Implication for long-term hypothermia on degradation of interleukin-8 mRNA in endothelial cells stimulated with lipopolysaccharides [0.03%]
长期低温对脂多糖刺激的内皮细胞中白介素-8mRNA降解的影响研究
Atsushi Sakurai,Kosaku Kinoshita,Makoto Furukawa et al.
Atsushi Sakurai et al.
This experimental study investigated the effects of long-term hypothermia on the production of interleukin (IL)-8 protein and its mRNA expression in endothelial cells stimulated by lipopolysaccharides (LPS). Human umbilical vein endothelial...
Induction of a prolonged hypothermic state by drug-induced reduction in the thermoregulatory set-point [0.03%]
通过药物诱导降低体温调节设定点来诱发长时间低温状态
Laurence M Katz,Jonathan E Frank,Gerald McGwin Jr et al.
Laurence M Katz et al.
Background: The marked improvement in outcome following induction of hypothermia after cardiac arrest has spurred the search for better methods to induce cooling. A regulated decrease in core temperature mediated by a dru...
Effects of different fluid regimes and desmopressin on uncontrolled hemorrhage during hypothermia in the rat [0.03%]
不同液体治疗方案及去氨加压素在大鼠低温诱导的难控出血中的效果研究
Göran Heinius,Anders Sondén,Robert G Hahn
Göran Heinius
Resuscitation with large volumes of crystalloids during traumatic hemorrhagic shock might increase the mortality by inducing rebleeding. However, few studies have addressed this problem during hypothermic conditions. Sixty-eight Sprague-Daw...
Protracted Tyrosine Phosphorylation of the Glutamate Receptor Subunit NR2 in the Rat Hippocampus Following Transient Cerebral Ischemia is Prevented by Intra-Ischemic Hypothermia [0.03%]
短暂脑缺血后大鼠海马区NMDA受体NR2亚单位的酪氨酸磷酸化状态持续延长及缺血中轻度降低体温对其影响
Bingren Hu,Hans Friberg,Tadeusz Wieloch
Bingren Hu
Changes in the dynamic interactions of macromolecules in cell membranes appear to underlie the robust neuroprotective effect of hypothermia against selective neuronal degeneration in the CA1 region of the rat hippocampus after transient cer...
Donald W Marion,Daniel I Sessler,W Dalton Dietrich
Donald W Marion
The Use of Hypothermia Therapy in Traumatic Ischemic / Reperfusional Brain Injury: Review of the Literatures [0.03%]
创伤性脑缺血/再灌注损伤亚低温治疗的临床应用及机制研究进展
Shoji Yokobori,Janek Frantzen,Ross Bullock et al.
Shoji Yokobori et al.
Therapeutic mild hypothermia has been used widely in brain injury. It has evaluated in numerous clinical trials, and there is strong evidence for the use of hypothermia in treating patients with several types of ischemic / reperfusional (I/...
THE EFFECTS OF POSTTRAUMATIC HYPOTHERMIA ON DIFFUSE AXONAL INJURY FOLLOWING PARASAGGITAL FLUID PERCUSSION BRAIN INJURY IN RATS [0.03%]
创伤性低体温对幕上脑液冲击伤弥漫性轴索损伤的影响
Helen M Bramlett,W Dalton Dietrich
Helen M Bramlett
Previous investigations have demonstrated the beneficial effects of mild hypothermia following different types of traumatic brain injury (TBI). In some models, early cooling following TBI has been shown to reduce the frequency of axonal dam...
OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA [0.03%]
轻度低温对脑外伤后少突胶质细胞脆弱性的影响：大鼠模型研究
George Lotocki,Juan de Rivero Vaccari,Ofelia Alonso et al.
George Lotocki et al.
The purpose of this study was to document patterns of oligodendrocyte vulnerability to TBI and determine whether posttraumatic hypothermia prevents oligodendrocyte cell loss. Sprague Dawley rats underwent moderate fluid percussion brain inj...