Characterization and verification of MMP family members as potential biomarkers in kidney clear cell renal carcinoma [0.03%]
MMP家族成员作为肾脏透明细胞肾癌潜在生物标志物的特征和验证
Tianyu Zhao,Xue Li,Mingfeng Li et al.
Tianyu Zhao et al.
Renal cell carcinoma can arise from lesions in the renal epithelium. This particular type of cancer is prevalent in the realm of renal cancers and is associated with an unfavorable prognosis. Among these cases, over 70% are classified as ki...
Chen Xie,Zhijun Wang,Yong Ba et al.
Chen Xie et al.
Chemoresistance is a major therapeutic challenge to prostate cancer and its underlying molecular mechanism is poorly understood. Previously, it has been suggested that bone morphogenetic protein (BMP) signaling is down-regulated during the ...
Targeting the multidrug and toxin extrusion 1 gene (SLC47A1) sensitizes glioma stem cells to temozolomide [0.03%]
靶向多药和毒素外排1基因(SLC47A1)可增强胶质瘤干细胞对替莫唑胺的敏感性
Don Carlo Batara,Sang Wook Park,Hyun-Jin Kim et al.
Don Carlo Batara et al.
Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, with an extremely poor prognosis due to resistance to standard-of-care treatments. Strong evidence suggests that the small population of glioma stem cells (GSCs) cont...
REST-repressed lncRNA LINC01801 induces neuroendocrine differentiation in prostate cancer via transcriptional activation of autophagy [0.03%]
REST抑制的长链非编码RNA LINC01801通过转录激活自噬诱导前列腺癌的神经内分泌分化
Ching-Hsin Chang,Ting-Yu Cheng,Wayne W Yeh et al.
Ching-Hsin Chang et al.
The association between REST reduction and the development of neuroendocrine prostate cancer (NEPC), a novel drug-resistant and lethal variant of castration-resistant prostate cancer (CRPC), is well established. To better understand the mec...
Cancer stem cells of head and neck squamous cell carcinoma; distance towards clinical application; a systematic review of literature [0.03%]
头颈鳞状细胞癌肿瘤干细胞的临床应用距离：综述文献系统的回顾
Qingjia Sun,Xi Chen,Hong Luo et al.
Qingjia Sun et al.
Head and neck squamous cell carcinoma (HNSCC) is the major pathological type of head and neck cancer (HNC). The disease ranks sixth among the most common malignancies worldwide, with an increasing incidence rate yearly. Despite the developm...
PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling [0.03%]
PF-429242通过FOXO1依赖的自噬性细胞死亡和IGFBP1依赖的抗存活信号在肝癌细胞中表现出抗癌活性
Jiunn-Chang Lin,Tsang-Pai Liu,Yan-Bin Chen et al.
Jiunn-Chang Lin et al.
Effective therapies for hepatocellular carcinoma (HCC) are urgently needed, as it is a type of cancer resistant to chemotherapy. Recent evidence showed that PF-429242, a membrane-bound transcription factor site-1 protease (MBTPS1) inhibitor...
Cuproptosis-related lncRNAs as potential biomarkers of AML prognosis and the role of lncRNA HAGLR/miR-326/CDKN2A regulatory axis in AML [0.03%]
与铜死亡相关的长链非编码RNA作为急性髓系白血病预后的潜在生物标志物以及lncRNA HAGLR/miR-326/CDKN2A调节轴在急性髓系白血病中的作用
Ashuai Du,Qinglong Yang,Xinhua Luo
Ashuai Du
Acute myeloblastic leukemia (AML) is the most prevalent form of AML in adults. Despite the availability of various treatment options, including radiotherapy and chemotherapy, many patients fail to respond to treatment or relapse. Copper is ...
Trends and determinants of place of death among Chinese lymphoma patients: a population-based study from 2013-2021 [0.03%]
2013年至2021年中国淋巴瘤患者终末期死亡地点的变化及影响因素：基于人口的队列研究
Xiao-Sheng Ding,Jin-Lei Qi,Wei-Ping Liu et al.
Xiao-Sheng Ding et al.
Limited research exists on factors influencing the place of death (POD) or hospital deaths among lymphoma patients in China, despite the country's significant burden of lymphoid neoplasms. This study aimed to describe the distribution of PO...
Generation and validation of a predictive model for estimating survival among patients with EGFR-mutant non-small cell lung cancer [0.03%]
生成和验证EGFR突变非小细胞肺癌患者生存预测模型及其验证研究
Chien-Yu Lin,Yun-Tse Chou,Po-Lan Su et al.
Chien-Yu Lin et al.
Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have become the standard therapy for patients with EGFR-mutant non-small cell lung cancer (NSCLC), treatment outcomes vary significantly. Previous studies have...
Multimorbidity in people living with and beyond cancer: a scoping review [0.03%]
癌症幸存者和其他癌症患者中多病共存状况的系统综述研究
Tahania A Ahmad,Dipesh P Gopal,Claude Chelala et al.
Tahania A Ahmad et al.
Globally, both cancer incidence and survival are increasing. Early cancer detection and improved treatment means many people with cancer will survive for ten or more years following diagnosis. Multimorbidity, defined as two or more chronic ...