Activation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture [0.03%]
胎盘血细胞中的TNF家族受体的激活和串扰不会导致培养后的植入能力丧失
Keren Mizrahi,Nadir Askenasy
Keren Mizrahi
Umbilical cord blood (UCB) is a rich source of hematopoietic progenitors for transplantation. Murine and human progenitors are insensitive to apoptotic signaling mediated by the TNF family receptors, however extension of culture over 48 hou...
Therapeutic potential of Pnmt+ primer cells for neuro/myocardial regeneration [0.03%]
Pnmt+干细胞在神经和心肌再生中的治疗潜力研究
Aaron Owji,Namita Varudkar,Steven N Ebert
Aaron Owji
Phenylethanolamine n-methyltransferase (Pnmt) catalyzes the conversion of norepinephrine into epinephrine, and thus serves as a marker of adrenergic cells. In adults, adrenergic cells are present in the adrenal medullae and the central and ...
Farhard Khimani,Ryan Livengood,Olukemi Esan et al.
Farhard Khimani et al.
Copper deficiency resulting in hypocupremia is a rare cause of pancytopenia associated with a neurological syndrome. Hypocupremia may also occur as a consequence of excessive oral zinc consumption as described by Brewer et al and several ot...
Case Reports
American journal of stem cells. 2013 Jun 30;2(2):132-6. DOI: 2013
A robust method to derive functional neural crest cells from human pluripotent stem cells [0.03%]
一种从人多能干细胞中有效分离神经 crest 干细胞的方法
Faith R Kreitzer,Nathan Salomonis,Alice Sheehan et al.
Faith R Kreitzer et al.
Neural crest (NC) cells contribute to the development of many complex tissues of all three germ layers during embryogenesis, and its abnormal development accounts for several congenital birth defects. Generating NC cells-including specific ...
Amniotic fluid derived stem cells give rise to neuron-like cells without a further differentiation potential into retina-like cells [0.03%]
胎盘羊水干细胞分化形成类似神经细胞但不能进一步向视网膜细胞分化的类器官结构
K Hartmann,O Raabe,S Wenisch et al.
K Hartmann et al.
Amniotic fluid contains heterogeneous cell types and has become an interesting source for obtaining fetal stem cells. These stem cells have a high proliferative capacity and a good differentiation potential and may thus be suitable for rege...
The development of hematopoietic and mesenchymal stem cell transplantation as an effective treatment for multiple sclerosis [0.03%]
造血干细胞和间充质干细胞移植治疗多发性硬化症的临床应用进展
Jameson P Holloman,Calvin C Ho,Arushi Hukki et al.
Jameson P Holloman et al.
This article examines the current use and future implications of stem cell therapy in treating Multiple Sclerosis (MS). MS is the most common neurological disease in young adults, affecting approximately two million people worldwide. Curren...
On becoming neural: what the embryo can tell us about differentiating neural stem cells [0.03%]
神经分化：胚胎能告诉我们什么
Sally A Moody,Steven L Klein,Beverley A Karpinski et al.
Sally A Moody et al.
THE EARLIEST STEPS OF EMBRYONIC NEURAL DEVELOPMENT ARE ORCHESTRATED BY SETS OF TRANSCRIPTION FACTORS THAT CONTROL AT LEAST THREE PROCESSES: the maintenance of proliferative, pluripotent precursors that expand the neural ectoderm; their tran...
Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro [0.03%]
体外冲击波对马脂肪组织来源间充质干细胞增殖及分化影响的实验研究
O Raabe,K Shell,A Goessl et al.
O Raabe et al.
Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are responsible for tissue regeneration in the course of musculoskeletal disorders. In equine veterinary medicine extracorporeal shock wave ...
Cancer stem cells and tumor transdifferentiation: implications for novel therapeutic strategies [0.03%]
癌症干细胞和肿瘤转分化：对新型治疗策略的意义
Mohammed Talha Shekhani,Ashika-Sita Jayanthy,Nityanand Maddodi et al.
Mohammed Talha Shekhani et al.
Highly malignant tumors mostly consist of rapidly proliferating cells. However, tumors also contain a few cells in a quiescent state that can be characterized as slow-cycling, expressing markers of stem cells and possessing the ability to i...
Genetic instability of modified stem cells - a first step towards malignant transformation? [0.03%]
基因修饰干细胞的遗传不稳定是恶性转化的第一步吗？
Doris Steinemann,Gudrun Göhring,Brigitte Schlegelberger
Doris Steinemann
Induced pluripotent stem cells (iPSC) are important tools in regenerative medicine. Yet, it is becoming increasingly clear that the reprogramming process, including retroviral transduction with potent oncogenes like c-Myc and long-term cult...