Mechanism of Iminium Salt-Catalyzed C(sp3)-H Amination: Factors Controlling Hydride Transfer versus H-Atom Abstraction [0.03%]
亚胺盐催化C(sp3)―H氨化的机理：氢转移与氢原子抽提的控制因素
Madeline E Rotella,Robert M B Dyer,Michael K Hilinski et al.
Madeline E Rotella et al.
Carbon-nitrogen bonds are extremely prevalent in pharmaceuticals, natural products, and other biologically relevant molecules such as nucleic acids and proteins. Intermolecular amination of C(sp3)-H bonds by catalytic nitrene transfer is a ...
Remote Allylation of Unactivated C(sp3)-H Bonds Triggered by Photogenerated Amidyl Radicals [0.03%]
光生酰基自由基引发的未活化C(sp3)–H键的远程烷基化反应
Bin Xu,Uttam K Tambar
Bin Xu
The allylation reaction is a highly versatile transformation in chemical synthesis. While many elegant direct C(sp2)-H allylation reactions have been developed, the direct allylation of unactivated C(sp3)-H bonds is underdeveloped. By apply...
Liam R Marshall,Oleksii Zozulia,Zsofia Lengyel-Zhand et al.
Liam R Marshall et al.
The field of protein design has grown enormously in the past few decades. In this review we discuss the minimalist approach to design of artificial enzymes, in which protein sequences are created with the minimum number of elements for fold...
pH-Controlled Nanoparticle Catalysts for Highly Selective Tandem Henry Reaction from Mixtures [0.03%]
基于pH值的纳米粒子催化剂在混合底物中的高效亨利反应串联反应中应用研究
Ishani Bose,Yan Zhao
Ishani Bose
Nature has a remarkable ability to perform selective transformation of complex biological mixtures into desired products using enzymatic catalysts. We report the preparation of nanoparticle catalysts through molecular imprinting within cros...
Ni(I)-Catalyzed β,δ-Vinylarylation of γ,δ-Alkenyl α-Cyanocarboxylic Esters via Contraction of Transient Nickellacycles [0.03%]
镍催化γ,δ-烯基α-氰基羧酸酯经瞬时镍环收缩的β,δ-乙烯基芳基化反应
Roshan K Dhungana,Shekhar Kc,Prakash Basnet et al.
Roshan K Dhungana et al.
We disclose a transmetalation-initiated Ni(I)-catalyzed regioselective β,δ-vinylarylation of γ,δ-alkenyl α-cyanocarboxylic esters with vinyl triflates and arylzinc reagents. This reaction proceeds via contraction of six-membered nickel...
Synthesis of 2 H-Chromenes via Hydrazine-Catalyzed Ring-Closing Carbonyl-Olefin Metathesis [0.03%]
hydrazine催化的羰基-烯烃交换环化反应合成2H-色烯化合物
Yunfei Zhang,Janis Jermaks,Samantha N MacMillan et al.
Yunfei Zhang et al.
The catalytic ring-closing carbonyl-olefin metathesis (RCCOM) of O-allyl salicylaldehydes to form 2H-chromenes is described. The method utilizes a [2.2.1]-bicyclic hydrazine catalyst and operates via a [3+2]/retro-[3+2] metathesis manifold....
Dian-Feng Chen,Cameron H Chrisman,Garret M Miyake
Dian-Feng Chen
We report here a mild, safe, and user-friendly bromine radical catalysis system that enables efficient [3 + 2] cycloaddition of diversely substituted vinyl- and ethynylcyclopropanes with a broad range of alkenes, including drug-like molecul...
Oxa- and Azabenzonorbornadienes as Electrophilic Partners under Photoredox/Nickel Dual Catalysis [0.03%]
光氧化还原/镍双催化下噁杂和氮杂苯并环辛二烯作为亲电试剂的研究
Youran Luo,Álvaro Gutiérrez-Bonet,Jennifer K Matsui et al.
Youran Luo et al.
Herein, the introduction of oxa- and azabenzonorbornadienes into photoredox/nickel dual catalysis in a regioselective and diastereoselective transformation is disclosed. The inherent advantages of this dual catalytic system allow the use of...
Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis [0.03%]
捕获二氢叶酸还原酶中的催化质子：对一般酸碱催化的影响
Qun Wan,Brad C Bennett,Troy Wymore et al.
Qun Wan et al.
Acid-base catalysis, which involves one or more proton transfer reactions, is a chemical mechanism commonly employed by many enzymes. The molecular basis for catalysis is often derived from structures determined at the optimal pH for enzyme...
Improved Pd/CeO2 Catalysts for Low-Temperature NO Reduction: Activation of CeO2 Lattice Oxygen by Fe Doping [0.03%]
改进的Pd/CeO2催化剂低温还原NO的研究：Fe掺杂活化CeO2晶格氧
Long Zhang,Giulia Spezzati,Valery Muravev et al.
Long Zhang et al.
Developing better three-way catalysts with improved low-temperature performance is essential for cold start emission control. Density functional theory in combination with microkinetics simulations is used to predict reactivity of CO/NO/H2 ...