A sol-gel-integrated protein array system for affinity analysis of aptamer-target protein interaction [0.03%]
一种用于表征适配子-蛋白质相互作用亲和力的溶胶-凝胶集成蛋白芯片系统
Ji-Young Ahn,Eunkyung Kim,Jeehye Kang et al.
Ji-Young Ahn et al.
A sol-gel microarray system was developed for a protein interaction assay with high activity. Comparing to 2-dimensional microarray surfaces, sol-gel can offer a more dynamic and broad range for proteins. In the present study, this sol-gel-...
In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells [0.03%]
体外筛选RNA适配子并特异性靶向乳腺癌细胞中的ErbB2蛋白质
Mee Young Kim,Sunjoo Jeong
Mee Young Kim
The ErbB family (also referred to as HER/neu or HER) of receptor tyrosine kinases plays major roles in the formation and progression of human tumors. Amplification and/or overexpression of ErbB2 have been reported in numerous cancers, inclu...
In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells [0.03%]
体外筛选RNA适配子并特异靶向乳腺癌细胞的ErbB2蛋白
Mee Young Kim,Sunjoo Jeong
Mee Young Kim
The ErbB family (also referred to as HER/neu or HER) of receptor tyrosine kinases plays major roles in the formation and progression of human tumors. Amplification and/or overexpression of ErbB2 have been reported in numerous cancers, inclu...
Enhanced transfection rates of small-interfering RNA using dioleylglutamide-based magnetic lipoplexes [0.03%]
基于磁性脂质体的二油酰氨基葡萄糖衍生物的小干扰RNA转染率增强研究
Soondong Lee,Gayong Shim,Sunil Kim et al.
Soondong Lee et al.
Magnetic force-guided delivery (magnetofection) has been studied as a new modality for introducing small-interfering RNA (siRNA) into target cells, but its delivery efficiency needs to be improved. Here, we report that magnetofection of N,N...
An RNA aptamer that selectively recognizes symmetric dimethylation of arginine 8 in the histone H3 N-terminal peptide [0.03%]
一种识别组蛋白H3 N端肽中精氨酸8对称二甲基化的RNA适配体
Soonsil Hyun,Kyung Hyun Lee,Areum Han et al.
Soonsil Hyun et al.
Epigenetic modifications of N-terminal histone tails, especially histone H3, are important for the regulation of the target genes in chromatin. Specific methods for detection of these modifications in histone H3 N-terminal peptides are valu...
Long double-stranded RNA-mediated RNA interference and immunostimulation: long interfering double-stranded RNA as a potent anticancer therapeutics [0.03%]
长双链RNA介导的RNA干扰和免疫刺激：具有抗癌疗效的长干扰双链RNA
Chan Il Chang,Tae Yeon Lee,Pooja Dua et al.
Chan Il Chang et al.
In most applications, small interfering RNAs are designed to execute specific gene silencing via RNA interference (RNAi) without triggering nonspecific responses such as immunostimulation. However, in anticancer therapeutics, immunostimulat...
Kaushik Singha,Ran Namgung,Won Jong Kim
Kaushik Singha
This review will cover the current strategies that are being adopted to efficiently deliver small interfering RNA using nonviral vectors, including the use of polymers such as polyethylenimine, poly(lactic-co-glycolic acid), polypeptides, c...
Kaushik Singha,Ran Namgung,Won Jong Kim
Kaushik Singha
This review will cover the current strategies that are being adopted to efficiently deliver small interfering RNA using nonviral vectors, including the use of polymers such as polyethylenimine, poly(lactic-co-glycolic acid), polypeptides, c...
Structural diversity repertoire of gene silencing small interfering RNAs [0.03%]
基因沉默的小干扰RNA的结构多样性组合库
Chan Il Chang,Helena Andrade Kim,Pooja Dua et al.
Chan Il Chang et al.
Since the discovery of double-stranded (ds) RNA-mediated RNA interference (RNAi) phenomenon in Caenorhabditis elegans, specific gene silencing based upon RNAi mechanism has become a novel biomedical tool that has extended our understanding ...
Structural diversity repertoire of gene silencing small interfering RNAs [0.03%]
基因沉默的小干扰RNA结构多样性组合库
Chan Il Chang,Helena Andrade Kim,Pooja Dua et al.
Chan Il Chang et al.
Since the discovery of double-stranded (ds) RNA-mediated RNA interference (RNAi) phenomenon in Caenorhabditis elegans, specific gene silencing based upon RNAi mechanism has become a novel biomedical tool that has extended our understanding ...