Therapeutic Hypothermia Reduces Intracranial Pressure and Partial Brain Oxygen Tension in Patients with Severe Traumatic Brain Injury: Preliminary Data from the Eurotherm3235 Trial [0.03%]
治疗性低温可以降低严重颅脑损伤患者颅内压及局部脑氧张力：来自Eurotherm3235试验的初步数据
Liam M C Flynn,Jonathan Rhodes,Peter J D Andrews
Liam M C Flynn
Traumatic brain injury (TBI) is a significant cause of disability and death and a huge economic burden throughout the world. Much of the morbidity associated with TBI is attributed to secondary brain injuries resulting in hypoxia and ischem...
Therapeutic hypothermia for the treatment of acute myocardial infarction-combined analysis of the RAPID MI-ICE and the CHILL-MI trials [0.03%]
治疗急性心肌梗死的治疗性低温-RAPID MI-ICE和CHILL-MI试验的综合分析
David Erlinge,Matthias Götberg,Marko Noc et al.
David Erlinge et al.
In the randomized rapid intravascular cooling in myocardial infarction as adjunctive to percutaneous coronary intervention (RAPID MI-ICE) and rapid endovascular catheter core cooling combined with cold saline as an adjunct to percutaneous c...
Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling [0.03%]
人和犬新皮质术中被动或主动局部冷却所达到的温度
Matthew D Smyth,Rowland H Han,Chester K Yarbrough et al.
Matthew D Smyth et al.
Focal cortical cooling inhibits seizures and prevents acquired epileptogenesis in rodents. To investigate the potential clinical utility of this treatment modality, we examined the thermal characteristics of canine and human brain undergoin...
Can Therapeutic Hypothermia Be Guided by Advanced Neuromonitoring in Neurocritical Care Patients? A Review [0.03%]
神经监测在神经重症患者治疗性低温中的指导作用？- 系统综述
Alois Josef Schiefecker,Ronny Beer,Gregor Broessner et al.
Alois Josef Schiefecker et al.
The impact of therapeutic hypothermia (TH) on long-term neurological outcome is still controversial. Data on the effects of TH on brain homeostasis are mostly derived from experimental research. Invasive multimodal neuromonitoring technique...
Successful use of therapeutic hypothermia after cardiac arrest due to amitriptyline and venlafaxine intoxication [0.03%]
中毒于阿米替林和文拉法辛的心脏骤停患者成功应用目标温度管理治疗
Terhi Kontio,Ari Salo,Teemu Kantola et al.
Terhi Kontio et al.
The prognosis of out-of-hospital cardiac arrest (OHCA) due to intoxication is dismal. Tricyclic antidepressants (TCAs) are widely used in the treatment of depression, but possess significant cardiotoxicity, and are one of the most common me...
Interpreting the results of the targeted temperature management trial in cardiac arrest [0.03%]
目标体温管理治疗心脏骤停患者的试验结果解读
Kees H Polderman,Joseph Varon
Kees H Polderman
The targeted temperature management (TTM) trial, which found that cooling to 33°C after witnessed cardiac arrest (CA) conferred no benefits compared with 36°C, has led to much debate in the hypothermia community. This article discusses wh...
Malin Rundgren,Stig Lyngbaek,Helle Fisker et al.
Malin Rundgren et al.
Background: Soluble urokinase plasminogen activator receptor (suPAR) is released in response to inflammatory stimuli, and plasma levels are associated with long-term outcomes. The ischemia/reperfusion injury caused by car...
Clinical Q & A: translating therapeutic temperature management from theory to practice [0.03%]
临床问答：如何将调控治疗体温的理念转化为实践
Mary Kay Bader
Mary Kay Bader
Carmelo Graffagnino,David Erlinge,Thomas Keeble et al.
Carmelo Graffagnino et al.
Patrick D Lyden,Fred Rincon,Dimitre Staykov et al.
Patrick D Lyden et al.