiPSCs) derived CD34+ cells expansion and the megakaryocytes generation and maturation [0.03%]
地西他滨对诱导多能干细胞来源CD34⁺细胞扩增及巨核细胞生成和成熟的影响研究
Yanfeng Liu,Hongyan Zhang,Yanxin Li et al.
Yanfeng Liu et al.
Background: Epigenetic modifiers play an important role in regulating the fate of hematopoietic stem cells (HSCs). The chromatin-modifying agents (CMA) have previously been shown to expand HSCs from cord blood (CB) and bo...
The predawn dilemma in adeno-associated virus-based gene therapies for hereditary deafness [0.03%]
腺相关病毒基因疗法治疗遗传性耳聋的黎明前困境
Jiao Zhou,Di Deng,Chunmei Gan et al.
Jiao Zhou et al.
Hearing loss is a prevalent organ-specific disorder affecting individuals throughout their lifespan, with over 466 million cases reported globally. The conditions can be classified into two broad categories: hereditary and nonhereditary. HH...
Platinum chemotherapeutic-induced oxidative stress affects the transcriptional response of DNA repair genes in murine mesenchymal stem cells [0.03%]
铂类化疗诱导的氧化应激影响了小鼠间充质干细胞中DNA修复基因转录反应
Sehrish Jabeen,Yasir Raza,Sumreen Begum et al.
Sehrish Jabeen et al.
Cisplatin and oxaliplatin are among the most extensively used anti-cancer drugs in the treatment of various types of cancer. However, the cytotoxicity associated with these drugs in normal and adult stem cells is a major concern. ...
Sharique A Ali,Gulafsha Kassab,Tasneem Husain
Sharique A Ali
Human melanocytes (MCs) and melanocyte stem cells (McSCs) are integral to skin pigmentation and appendage pigmentation, originating embryonically from neural crest cells. In adult skin, McSCs residing in the epidermis sustain the continuous...
Mesenchymal stem cells in injury repair of vital organs: from mechanism to clinical application [0.03%]
间充质干细胞在重要脏器损伤修复中的作用及机制研究进展及其临床应用前景
Liwei Bao,Zihan Wang,Li Li et al.
Liwei Bao et al.
Mesenchymal stem cells (MSCs) are a type of pluripotent stem cells originating from the mesoderm, known for their capability to differentiate into various specific tissue cell types and fulfill corresponding physiological roles. Furthermore...
Human umbilical cord Wharton's jelly mesenchymal cell medium progress the wound healing via cytokines and growth factors expressions [0.03%]
人脐带沃顿胶间充质细胞通过细胞因子和生长因子的表达促进伤口愈合
Tahereh Ebrahimi,Vahideh Tarhriz,Haleh Forouhandeh et al.
Tahereh Ebrahimi et al.
Objective: Conditioned medium of umbilical cord mesenchymal cells is a rich environment in various growth factors and cytokines, the use of which causes self-improvement and self-renewal in damaged tissues. ...
Investigating nanoparticle's utilization in stem cell therapy for neurological disorders [0.03%]
纳米颗粒在干细胞治疗神经系统疾病中应用的研究
Sadia Aziz,Sundus Anbreen,Shaheen Shahzad et al.
Sadia Aziz et al.
Stem cell therapy is a promising area of regenerative medicine, offering potential treatments for various life-threatening disorders. Stem cells are classified based on their differentiation potential into totipotent, pluripotent, and multi...