Hajo Meyer,Michael Meischein,Alfred Ludwig
Hajo Meyer
A high-throughput method is presented for the efficient assessment of the formation and stability of nanoparticle suspensions in ionic liquids which differ in their cations and anions. As a proof of principle, Ag was sputtered on a cavity a...
Influences of W Content on the Phase Transformation Properties and the Associated Stress Change in Thin Film Substrate Combinations Studied by Fabrication and Characterization of Thin Film V1- xW xO2 Materials Libraries [0.03%]
W含量对薄膜衬底组合物相变性质及应力变化的影响研究——基于V1-xWxO2薄膜材料库的构筑与表征
Xiao Wang,Detlef Rogalla,Alfred Ludwig
Xiao Wang
The mechanical stress change of VO2 film substrate combinations during their reversible phase transformation makes them promising for applications in micro/nanoactuators. V1- xW xO2 thin film libraries were fabricated by reactive combinator...
A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts [0.03%]
一种化学改良提取物的活性化合物：靶向克鲁兹锥虫溴结构域抑制剂
I Ayelen Ramallo,Victoria L Alonso,Federico Rua et al.
I Ayelen Ramallo et al.
A set of chemically engineered extracts enriched in compounds including N-N and N-O fragments in their structures was prepared. Bromodomain binding screening and bioguided fractionation led to the identification of one oxime hit that intera...
Min-Kyung Shin,Yu-Jung Hyun,Ji Hoon Lee et al.
Min-Kyung Shin et al.
Cyclic peptoids are emerging as an attractive class of peptidomimetics. Compared to their linear counterparts, cyclic peptoids should have increased conformational rigidity and preorganized structures, enabling them to bind more tightly to ...
Comparative Study
ACS combinatorial science. 2018 Apr 9;20(4):237-242. DOI:10.1021/acscombsci.7b00194 2018
Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR [0.03%]
通过Ugi四组分反应和Passerini三组分反应合成高度取代的咪唑嘧啶化合物
Rudrakshula Madhavachary,Tryfon Zarganes-Tzitzikas,Pravin Patil et al.
Rudrakshula Madhavachary et al.
The synthesis of uracil/thymine containing tetra/trisubstituted imidazole derivatives was demonstrated using Ugi/Passerini-reaction followed by a postcyclization reaction sequence. The approach enables the one-pot facile construction of div...
Catherine Fagundez,Diver Sellanes,Gloria Serra
Catherine Fagundez
The results from the synthesis of peptides by Fmoc/SPPS on a 2-CTC resin and then lactamization in solution or solid phase for the preparation of cyclopeptides are presented. Both procedures allow the synthesis of the desired compounds in g...
Solid-Phase Synthesis of Pyrrole Derivatives through a Multicomponent Reaction Involving Lys-Containing Peptides [0.03%]
含赖氨酸肽参与的多组分反应固相合成吡咯衍生物
Yahya E Jad,Santosh K Gudimella,Thavendran Govender et al.
Yahya E Jad et al.
The synthesis of pyrroles has received considerable attention because of their biological and pharmaceutical activities. Herein we describe a solid-phase multicomponent reaction that utilizes Lys as a N donor, β-nitrostyrenes, 1,3-dicarbon...
Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B Analogs [0.03%]
环己肽wollamides B类似物的固相合成及抗菌活性研究
Lissa S Tsutsumi,John M Elmore,Uyen T Dang et al.
Lissa S Tsutsumi et al.
Herein we report the antibacterial structure-activity relationships of cyclic hexapeptide wollamide analogs derived from solid-phase library synthesis. Wollamide B, a cyclic hexapeptide natural product, has been previously found to have act...
Regioselective Synthesis of Pyranone-Fused Indazoles via Reductive Cyclization and Alkyne Insertion [0.03%]
经由还原环化和炔烃插入合成区域选择性稠合吡喃酮吲达唑类化合物
Tz-Yi Wu,Sandip Dhole,Manikandan Selvaraju et al.
Tz-Yi Wu et al.
A novel and efficient method for the one-pot synthesis of 2 H-indazole from readily available building blocks is reported. The reaction of 2-nitrobenzylamines with zinc and ammonium formate underwent partial reduction to nitroso-benzylamine...
Rapid Construction of Fe-Co-Ni Composition-Phase Map by Combinatorial Materials Chip Approach [0.03%]
基于组合材料芯片方法的Fe-Co-Ni系成分-相图快速绘制研究
Hui Xing,Bingbing Zhao,Yujie Wang et al.
Hui Xing et al.
One hundred nanometer thick Fe-Co-Ni material chips were prepared and isothermally annealed at 500, 600, and 700 °C, respectively. Pixel-by-pixel composition and structural mapping was performed by microbeam X-ray at synchrotron light sour...