Stephen Strom
Stephen Strom
Monitoring of Liver Cell Transplantation in a Preclinical Swine Model Using Magnetic Resonance Imaging [0.03%]
磁共振成像在临床前猪肝细胞移植模型中的应用监视
Nathanael Raschzok,Ulf Teichgräber,Nils Billecke et al.
Nathanael Raschzok et al.
Liver cell transplantation (LCT) is a promising treatment approach for certain liver diseases, but clinical implementation requires methods for noninvasive follow-up. Labeling with superparamagnetic iron oxide particles can enable the detec...
Autografting of Renal Progenitor Cells Ameliorates Kidney Damage in Experimental Model of Pyelonephritis [0.03%]
自体移植肾脏祖细胞改善肾输尿管连接部梗阻模型中的肾损害
Abdol-Mohammad Kajbafzadeh,Azadeh Elmi,Saman Shafaat Talab et al.
Abdol-Mohammad Kajbafzadeh et al.
Current therapies for pyelonephritic renal damage have severe limitations; stem cells may offer an exciting potential in regenerating nephrology. We aimed to investigate the feasibility of direct intrarenal injection of autologous renal pro...
Neuroprotective and Angiogenic Effects of Bone Marrow Transplantation Combined With Granulocyte Colony-Stimulating Factor in a Mouse Model of Amyotrophic Lateral Sclerosis [0.03%]
骨髓移植联合粒细胞集落刺激因子在渐冻症小鼠模型中的神经保护和促血管生成作用
Yasuyuki Ohta,Makiko Nagai,Kazunori Miyazaki et al.
Yasuyuki Ohta et al.
Bone marrow (BM) cells from amyotrophic lateral sclerosis (ALS) patients show significantly reduced expression of several neurotrophic factors. Monotherapy with either wild-type (WT) BM transplantation (BMT) or granulocyte colony-stimulatin...
Early Immunomodulation by Intravenously Transplanted Mesenchymal Stem Cells Promotes Functional Recovery in Spinal Cord Injured Rats [0.03%]
静脉移植间充质干细胞早期免疫调控促进脊髓损伤大鼠功能恢复
Jung Hwa Seo,In Keun Jang,Hyongbum Kim et al.
Jung Hwa Seo et al.
Although intravenous administration of mesenchymal stem cells (MSCs) can enhance functional recovery after spinal cord injury (SCI), the underlying mechanisms have to be elucidated. In this study, we explored the mechanisms for functional r...
Mesenchymal Stromal Cells as a Therapeutic Strategy to Support Islet Transplantation in Type 1 Diabetes Mellitus [0.03%]
间充质基质细胞在1型糖尿病胰岛移植中的治疗策略作用
Sarah A Busch,Saskia T J van Crutchen,Robert J Deans et al.
Sarah A Busch et al.
Type 1 diabetes is an autoimmune disorder that leads to destruction of pancreatic β islet cells and is a growing global health issue. While insulin replacement remains the standard therapy for type 1 diabetes, exogenous insulin does not mi...
Upregulation of Adipogenesis and Chondrogenesis in MSC Serum-Free Culture [0.03%]
无血清培养体系诱导间充质干细胞向脂肪和软骨方向分化的机制研究
Saey Tuan Barnabas Ho,Vivek Madhukar Tanavde,James Hoi Hui et al.
Saey Tuan Barnabas Ho et al.
Serum-free media have been shown to be effective in the expansion of mesenchymal stem cells (MSCs). However, the effects may go beyond cell expansion as the differentiation potentials of the cells may be modified, thus influencing their eff...
Maria Giovanna Francipane,Melchiorre Cervello,Giovanni Battista Vizzini et al.
Maria Giovanna Francipane et al.
The severe shortage of deceased donor organs has driven a search for alternative methods of treating liver failure. In this context, cell-based regenerative medicine is emerging as a promising interdisciplinary field of tissue repair and re...
Prospects for Induced Phiripotent Stem Cell-Derived Hepatocytes in Cell Therapy [0.03%]
诱导多能干细胞来源肝细胞的细胞治疗前景
Masaya Iwamuro,Javed M Shahid,Kazuhide Yamamoto et al.
Masaya Iwamuro et al.
Induced pluripotent stem (iPS) cells, first established in 2006, have the same characteristics of self-renew-ability and pluripotency as embryonic stem (ES) cells. iPS cells are inducible from patient-specific somatic cells; therefore, they...
Liver Cell Culture Devices [0.03%]
肝细胞培养装置
B Andria,A Bracco,G Cirino et al.
B Andria et al.
In the last 15 years many different liver cell culture devices, consisting of functional liver cells and artificial materials, have been developed. They have been devised for numerous different applications, such as temporary organ replacem...