Association between perioperative opioid consumption and postoperative outcomes in lung cancer surgery: evidence from a retrospective study with inflammatory and immune biomarker analysis [0.03%]
肺癌手术患者围术期阿片类药物消耗与术后结局的关联性分析:一项回顾性研究及其炎性和免疫生物标志物分析
Ruogen Li,Wuhua Ma
Ruogen Li
Opioids are crucial for lung cancer postoperative analgesia, but perioperative dosage-inflammation/immunity associations remain unclear. This study explores perioperative opioid use and inflammation/immunity biomarker changes in lung cancer...
Efficacy of chemotherapy combined with immune checkpoint inhibitors for advanced non-small cell lung cancer and construction and validation of a prognostic model: a multicenter retrospective cohort study [0.03%]
化疗联合免疫检查点抑制剂治疗晚期非小细胞肺癌的疗效及预后模型的构建与验证:一项多中心回顾性队列研究
Chunmei Gong,Fenghong Lv,Beibei Xiong et al.
Chunmei Gong et al.
The goal of this multicenter retrospective cohort study was to determine the efficacy of chemotherapy in combination with immune checkpoint inhibitors (ICIs) as compared to chemotherapy alone in patients with advanced non-small cell lung ca...
Ferroptosis and Ferroptosis-related autophagy: new therapeutic targets for gastric cancer [0.03%]
铁死亡及铁死亡相关自噬:胃癌治疗新靶点
Lingling Huang,Tingting Tan,Yingyu Mao et al.
Lingling Huang et al.
Gastric cancer (GC) is still the biggest factor in cancer-related death worldwide, and existing therapies have low therapeutic effectiveness. A possible cancer treatment target is ferroptosis, an iron-dependent kind of lipid peroxidation-in...
Pediatric sequential organ failure assessment score predicts prognosis in children with acute lymphoblastic leukemia and sepsis: association with early multiple organ dysfunction [0.03%]
儿科序贯性脏器功能衰竭评分可预测急性淋巴细胞白血病合并感染患儿预后:与早期多器官功能障碍的关系
Zhongwei Yin,Chengqi Shen,Yulin Chen et al.
Zhongwei Yin et al.
Objective: To systematically analyze the clinical characteristics and prognostic factors of children with acute lymphoblastic leukemia (ALL) complicated by sepsis, and to compare the predictive efficacy of different scori...
SP1-IKBIP axis promotes the proliferation and invasion of glioma with Wnt/β-catenin associated epithelial-mesenchymal transition [0.03%]
SP1-IKBIP轴通过Wnt/β-连环蛋白相关上皮间质转化促进胶质瘤的增殖和侵袭
Nan Liu,Mingyue Zhao,Lei Xu et al.
Nan Liu et al.
Glioma is the most aggressive tumor of the central nervous system and is associated with poor prognosis, especially in patients with high-grade gliomas. In this study, we investigated the biological role of inhibitor of kappa B kinase inter...
Rare NUP98::SETBP1 fusion transcript in a refractory adult T-cell lymphoblastic lymphoma [0.03%]
成人T细胞淋巴母细胞淋巴瘤中罕见的NUP98-SETBP1融合转录本
Xiaoyong Chen,Linlin Wang,Junyan Zou et al.
Xiaoyong Chen et al.
T-lymphoblastic lymphoma (T-LBL) is an aggressive malignancy of T-lymphoid precursors, rarely co-occurring with consequent rearrangement of nucleoporin 98 (NUP98) gene. The NUP98::SETBP1 fusion gene was first reported in a de novo T-cell ac...
Analysis of influencing factors of recurrence after thoracoscopic resection in patients with Stage I a lung adenocarcinoma [0.03%]
电视胸腔镜手术治疗IA期肺腺癌术后复发的危险因素分析
Rui-Shi Wei,Jie Ma,Xin-Hua Li et al.
Rui-Shi Wei et al.
This study aimed to investigate the influencing factors of recurrence after thoracoscopic resection in patients with Stage I a lung adenocarcinoma. The derivation cohort consisted of 104 patients admitted between February 2020 and December ...
Nomogram outperforms gradient boosting machine for prognostic prediction of laryngeal squamous cell carcinoma: a combined analysis of SEER and single-center data [0.03%]
列线图模型比梯度提升机模型更适合预测声门型鳞癌的预后:SEER数据库和单中心数据的联合分析
Difeng Guo,Guanghai Ji,Mengru Jian et al.
Difeng Guo et al.
The incidence of laryngeal squamous cell carcinoma (LSCC) remains persistently high, necessitating accurate prognostic prediction for clinical treatment guidance. By comparing the performance of LSCC models based on the Surveillance, Epidem...
Therapeutic and prognostic value of repeat transurethral resection for high-grade Ta bladder cancer: a propensity score matching analysis [0.03%]
高危Ta期膀胱癌行挽救性经尿道切除的疗效及预后价值:倾向分值匹配分析
Xiaoxi Zhang,Lei Wang,Wenjun Sun et al.
Xiaoxi Zhang et al.
High-grade Ta bladder cancer, although anatomically confined to the mucosa, exhibits aggressive biological behavior with high recurrence rate and progression risks. The role of repeat transurethral resection of bladder tumor (Re-TURBT) in t...
Predictive value of the systemic immune-inflammation index and geriatric nutritional risk index on the efficacy of immunotherapy and survival prognosis in advanced non-small cell lung cancer: a retrospective study [0.03%]
系统免疫炎症指数和老年营养风险指数对晚期非小细胞肺癌免疫治疗疗效及预后预测价值的回顾性研究
Jing Wu,Zhipei Duan,Jing Qian et al.
Jing Wu et al.
Objective: To investigate the predictive value of the systemic immune-inflammation index (SII) and geriatric nutritional risk index (GNRI) for immunotherapy efficacy and survival prognosis in advanced non-small cell lung ...