Unique brain region-dependent cytokine signatures after prolonged hypothermic cardiac arrest in rats [0.03%]
长时间低温心脏停搏后大鼠不同脑区细胞因子特征分布
Tomas Drabek,Caleb D Wilson,Andreas Janata et al.
Tomas Drabek et al.
We previously showed that prolonged cardiac arrest (CA) produces neuronal death with microglial proliferation. Microglial proliferation, but not neuronal death, was attenuated by deeper hypothermia. Microglia are reportedly a major source o...
Kees Polderman,Niklas Nielsen,Carmelo Graffagnino et al.
Kees Polderman et al.
Localized hypothermia aggravates bleeding in the collagenase model of intracerebral hemorrhage [0.03%]
局部降温和胶原酶诱导的脑内血肿出血的关系
Roseleen F John,Michael R Williamson,Kristen Dietrich et al.
Roseleen F John et al.
Animal studies testing whether therapeutic hypothermia is neuroprotective after intracerebral hemorrhage (ICH) have been inconclusive. In rodents, ICH is often produced in the striatum by infusing collagenase, which causes prolonged hemorrh...
Temperature control during therapeutic hypothermia for newborn encephalopathy using different Blanketrol devices [0.03%]
不同Blanketrol设备治疗新生儿脑病诱导低温疗法中的温度控制效果研究
Abbot R Laptook,Howard Kilbride,Edward Shepherd et al.
Abbot R Laptook et al.
Therapeutic hypothermia improves the survival and neurodevelopmental outcome of infants with newborn encephalopathy of a hypoxic-ischemic origin. The NICHD Neonatal Research Network (NRN) Whole Body Cooling trial used the Cincinnati Sub-Zer...
Randomized Controlled Trial
Therapeutic hypothermia and temperature management. 2014 Dec;4(4):193-200. DOI:10.1089/ther.2014.0009 2014
Hypothermia in the setting of experimental acute myocardial infarction: a comprehensive review [0.03%]
实验性急性心肌梗死时低体温症的全面回顾
Michael J Herring,Sharon L Hale,Wangde Dai et al.
Michael J Herring et al.
A door-to-balloon time of less than 90 minutes is the gold standard for reperfusion therapy to treat acute myocardial infarction (MI). Because 30-day mortality remains ∼ 10%, new methods must be cultivated to limit myocardial injury. Thera...
The baby cooling project of Japan to implement evidence-based neonatal cooling [0.03%]
日本基于证据的新生儿降温项目的婴儿冷却工程
Osuke Iwata,Toshiki Takenouchi,Sachiko Iwata et al.
Osuke Iwata et al.
Therapeutic hypothermia was first recommended as a standard of care by international guidelines in 2010. However, at that time, the number of centers capable of providing standard cooling was limited even in Japan. The aim of this project w...
Magnesium depletion in patients treated with therapeutic hypothermia after cardiac arrest [0.03%]
心肺复苏后低温治疗患者的镁缺乏症
Maryann Mazer-Amirshahi,Sarah M Perman,Anne V Grossestreuer et al.
Maryann Mazer-Amirshahi et al.
Magnesium (Mg(2+)) depletion can have detrimental effects in postcardiac arrest patients through multiple potential mechanisms. Therapeutic hypothermia (TH) produces a Mg(2+) diuresis, but the effects of postcardiac arrest TH on serum Mg(2+...
Moderate hypothermia for intradural spinal tumor resection: a cohort comparison and feasibility study [0.03%]
中度低温用于脊髓内肿瘤切除术的队列比较和可行性研究
Jeremiah N Johnson,Matthew D Cummock,Allan D Levi et al.
Jeremiah N Johnson et al.
To evaluate the safety and feasibility of modest hypothermia as a potential strategy for intraoperative neuroprotection during the removal of intradural spinal tumors. A retrospective review was performed for two groups of patients of a sin...
W Dalton Dietrich
W Dalton Dietrich
Full neurologic recovery and return of spontaneous circulation following prolonged cardiac arrest facilitated by percutaneous left ventricular assist device [0.03%]
经皮心脏辅助装置支持下成功救治长时间心搏骤停后恢复自主循环及神志完全恢复的病例报告
Michael Heidlebaugh,Michael C Kurz,Carman L Turkelson et al.
Michael Heidlebaugh et al.
Sudden cardiac arrest is associated with high early mortality, which is largely related to postcardiac arrest syndrome characterized by an acute but often transient decrease in left ventricular (LV) function. The stunned LV provides poor ca...