Critical Shifts in Cerebral White Matter Lipid Profiles After Ischemic-Reperfusion Brain Injury in Fetal Sheep as Demonstrated by the Positive Ion Mode MALDI-Mass Spectrometry [0.03%]
MALDI-质量光谱法显示的胎儿羊缺血再灌注脑损伤后大脑白质脂类特性的关键变化
Suzanne M de la Monte,Gina M Gallucci,Amy Lin et al.
Suzanne M de la Monte et al.
Ischemic-reperfusion (I/R) injury to cerebral white matter during the perinatal period leads to long-term cognitive and motor disabilities in children. Immature white matter oligodendrocytes are especially vulnerable to metabolic insults su...
Cryopreserved Alginate-Encapsulated Islets Can Restore Euglycemia in a Diabetic Animal Model Better than Cryopreserved Non-encapsulated Islets [0.03%]
与未包封的冷冻胰岛相比，冷冻保存的海藻酸盐包封胰岛可以更好地恢复糖尿病动物模型中的血糖正常水平
Greg G Kojayan,Antonio Flores,Shiri Li et al.
Greg G Kojayan et al.
Islet transplantation has been shown to restore normoglycemia clinically. One of the current limitations to the widespread clinical use of islet transplantation is culturing and preserving more than 1 million islet equivalents in preparatio...
A Case of Acute Lymphocytic Leukaemia with t(3;13) and Central Nervous System Leukemia after Allogenic Cord Blood Transplantation [0.03%]
allo-HSCT后发生中枢神经系统白血病的急淋白血病患者伴有t(3;13)染色体异常病例报告
Xiaofan Li,Yaqun Hong,Jiafu Huang et al.
Xiaofan Li et al.
Background: Acute lymphoblastic leukemia (ALL) is a neoplastic cancer characterized by clonal expansion of leukemic cells in lymph organs and bone marrow. Lots of kinds of different chromosomal translocations can be found...
Sandeep Satapathy,Chanchal Kumar,Roshan Kumar Singh
Sandeep Satapathy
The tumor microenvironment can be realistically viewed as an active battle ground between the host immune system and the growing tumor cells. This reactive space surrounding the tumor possesses several possibilities and facilitates the prog...
Unsurpassed Intrahepatic Islet Engraftment - the Quest for New Sites for Beta Cell Replacement [0.03%]
无与伦比的肝内胰岛移植-寻找新的β细胞替代移植位点的研究
Hanna Liljebäck,Daniel Espes,Per-Ola Carlsson
Hanna Liljebäck
The liver is currently the site of choice for clinical islet transplantation, even though many alternative implantation sites have lately been proposed as more ideal for graft survival. The suggested sites, for example intramuscular space, ...
Bone Grafts, Bone Substitutes and Regenerative Medicine Acceptance for the Management of Bone Defects Among French Population: Issues about Ethics, Religion or Fear? [0.03%]
关于骨移植、骨替代品和再生医学在法国人群中的接受度——伦理、宗教或恐惧的问题？
Damien Offner,Gabriel Fernandez de Grado,Inès Meisels et al.
Damien Offner et al.
Several techniques exist to manage bone defects in patients: bone grafts (autograft, allograft, xenograft), use of synthetic bone substitutes, or use of the products of bone regenerative medicine. Studies generally focus on their efficacy, ...
Mitochondrial Respiratory Capacity is Restored in Hibernating Cardiomyocytes Following Co-Culture with Mesenchymal Stem Cells [0.03%]
间充质干细胞联合培养可恢复冬眠心肌细胞线粒体呼吸能力
Laura L Hocum Stone,Erin Chappuis,Maribel Marquez et al.
Laura L Hocum Stone et al.
Hibernating myocardium is a subset of ischemic cardiac disease characterized by viable but dysfunctional tissue. Standard treatment for hibernating myocardium is coronary artery bypass graft, which reduces arrhythmias and improves survival ...
Approval of First CAR-Ts: Have we Solved all Hurdles for ATMPs? [0.03%]
首个CAR-T产品获批：我们解决了先进疗法药物的所有障碍吗？
Diane Seimetz,Karl Heller,Jan Richter
Diane Seimetz
T cells are known as the most potent killer cells of the immune system, designed by nature to prevent unwanted challenges. The first class of therapeutic products harnessing the power of T cells for target-specific treatment of oncological ...
Risk Factors for Perinatal Arterial Ischemic Stroke: A Case-Control Study [0.03%]
围生期动脉性缺血性脑卒中的危险因素研究：病例对照研究
Daniela Munoz,María José Hidalgo,Fernanda Balut et al.
Daniela Munoz et al.
Introduction: Arterial ischemic stroke in newborns is an important cause of neonatal morbidity and mortality. Its pathophysiology and associated risk factors are not yet clearly understood and defined. ...
Comparison of Tissue Loading Before and After the Creation of a Continuous Density Gradient in Porcine Islet Purification [0.03%]
猪胰岛纯化前后连续密度梯度创建的组织负荷比较研究
Chika Miyagi-Shiohira,Yoshiki Nakashima,Nana Ebi et al.
Chika Miyagi-Shiohira et al.
The purification step is one of the most important and difficult procedures in islet isolation for pancreatic islet transplantation. We previously reported that a purification method using large plastic bottles effectively achieved a high y...