A novel gain-of-function mutation SCN5A-N470K associated with African American familial atrial fibrillation [0.03%]
与非裔美国人房颤家系相关的新型SCN5A-N470K功能获得性突变
Xinyu Cao,Faisal A Darbar,Xin Wu et al.
Xinyu Cao et al.
Objectives: The cardiac sodium channel Nav1.5, encoded by the SCN5A gene, is crucial for the generation and propagation of cardiac action potential. While SCN5A mutations have been linked to familial atrial fibrillation (...
Pyroptosis in cardiovascular diseases: molecular mechanisms, pathological roles, and therapeutic implications [0.03%]
心血管疾病中的细胞炎性焦亡:分子机制、病理作用和治疗意义
Xue-Song Liu,Zhao-Yu Li,Shi-Tong Wang et al.
Xue-Song Liu et al.
Each year, cardiovascular diseases (CVDs) claim millions of lives worldwide, making them one of the biggest causes of deaths globally. More often than not, the inflammatory response is the principal disease mechanism behind the onset and de...
Deep learning models for predicting heart disease risk using the UCI database: methods, performance, and clinical context [0.03%]
利用UCI数据库预测心脏病风险的深度学习模型:方法、性能和临床背景
Reza Khademi,Golnaz Yazdanpanah,Ghazaleh Rouhparvarzamin et al.
Reza Khademi et al.
Objectives: To develop and evaluate deep learning models for predicting heart disease using the University of California, Irvine (UCI) heart disease dataset, and to contextualize model performance against classical machin...
Impact of prior pacemaker implantation on length of stay in acute diastolic heart failure: a propensity score-matched analysis [0.03%]
起搏器植入对急性舒张性心力衰竭住院时间的影响:倾向分值匹配分析
Ashot Batikyan,Vahagn Tamazyan,Hakob Harutyunyan et al.
Ashot Batikyan et al.
Objectives: Permanent pacemakers are widely used to manage symptomatic bradyarrhythmias and conduction disorders; however, their impact on hospitalization outcomes, such as length of stay, in patients with acute decompens...
Pre-transplant hemodynamic profiles of patients with ischemic vs. non-ischemic cardiomyopathy: insights from a retrospective single-center study [0.03%]
缺血性和非缺血性心肌病患者移植前的心动力学特征:来自回顾性单中心研究的启示
Mohammad Reza Movahed,Shiva Aminnia
Mohammad Reza Movahed
Objectives: Heart transplantation remains the last resort for patients with end-stage heart failure. The clinical and hemodynamic profiles of these patients may differ depending on the underlying etiology of cardiomyopath...
Effect of external magnetic and electric fields on blood flow and drug transport in a cardiovascular tube [0.03%]
外部磁场和电场对心血管管中血液流动及药物输运的影响
Binyam Zigta Teferi
Binyam Zigta Teferi
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, and efficient drug delivery (DD) is critical for treatment success. The use of external electric (EF) and magnetic fields (MF) offers a promising approach to enhanc...
Efficacy of exercise and electromagnetic field therapy on cardiovascular disease risk in patients with type 2 diabetes mellitus. Randomized controlled trial [0.03%]
运动和电磁场疗法对2型糖尿病患者心血管疾病风险影响的随机对照试验
Ashraf Abdelaal Mohamed Abdelaal,Alaa Abdulhafiz Khushhal,Anwar Abdelgayed Ebid et al.
Ashraf Abdelaal Mohamed Abdelaal et al.
Type 2 diabetes mellitus predisposes patients to abnormally increased atherosclerotic cardiovascular disease risk and deteriorated lower extremity functional status. Objective: To evaluate the effect of combined application of moderate to h...
Effectiveness of nurse-led video monitoring for maintaining self-care in heart failure patients: study protocol for a randomized clinical trial [0.03%]
基于视频的监测维持心力衰竭患者自我护理的护士领导模式有效性的随机对照试验方案研究
Omar Pereira De Almeida Neto,Izadora Vieira Araújo,Maria Eduarda de Pádua Alcântara et al.
Omar Pereira De Almeida Neto et al.
It is well established that video monitoring is effective in promoting self-care among patients with heart failure during the intervention period. However, its long-term impact on sustaining self-care behaviors after discontinuation remains...
Advances in cardiovascular gene therapy: a systematic review of nanoparticle-based delivery strategies for atherosclerosis [0.03%]
心血管基因治疗的进展:动脉粥样硬化纳米药物递送策略的系统性复习
Mahan Khani,Kianoush Shahryari,Samira Masoumi et al.
Mahan Khani et al.
Background: Atherosclerosis (AS), the primary cause of cardiovascular morbidity and mortality, involves chronic vascular inflammation and plaque formation. While conventional therapies target systemic risk factors, their ...
Impact of lead placement site on right ventricular function: a comparative echocardiographic analysis of apical versus septal pacing in permanent pacemaker recipients [0.03%]
起搏部位不同对右心室功能的影响:永久起搏器植入术后心尖部与间隔部起搏的超声心动图对比分析
Reza Ariannia,Amirhossein Badkoubi,Dorsa Shirini et al.
Reza Ariannia et al.
Objectives: Permanent pacemaker (PPM) implantation is a standard intervention for bradyarrhythmias, yet the long-term hemodynamic consequences of right ventricular (RV) lead positioning remain underexplored. While apical ...