Therapeutic Hypothermia in Children and Adults with Severe Traumatic Brain Injury [0.03%]
儿童和成人严重创伤性脑损伤的治疗性低温疗法
Anna Sandestig,Bertil Romner,Per-Olof Grände
Anna Sandestig
Great expectations have been raised about neuroprotection of therapeutic hypothermia in patients with traumatic brain injury (TBI) by analogy with its effects after heart arrest, neonatal asphyxia, and drowning in cold water. The aim of thi...
John Povlishock,Shoji Yokobori,Yasuhiro Kuroda et al.
John Povlishock et al.
Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke [0.03%]
触发性表达于髓系细胞-2与缺血性卒中低温神经保护相关
Masahito Kawabori,Masaaki Hokari,Zhen Zheng et al.
Masahito Kawabori et al.
Hypothermia is neuroprotective against many acute neurological insults, including ischemic stroke. We and others have previously shown that protection by hypothermia is partially associated with an anti-inflammatory effect. Phagocytes are t...
Limitations of Mild, Moderate, and Profound Hypothermia in Protecting Developing Hippocampal Neurons After Simulated Ischemia [0.03%]
模拟缺血后轻度、中度和重度降低体温对发育中的海马神经元的保护作用的局限性
Maren Gregersen,Deok Hee Lee,Pablo Gabatto et al.
Maren Gregersen et al.
Mild hypothermia (33°C-34°C) after cerebral ischemia in intact animals or ischemia-like conditions in vitro reduces neuron death. However, it is now clear that more profound hypothermia or delayed hypothermia may not provide significant p...
Jaron D Raper,Henry E Wang
Jaron D Raper
While commonly described, no studies have characterized cold-induced diuresis or rewarm anti-diuresis occurring during the delivery of therapeutic hypothermia (TH). We sought to determine urine output changes during the provision of postcar...
Moderator Justin Lundbye,Participants Eric James Zoog,Robert Silbergleit et al.
Moderator Justin Lundbye et al.
Bullous Lesions After Use of a Commercial Therapeutic Hypothermia Temperature Management System: A Possible Burn Injury? [0.03%]
商用治疗性低体温管理系统使用后的水疱样皮损：烧伤所致？
Henry E Wang,James M Wells,Dana V Rizk
Henry E Wang
Therapeutic hypothermia (TH) is a novel technique for improving the likelihood of survival with good neurologic outcome after cardiopulmonary arrest. While commercial temperature management systems (TMS) are intended to facilitate cooling o...
Relative Higher Hematocrit Attenuates the Cerebral Excitatory Amino Acid Elevation Induced by Deep Hypothermic Circulatory Arrest in Rats [0.03%]
相对较高血红蛋白浓度减轻深低温体外循环引起的大鼠脑内兴奋性氨基酸升高
Meijuan Zhu,Yanhua Zhao,Yongjun Zheng et al.
Meijuan Zhu et al.
Hemodilution is a commonly used technique in cardiopulmonary bypass (CPB) and deep hypothermic circulation arrest (DHCA). Our previous study showed that lower hematocrit aggravated the brain injury after DCHA. Because the excitatory amino a...
Effects of Mild Hypothermia Treatment on Rat Hippocampal β-Amyloid Expression Following Traumatic Brain Injury [0.03%]
轻度低温处理对创伤性脑损伤后大鼠海马β淀粉样蛋白表达的影响
Shi-Xiang Cheng,Sai Zhang,Hong-Tao Sun et al.
Shi-Xiang Cheng et al.
Previous studies have reported that mild induced hypothermia (MIH) treatment has positive effects on traumatic brain injury (TBI) outcomes, which have recently been linked to β-amyloid (Aβ)-induced secondary brain injury (SBI) extent in h...
Usefulness of Deep Hypothermic Circulatory Arrest and Regional Cerebral Perfusion in Children [0.03%]
儿童深低温停循环和脑局部灌注的临床价值
Zheng Guo,Ren-Jie Hu,De-Ming Zhu et al.
Zheng Guo et al.
To compare the safety and usefulness of deep hypothermic circulatory arrest (DHCA) and regional cerebral perfusion (RCP) during pediatric open heart surgery. Between January 1, 2004 and September 30, 2012, 1250 children with congenital card...