Disruption of the Fibroinflammatory Loop: A Therapeutic Strategy for Cardiac Fibrosis in Non-Ischemic Cardiomyopathy [0.03%]
非缺血性心肌病心脏纤维化的治疗策略:破坏纤维炎症循环
Hongyu Qiu,Inna P Gladysheva
Hongyu Qiu
In non-ischemic cardiomyopathy, inflammation is closely associated with cardiac fibrosis, which significantly contributes to adverse outcomes and promotes heart failure (HF). Recent mechanistic studies have demonstrated that interactions be...
Diagnostic and Prognostic Value of Arterial Blood Gas and Electrolyte Analyses in Heart Failure [0.03%]
动脉血气和电解质分析在心力衰竭中的诊断及预后价值
Nardi Tetaj,Andrea Segreti,Francesco Piccirillo et al.
Nardi Tetaj et al.
Heart failure (HF) is a multifaceted clinical syndrome that frequently precipitates disturbances in perfusion, ventilation, and metabolic regulation, all of which are rapidly detectable through arterial blood gas (ABG) analysis. Meanwhile, ...
Representation of Women in Atrial Fibrillation Clinical Trials: A Systematic Review [0.03%]
房颤临床试验中女性的代表性:系统性综述
Ramzi Ibrahim,Hoang Nhat Pham,Christopher Kanaan et al.
Ramzi Ibrahim et al.
Background: Disparities exist in the representation of genders in cardiovascular clinical trials. Atrial fibrillation (AF) is associated with significant morbidity and mortality; however, understanding regarding the repre...
Synergistic Cardiopulmonary Protection of Endothelin Receptor Antagonists Combined With Soluble Guanylate Cyclase Agonists in High-Risk Coronary Syndrome With Pulmonary Hypertension [0.03%]
内皮素受体拮抗剂联合可溶性鸟苷酸环化酶激动剂对冠状动脉综合征合并肺动脉高压的协同心肺保护作用
Liyue Zhao,Xinli Pang
Liyue Zhao
Background: The prognosis and long-term survival of high-risk coronary syndrome patients with pulmonary hypertension (PH) remain unsatisfactory, and limited research has evaluated the synergistic therapeutic effects of en...
Molecular Mechanisms and Therapeutic Strategies in Heart Failure Due to Dystrophin Deficiency: A Comprehensive Review [0.03%]
杜氏肌营养不良相关心力衰竭的分子机制和治疗策略:综述文章
Wanqian Yu,Wang Wang,Fan Luo et al.
Wanqian Yu et al.
Dystrophin deficiency is the core pathological feature of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Indeed, a deficiency in dystrophin results in the progressive degeneration of skeletal muscle and severely comp...
Biomarker-Guided Versus Clinically Guided Management Strategies for Heart Failure: A Systematic Review and Meta-Analysis [0.03%]
基于生物标志物指导与临床指导的心力衰竭管理策略的系统评价和meta分析
Hao Zhou,Ting Liu,Fuxia Lan et al.
Hao Zhou et al.
Background: The clinical value of B-type natriuretic peptide (BNP) or N-terminal pro-B-type natriuretic peptide (NT-proBNP)-guided therapy for improving outcomes in patients with heart failure (HF) remains controversial. ...
ZNF460 Promotes GSDME-Driven Pyroptosis via PKM2 Transcriptional Activation in Aortic Dissection [0.03%]
ZNF460通过PKM2转录激活促进主动脉夹层中GSDME驱动的pyroptosis
Quanlin Yang,Xin Shao,Zihe Zheng et al.
Quanlin Yang et al.
Background: Aortic dissection (AD) is a cardiovascular emergency with high mortality; however, the underlying molecular pathophysiology of AD remains incompletely understood. Pyroptosis, a proinflammatory form of programm...
Percutaneous Closure of Patent Foramen Ovale is Associated With Improvement of Migraine [0.03%]
卵圆孔未闭封堵与偏头痛改善有关
Xiao-Ming Ge,Kang-Ning Han,Fei Gao et al.
Xiao-Ming Ge et al.
Background: Patent foramen ovale (PFO) is the most common congenital heart defect and has been linked to migraines; however, the relationship between PFO and migraine remains controversial. This study aimed to evaluate wh...
Concomitant Intra-Aortic Balloon Pump Throughout Extracorporeal Cardiopulmonary Resuscitation: A Meta-Analysis of Cohorts [0.03%]
体外心肺复苏期间同时使用主动脉内球囊泵的荟萃分析:队列研究
Huiruo Liu,Liangshan Wang,Hongfu Fu et al.
Huiruo Liu et al.
Background: Inconsistent reports exist regarding the efficacy of using a concomitant intra-aortic balloon pump (IABP) among cardiac arrest (CA) patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR). Thus...
Sex-Specific Heart Rate Variability Associations With Vitamin B12, Folate, and Iron Status [0.03%]
维生素B12、叶酸和铁状态与心率变异性之间的性别差异性关联研究
Mehmet Özyaşar,Selçuk Öztürk,Tolga Memioğlu et al.
Mehmet Özyaşar et al.
Background: The sex-specific impact of micronutrient status on heart rate variability (HRV) in adults presenting with palpitations to cardiology outpatient clinics remains unclear. Thus, this study aimed to assess the dem...