Rho-guanine nucleotide exchange factors during development: Force is nothing without control [0.03%]
发育中的_rho_鸟苷酸交换因子:光有关节无弹力则寸步难行
Shai Mulinari,Udo Häcker
Shai Mulinari
The development of multicellular organisms is associated with extensive rearrangements of tissues and cell sheets. The driving force for these rearrangements is generated mostly by the actin cytoskeleton. In order to permit the reproducible...
Adrienne D Cox,Channing J Der
Adrienne D Cox
Although the roots of Ras sprouted from the rich history of retrovirus research, it was the discovery of mutationally activated RAS genes in human cancer in 1982 that stimulated an intensive research effort to understand Ras protein structu...
Michael J Williams,Klemens Rottner
Michael J Williams
Hisashi Tatebe,Kazuhiro Shiozaki
Hisashi Tatebe
In diverse eukaryotic species from yeast to human, TOR (Target Of Rapamycin) protein kinase operates in signaling pathways that link extracellular stimuli to the control of cell growth and metabolism. TOR kinase functions in two distinct pr...