Autoinhibitory mechanisms of ERG studied by molecular dynamics simulations [0.03%]
分子动力学模拟研究ERG的自抑制机制
Yan Lu,Freddie R Salsbury Jr
Yan Lu
ERG, an ETS-family transcription factor, acts as a regulator of differentiation of early hematopoietic cells. It contains an autoinhibitory domain, which negatively regulates DNA-binding. The mechanism of autoinhibitory is still illusive. T...
Generalizing thermodynamic properties of bulk single-walled carbon nanotubes [0.03%]
关于大尺寸单壁碳纳米管热力学性质的通用模型研究进展
Kenneth R Rodriguez,Marvin A Malone,Warren A Nanney et al.
Kenneth R Rodriguez et al.
The enthalpy and Gibbs free energy thermodynamical potentials of single walled carbon nanotubes were studied of all types (armchairs, zig-zags, chirals (n>m), and chiral (n
Benjamin Migliori,Massimiliano Di Ventra,William Kristan Jr
Benjamin Migliori
We present a method for achieving temporally and spatially precise photoactivation of neurons without the need for genetic expression of photosensitive proteins. Our method depends upon conduction of thermal energy via absorption by chemica...
Low dose hard x-ray contact microscopy assisted by a photoelectric conversion layer [0.03%]
由光电转换层辅助的低剂量硬X射线接触显微术
Andrew Gomella,Eric W Martin,Susanna K Lynch et al.
Andrew Gomella et al.
Hard x-ray contact microscopy provides images of dense samples at resolutions of tens of nanometers. However, the required beam intensity can only be delivered by synchrotron sources. We report on the use of a gold photoelectric conversion ...
Possible room temperature superconductivity in conductors obtained by bringing alkanes into contact with a graphite surface [0.03%]
室温导体超导性的可能性：碳烷和石墨接触形成的化合物中的潜在室温超导性
Yasushi Kawashima
Yasushi Kawashima
Electrical resistances of conductors obtained by bringing alkanes into contact with a graphite surface have been investigated at room temperatures. Ring current in a ring-shaped container into which n-octane-soaked thin graphite flakes were...
Kevin Loutherback,Joseph D&#x;Silva,Liyu Liu et al.
Kevin Loutherback et al.
Circulating tumor cells (CTCs) and circulating clusters of cancer and stromal cells have been identified in the blood of patients with malignant cancer and can be used as a diagnostic for disease severity, assess the efficacy of different t...
Dynamic density functional theory of solid tumor growth: Preliminary models [0.03%]
固体肿瘤生长的动态密度函数理论模型：初步模型
Arnaud Chauviere,Haralambos Hatzikirou,Ioannis G Kevrekidis et al.
Arnaud Chauviere et al.
Cancer is a disease that can be seen as a complex system whose dynamics and growth result from nonlinear processes coupled across wide ranges of spatio-temporal scales. The current mathematical modeling literature addresses issues at variou...
Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors [0.03%]
集成活体显微镜和数学建模以优化纳米药物向肿瘤的递送
Anne L van de Ven,Min Wu,John Lowengrub et al.
Anne L van de Ven et al.
Inefficient vascularization hinders the optimal transport of cell nutrients, oxygen, and drugs to cancer cells in solid tumors. Gradients of these substances maintain a heterogeneous cell-scale microenvironment through which drugs and their...
Chris Cleveland,David Liao,Robert Austin
Chris Cleveland
This is a theoretical paper which examines at a game theoretical perspective the dynamics of cooperators and cheater cells under metabolic stress conditions and high spatial heterogeneity. Although the ultimate aim of this work is to unders...
Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression [0.03%]
量子代谢和自然选择对癌细胞起源和肿瘤发展的启示
Paul Davies,Lloyd A Demetrius,Jack A Tuszynski
Paul Davies
Empirical studies give increased support for the hypothesis that the sporadic form of cancer is an age-related metabolic disease characterized by: (a) metabolic dysregulation with random abnormalities in mitochondrial DNA, and (b) metabolic...