Ni-Nitrilotriacetic Acid Affinity SELEX Method for Selection of DNA Aptamers Specific to the N-Cadherin Protein [0.03%]
用于选择N-钙黏着蛋白特异性DNA适配体的Ni-NTA亲和SELEX方法
Luyan Yang,Tian Gao,Wenjing Li et al.
Luyan Yang et al.
Nucleic acid aptamers are single-stranded oligonucleotides that may be evolved for affinity and specificity for their targets and can be easily produced, regenerated, and stabilized. In this study, we adapted Ni-NTA (nickle-charged nitrilot...
Profiling SARS-CoV-2 Main Protease (MPRO) Binding to Repurposed Drugs Using Molecular Dynamics Simulations in Classical and Neural Network-Trained Force Fields [0.03%]
基于分子动力学模拟的SARS-CoV-2主要蛋白酶(MPRO)与再利用药物结合研究：经典力场和神经网络训练力场
Aayush Gupta,Huan-Xiang Zhou
Aayush Gupta
The current COVID-19 pandemic caused by a novel coronavirus SARS-CoV-2 urgently calls for a working therapeutic. Here, we report a computation-based workflow for efficiently selecting a subset of FDA-approved drugs that can potentially bind...
Bi Alloying into Rare Earth Double Perovskites Enhances Synthesizability and Visible Light Absorption [0.03%]
稀土双钙钛矿中添加Bi改善合成性和可见光吸收性能
Paul F Newhouse,Lan Zhou,Mitsutaro Umehara et al.
Paul F Newhouse et al.
A high throughput combinatorial synthesis utilizing inkjet printing of precursor inks was used to rapidly evaluate Bi-alloying into double perovskite oxides for enhanced visible light absorption. The fast visual screening of photo image sca...
Duncan R Sutherland,Aine Boyer Connolly,Maximilian Amsler et al.
Duncan R Sutherland et al.
Recent advances in high-throughput experimentation for combinatorial studies have accelerated the discovery and analysis of materials across a wide range of compositions and synthesis conditions. However, many of the more powerful character...
High-Throughput Exploration of Metal Vanadate Thin-Film Systems (M-V-O, M = Cu, Ag, W, Cr, Co, Fe) for Solar Water Splitting: Composition, Structure, Stability, and Photoelectrochemical Properties [0.03%]
高通量探索金属钒酸盐薄膜体系(M-V-O，M= Cu、Ag、W、Cr、Co、Fe)的光电化学性能及稳定性、结构、成分关系：用于太阳能分解水体系
Swati Kumari,João R C Junqueira,Wolfgang Schuhmann et al.
Swati Kumari et al.
Combinatorial synthesis and high-throughput characterization of thin-film materials libraries enable to efficiently identify both photoelectrochemically active and inactive, as well as stable and instable systems for solar water splitting. ...
Progress in Natural Compounds/siRNA Co-delivery Employing Nanovehicles for Cancer Therapy [0.03%]
用于癌症治疗的纳米载体传输天然化合物/siRNA联合输送研究进展
Milad Ashrafizadeh,Ali Zarrabi,Kiavash Hushmandi et al.
Milad Ashrafizadeh et al.
Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel, docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy because of the outstanding therapeutic activity and multitargeting capa...
Development of Measurement Tools for High-Throughput Experiments of Synchrotron Radiation XRD and XAFS on Powder Libraries [0.03%]
同步辐射XRD和XAFS高通量粉末库实验测量技术的发展
Kenjiro Fujimoto,Akihisa Aimi,Shingo Maruyama
Kenjiro Fujimoto
We propose to minimize the sampling time for high-throughput measurements of powder X-ray diffraction (XRD) and X-ray absorption fine structure (XAFS) in synchrotron radiation. The conventional synchrotron radiation powder X-ray diffraction...
Simultaneous Measurements of Photoabsorption and Photoelectrochemical Performance for Thickness Optimization of a Semiconductor Photoelectrode [0.03%]
半导体光电极光吸收和光电化学性能的同时测量用于厚度优化
Naoya Murakami,Ryo Watanabe
Naoya Murakami
We established a system for simultaneous measurements of photoelectrochemical (PEC) reaction and photoabsorption in a semiconductor photoelectrode. This system uses a photoacoustic technique and photoelectrodes with a film-thickness gradien...
Use of Target-Displaying Magnetized Yeast in Screening mRNA-Display Peptide Libraries to Identify Ligands [0.03%]
利用展示靶标的磁性酵母筛选mRNA展示多肽库以鉴别配体的应用
Kaitlyn Bacon,John Bowen,Hannah Reese et al.
Kaitlyn Bacon et al.
This work presents the first use of yeast-displayed protein targets for screening mRNA-display libraries of cyclic and linear peptides. The WW domains of Yes-Associated Protein 1 (WW-YAP) and mitochondrial import receptor subunit TOM22 were...
Optimization of Criteria for an Efficient Screening of New Thermoelectric Compounds: The TiNiSi Structure-Type as a Case-Study [0.03%]
高效筛选新型热电化合物准则的优化：以TiNiSi结构类型为例研究
Celine Barreteau,Jean-Claude Crivello,Jean-Marc Joubert et al.
Celine Barreteau et al.
High-throughput calculations can be applied to a large number of compounds, in order to discover new useful materials. In the present work, ternary intermetallic compounds are investigated, to find new potentially interesting materials for ...