A Comparison of Pancreatic Islet Purification using Iodixanol with University of Wisconsin Solution and with Na-Lactobionate and Histidine Solution [0.03%]
碘ixinol与UW溶液及Na-乳泰+组氨酸溶液分离人胰岛的比较研究
Yoshiki Nakashima,Chika Miyagi-Shiohira,Nana Ebi et al.
Yoshiki Nakashima et al.
Purification of pancreatic islets is an important step in islet isolation for islet transplantation. In this study, to investigate how a solution composed mainly of Na-lactobionate and histidine (HL) influences the purification of islets, i...
Jessica N Mazerik,Steven Becker,Paul A Sieving
Jessica N Mazerik
Across scientific disciplines, 3-D organoid culture systems offer platforms to integrate basic research findings with clinical care. The National Eye Institute mounted a $1.1 million 3-D Retina Organoid Challenge. Organoids developed throug...
Patrick Narbonne
Patrick Narbonne
During development, stem cells generate all of the differentiated cells that populate our tissues and organs. Stem cells are also responsible for tissue turnover and repair in adults, and as such, they hold tremendous promise for regenerati...
Pediatric Arterial Ischemic Stroke: Clinical Presentation, Risk Factors, and Pediatric NIH Stroke Scale in a Series of Chilean Patients [0.03%]
儿童动脉性脑梗死的临床表现、危险因素及儿科NIH卒中量表在一组智利患者中的应用
María José Hidalgo,Daniela Muñoz,Fernanda Balut et al.
María José Hidalgo et al.
Stroke is an important cause of morbidity and mortality in children. Clinical presentation is diverse, and multiple risk factors have been described. The aim of this retrospective study is to describe the clinical presentation, risk factors...
Long-Term Effects of Fibrin Conduit with Human Mesenchymal Stem Cells and Immunosuppression after Peripheral Nerve Repair in a Xenogenic Model [0.03%]
携带人骨髓间充质干细胞的纤维蛋白导管联合免疫抑制在异种周围神经移植中的长期影响研究
Aleksandra M McGrath,Maria Brohlin,Rebecca Wiberg et al.
Aleksandra M McGrath et al.
Introduction: Previously we showed that a fibrin glue conduit with human mesenchymal stem cells (hMSCs) and cyclosporine A (CsA) enhanced early nerve regeneration. In this study long term effects of this conduit are inves...
Airway Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Reverses Bronchopulmonary Dysplasia Superimposed with Acute Respiratory Distress Syndrome in an Infant [0.03%]
骨髓间充质干细胞经气道递送可逆转婴儿急性呼吸窘迫综合征合并支气管肺发育不良症状
Hsin-Chia Lin,Ching-Chia Wang,Heng-Wen Chou et al.
Hsin-Chia Lin et al.
Bronchopulmonary dysplasia (BPD), a disease affecting extremely premature infants, results from the disruption of normal pulmonary vascular and alveolar growth. Currently, there is no specific effective treatment. We report a case of a 10-m...
John E Piletz,Jennifer Drivon,John Eisenga et al.
John E Piletz et al.
Safety concerns over cell-derived pharmaceutical products being manufactured in supplements of fetal bovine serum (FBS) have ignited pleas to replace FBS. Herein, four newly marketed alternatives to FBS were compared: a xeno-free product ca...
Takako Tsugata,Naruo Nikoh,Tatsuya Kin et al.
Takako Tsugata et al.
The low efficiency of in vitro differentiation of human embryonic stem cells (hESCs) or human-induced pluripotent stem cells (iPSCs) into insulin-producing cells is a crucial hurdle for the clinical implementation of human pluripotent stem ...
The Development of Cancer through the Transient Overexpression of Reprogramming Factors [0.03%]
通过瞬时过度表达重编程因子诱发癌症的发展
Chika Miyagi-Shiohira,Yoshiki Nakashima,Naoya Kobayashi et al.
Chika Miyagi-Shiohira et al.
Although induced pluripotent stem (iPS) cells have significant implications for overcoming most of the ethical issues associated with embryonic stem cells, several issues related to the use of iPS cells in clinical applications remain unres...
Cell Deposition Microchip with Micropipette Control over Liquid Interface Motion [0.03%]
具有微吸管控制液面运动的细胞打印芯片
Daisuke Onoshima,Yuya Hattori,Hiroshi Yukawa et al.
Daisuke Onoshima et al.
Positioning single cells on a solid surface is a crucial technique for understanding the cellular functions and cell-cell interactions in cell culture assays. We developed a microfluidic chip for depositing single cells in microwells using ...