Construction of Artificial Hepatic Lobule-Like Spheroids on a Three-Dimensional Culture Device [0.03%]
一种三维培养装置用于构建人工肝小叶类球体
Shin Enosawa,Yoshitaka Miyamoto,Hisayo Kubota et al.
Shin Enosawa et al.
One major purpose of cell culture is the reconstruction of physiological structures. Using bovine aortic epithelium cell line HH (JCRB0099) as feeder cells and rat primary hepatocytes, we constructed hepatic lobule-like spheroids on a cell ...
Consideration of a Safe Protocol for Hepatocyte Transplantation Using Infantile Pigs [0.03%]
关于使用幼年猪进行肝细胞移植的安全性协议的考虑
Shin Enosawa,Wenji Yuan,Masaharu Douzen et al.
Shin Enosawa et al.
Hepatocyte transplantation is hoped to be an alternative treatment to certain cases of liver transplantation. The most promising indication is for congenital metabolic diseases, especially in infants. To establish a safe protocol for hepato...
In Vivo Bioimaging Rats for Translational Research in Cell and Tissue Transplantation [0.03%]
用于细胞和组织移植的转化研究的活体成像大鼠
Takumi Teratani,Eiji Kobayashi
Takumi Teratani
The rat is an excellent cell transplantation model. In accordance with the innovative development of in vivo bioimaging technology, over the last decade we have been developing an engineered rat system based on transgenic technology and hav...
Hirofumi Noguchi
Hirofumi Noguchi
Aggregation of Engineered Human β-Cells Into Pseudoislets: Insulin Secretion and Gene Expression Profile in Normoxic and Hypoxic Milieu [0.03%]
工程化的人β细胞聚集成伪胰岛：正常氧浓度和低氧条件下胰岛素的分泌及基因表达谱
Marie-José Lecomte,Séverine Pechberty,Cécile Machado et al.
Marie-José Lecomte et al.
Innovative treatments to cure type 1 diabetes are being actively researched. Among the different strategies, the replacement of β-cells has given promising results. Classically, islets from cadaveric donors are transplanted into diabetic p...
Stability Enhancement Using Hyaluronic Acid Gels for Delivery of Human Fetal Progenitor Tenocytes [0.03%]
透明质酸凝胶增强人胎儿前体腱细胞移植的稳定性
A Grognuz,C Scaletta,A Farron et al.
A Grognuz et al.
Tendon afflictions are very common, and their negative impact is high both at the workplace and in leisure activities. Tendinopathies are increasing in prevalence and can lead to tendon ruptures, where healing is a long process with outcome...
αSMA Expression in Large Colonies of Colony-Forming Units-Fibroblast as an Early Predictor of Bone Marrow MSC Expandability [0.03%]
克隆形成单位-成纤维细胞大菌落中αSMA表达作为骨髓MSC扩增能力的早期预测标志
Irina Aizman,William S Holland,Cher Yang et al.
Irina Aizman et al.
Clinical applications of mesenchymal stromal cells (MSCs) require the manufacture of large cell lots, which involves multiple passages for cell expansion and sometimes genetic modification. MSCs from various sources, including bone marrow (...
Allogeneic Mesenchymal Stem Cell Transplantation in Dogs With Keratoconjunctivitis Sicca [0.03%]
用于治疗干眼症犬的同种异体间充质干细胞移植
Maura K W Bittencourt,Michele A Barros,João Flávio P Martins et al.
Maura K W Bittencourt et al.
Keratoconjunctivitis sicca (KCS) is a dysfunction in tear production associated with clinical signs, which include conjunctival hyperemia, ocular discharge, discomfort, pain, and, eventually, corneal vascularization and pigmentation. Immuno...
Validation of Islet Transport From a Geographically Distant Isolation Center Enabling Equitable Access and National Health Service Funding of a Clinical Islet Transplant Program for England [0.03%]
异地来源胰岛运输的验证以实现临床胰岛移植项目的公平准入及英国国家医疗服务体系资助
Ali Aldibbiat,Guo Cai Huang,Min Zhao et al.
Ali Aldibbiat et al.
Islet transplantation has become established as a successful treatment for type 1 diabetes complicated by recurrent severe hypoglycemia. In the UK access has been limited to a few centrally located units. Our goal was to validate a quality-...
Resident Endothelial Progenitor Cells From Human Placenta Have Greater Vasculogenic Potential Than Circulating Endothelial Progenitor Cells From Umbilical Cord Blood [0.03%]
人胎盘的居民内皮祖细胞比脐带血循环内皮祖细胞具有更强的血管生成潜能
Brian M Rapp,M Reza Saadatzedeh,Richard H Ofstein et al.
Brian M Rapp et al.
Endothelial colony-forming cells (ECFCs) isolated from umbilical cord blood (CBECFCs) are highly proliferative and form blood vessels in vivo. The purpose of this investigation was to isolate and characterize a population of resident ECFCs ...