Ferroptosis in ischemia-reperfusion injury: molecular mechanisms and therapeutic strategies [0.03%]
缺血再灌注损伤中的铁死亡：分子机制和治疗策略
Ya-Li Wei,Lu Cheng,Xiao-Yu Chen et al.
Ya-Li Wei et al.
Ferroptosis is a novel form of programmed cell death characterized by iron-dependent lipid peroxidation (LPO). It has been widely demonstrated in the last years to play a crucial pathogenic role in ischemia-reperfusion injury (IRI). The pat...
miRNA regulatory networks as precision diagnostic and therapeutic targets in pulmonary arterial hypertension: from molecular cascades to clinical translation [0.03%]
microRNA调控网络作为精准诊断和治疗肺动脉高压的靶点：从分子通路到临床转化
Zhaoyu Li,Hongyang Ding,Xuehai Liu et al.
Zhaoyu Li et al.
Pulmonary arterial hypertension (PAH) is a fatal disease with extremely poor prognosis, primarily driven by persistent pulmonary vascular remodeling. The disease often presents insidiously and progresses rapidly. Although current targeted t...
Ubiquitination-mediated protein homeostasis in cardiovascular diseases: molecular mechanisms and therapeutic opportunities [0.03%]
泛素介导的心血管疾病蛋白质稳态：分子机制与治疗策略
Yanfei Wang,Xuesong Liu,Yong Hu et al.
Yanfei Wang et al.
Cardiovascular diseases (CVDs) remain one of the leading causes of death worldwide. Although the well-known risk factors include hypertension, hyperglycemia, dyslipidemia and obesity, the latest studies implicate involvement of pathological...
A normal and particularly small left atrial size measured during echocardiography MAY NOT suggest low likelihood of moderate or severe left ventricular systolic dysfunction [0.03%]
经超声心动图测量的正常的和特别小的左心房大小不能表明中至重度左心室收缩功能障碍低可能性
Gregory Mints,Jina Bai,Arthur Evans
Gregory Mints
This is letter to the editor: we point to a statistical error in a recent article published in the journal by Movahed MR, Soltani Moghadam A. A normal and particularly small (
A novel gain-of-function mutation SCN5A-N470K associated with African American familial atrial fibrillation [0.03%]
与非裔美国人房颤家系相关的新型SCN5A-N470K功能获得性突变
Xinyu Cao,Faisal A Darbar,Xin Wu et al.
Xinyu Cao et al.
Objectives: The cardiac sodium channel Nav1.5, encoded by the SCN5A gene, is crucial for the generation and propagation of cardiac action potential. While SCN5A mutations have been linked to familial atrial fibrillation (...
Pyroptosis in cardiovascular diseases: molecular mechanisms, pathological roles, and therapeutic implications [0.03%]
心血管疾病中的细胞炎性焦亡：分子机制、病理作用和治疗意义
Xue-Song Liu,Zhao-Yu Li,Shi-Tong Wang et al.
Xue-Song Liu et al.
Each year, cardiovascular diseases (CVDs) claim millions of lives worldwide, making them one of the biggest causes of deaths globally. More often than not, the inflammatory response is the principal disease mechanism behind the onset and de...
Deep learning models for predicting heart disease risk using the UCI database: methods, performance, and clinical context [0.03%]
利用UCI数据库预测心脏病风险的深度学习模型：方法、性能和临床背景
Reza Khademi,Golnaz Yazdanpanah,Ghazaleh Rouhparvarzamin et al.
Reza Khademi et al.
Objectives: To develop and evaluate deep learning models for predicting heart disease using the University of California, Irvine (UCI) heart disease dataset, and to contextualize model performance against classical machin...
Impact of prior pacemaker implantation on length of stay in acute diastolic heart failure: a propensity score-matched analysis [0.03%]
起搏器植入对急性舒张性心力衰竭住院时间的影响：倾向分值匹配分析
Ashot Batikyan,Vahagn Tamazyan,Hakob Harutyunyan et al.
Ashot Batikyan et al.
Objectives: Permanent pacemakers are widely used to manage symptomatic bradyarrhythmias and conduction disorders; however, their impact on hospitalization outcomes, such as length of stay, in patients with acute decompens...
Pre-transplant hemodynamic profiles of patients with ischemic vs. non-ischemic cardiomyopathy: insights from a retrospective single-center study [0.03%]
缺血性和非缺血性心肌病患者移植前的心动力学特征：来自回顾性单中心研究的启示
Mohammad Reza Movahed,Shiva Aminnia
Mohammad Reza Movahed
Objectives: Heart transplantation remains the last resort for patients with end-stage heart failure. The clinical and hemodynamic profiles of these patients may differ depending on the underlying etiology of cardiomyopath...
Effect of external magnetic and electric fields on blood flow and drug transport in a cardiovascular tube [0.03%]
外部磁场和电场对心血管管中血液流动及药物输运的影响
Binyam Zigta Teferi
Binyam Zigta Teferi
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, and efficient drug delivery (DD) is critical for treatment success. The use of external electric (EF) and magnetic fields (MF) offers a promising approach to enhanc...