Transdifferentiation of endothelial cells to smooth muscle cells play an important role in vascular remodelling [0.03%]
内皮细胞向平滑肌细胞的转分化在血管重构中起着重要作用
Núria Coll-Bonfill,Melina Mara Musri,Victor Ivo et al.
Núria Coll-Bonfill et al.
Pulmonary artery remodelling it is a major feature of pulmonary hypertension (PH). It is characterised by cellular and structural changes of the pulmonary arteries causing higher pulmonar vascular resistance and right ventricular failure. A...
Adipose tissue derived mesenchymal stem cells for musculoskeletal repair in veterinary medicine [0.03%]
脂肪来源的间充质干细胞在兽医临床肌肉骨骼修复中的应用
Stefan Arnhold,Sabine Wenisch
Stefan Arnhold
Adipose tissue derived stem cells (ASCs) are mesenchymal stem cells which can be obtained from different adipose tissue sources within the body. It is an abundant cell pool, which is easy accessible and the cells can be obtained in large nu...
Hematopoietic stem cells derived from human umbilical cord ameliorate cisplatin-induced acute renal failure in rats [0.03%]
人源脐带造血干细胞移植改善大鼠顺铂急性肾功能衰竭的研究
Rokaya H Shalaby,Laila A Rashed,Alaa E Ismaail et al.
Rokaya H Shalaby et al.
Injury to a target organ can be sensed by bone marrow stem cells that migrate to the site of damage, undergo differentiation, and promote structural and functional repair. This remarkable stem cell capacity prompted an investigation of the ...
Dana Zeineddine,Aya Abou Hammoud,Mohamad Mortada et al.
Dana Zeineddine et al.
The Oct4 protein, encoded by the Pou5f1 gene was the very first master gene, discovered 25 years ago, to be absolutely required for the stemness properties of murine and primate embryonic stem cells. This transcription factor, which has als...
Hui-Juan Jiang,Shuang Wang,Yanqing Ding
Hui-Juan Jiang
A large number of long non-coding RNAs (lncRNAs) have been discovered by genome-wide transcriptional analyses. Emerging evidence has indicated that lncRNAs regulate gene expression at epigenetic, transcription, and post-transcription levels...
Wen-Ting Liao,Ya-Ping Ye,Yong-Jian Deng et al.
Wen-Ting Liao et al.
Metastatic cancer stem cells (MCSCs) refer to a subpopulation of cancer cells with both stem cell properties and invasion capabilities that contribute to cancer metastasis. MCSCs have capability of self-renewal, potentials of multiple diffe...
Phenotype-dependent role of the L-type calcium current in embryonic stem cell derived cardiomyocytes [0.03%]
胚胎干细胞源性心肌细胞中L型钙电流的表型依赖性作用
Pauline Dan,Zheng Zeng,Ying Li et al.
Pauline Dan et al.
Although the L-type Ca(2+) current (ICa,L) plays an important role in cardiac contractility and pacemaking, its role in embryonic stem-cell derived cardiomyocytes (ESC-CMs) has not yet been explored in detail. We used patch-clamp techniques...
Rapid isolation of integrin rich multipotent stem cell pool and reconstruction of mouse epidermis equivalent [0.03%]
快速分离富整合素多能干细胞群并重建相当于小鼠表皮的组织
Sushil Kumar,Shiv Poojan,Vikas Verma et al.
Sushil Kumar et al.
We describe here epidermis reconstruction using multipotent mouse epidermal stem cells (EpSCs) enriched from keratinocyte isolates exploting exclusively the stem cell-adhesive property. This method excluded flowcytometry and was swift. Perc...
Effect of transplantation of human embryonic stem cell-derived neural progenitor cells on adult neurogenesis in aged hippocampus [0.03%]
人胚胎干细胞源性神经前体细胞移植对老龄海马区成人神经元生成的影响
Sufang Liu,Changsheng Li,Ying Xing et al.
Sufang Liu et al.
Adult neurogenesis occurs within the special microenvironment in the subgranular zone of the hippocampus and the subventricular zone of the lateral ventricle of the mammalian brain. The special microenvironment is known as neurogenic niches...
Francesco Moroni,Teodelinda Mirabella
Francesco Moroni
Cardiovascular disease (CVD) is one of the leading causes of death in the Western world. The replacement of damaged vessels and valves has been practiced since the 1950's. Synthetic grafts, usually made of bio-inert materials, are long-last...