High-throughput profiling of tissue and tissue model microarrays: Combined transmitted light and 3-color fluorescence digital pathology [0.03%]
高通量组织和类组织微阵列谱分析：透射光与三色荧光数字化病理的结合
Michel Nederlof,Shigeo Watanabe,Bill Burnip et al.
Michel Nederlof et al.
For many years pathologists have used Hematoxylin and Eosin (H&E), single marker immunohistochemistry (IHC) and in situ hybridization with manual analysis by microscopy or at best simple digital imaging. There is a growing trend to update p...
Standardization of whole slide image morphologic assessment with definition of a new application: Digital slide dynamic morphometry [0.03%]
全切片图像形态学评估标准化及新应用：数字切片动态形态测量学
Giacomo Puppa,Mauro Risio,Kieran Sheahan et al.
Giacomo Puppa et al.
Background: In histopathology, the quantitative assessment of various morphologic features is based on methods originally conceived on specific areas observed through the microscope used. Failure to reproduce the same ref...
Jason Hipp,Jerome Cheng,Liron Pantanowitz et al.
Jason Hipp et al.
Introduction: The increasing availability of whole slide imaging (WSI) data sets (digital slides) from glass slides offers new opportunities for the development of computer-aided diagnostic (CAD) algorithms. With the all-...
Evaluation and optimization for liquid-based preparation cytology in whole slide imaging [0.03%]
液体基于细胞学制片在全玻片扫描中的评估与优化
Roy E Lee,David S McClintock,Nora M Laver et al.
Roy E Lee et al.
Background: Cytology poses different obstacles in whole slide imaging compared to surgical pathology slides. A single focal plane suffices for most of the latter, but cytology slides are thicker, potentially requiring mul...
High-definition hematoxylin and eosin staining in a transition to digital pathology [0.03%]
向数字病理学过渡中的高清苏木精和伊红染色法
Jamie D Martina,Christopher Simmons,Drazen M Jukic
Jamie D Martina
Introduction: A lot of attention has been generated in recent years by digital pathology and telepathology. Multiple reasons for and barriers to effective adoption are discussed in the current literature. Digital slides a...
Autofocus methods of whole slide imaging systems and the introduction of a second-generation independent dual sensor scanning method [0.03%]
全片扫描系统自动聚焦方法及其二代独立双传感器法的研究
Michael C Montalto,Richard R McKay,Robert J Filkins
Michael C Montalto
Accurate focusing is a critical challenge of whole slide imaging, primarily due to inherent tissue topography variability. Traditional line scanning and tile-based scanning systems are limited in their ability to acquire a high degree of fo...
Use of a laboratory information system driven tool for pre-signout quality assurance of random cytopathology reports [0.03%]
一种实验室信息系统驱动工具在细胞病理学常规报告签发前的质量控制中的应用
Sonal Kamat,Anil V Parwani,Walid E Khalbuss et al.
Sonal Kamat et al.
Background: Quality assurance (QA) programs in cytopathology laboratories in the USA currently primarily involve the review of Pap tests per clinical laboratory improvement amendments of 1988 federal regulations. A pre-si...
Use of mobile high-resolution device for remote frozen section evaluation of whole slide images [0.03%]
用于远程评估整个载玻片图像的移动高分辨率设备的应用
Joel Ramey,Kar Ming Fung,Lewis A Hassell
Joel Ramey
Introduction: With recent advances, it is now possible to view whole slide images (WSI) on mobile, high-resolution, viewing devices (MVD). This creates a new paradigm in which MVDs may be used for consultation and/or diag...
Oliver Lyttleton,Alexander Wright,Darren Treanor et al.
Oliver Lyttleton et al.
Background: The Tissue Microarray Data Exchange Specification (TMA DES) is an XML specification for encoding TMA experiment data. While TMA DES data is encoded in XML, the files that describe its syntax, structure, and se...
Implementation of whole slide imaging in surgical pathology: A value added approach [0.03%]
数字化病理在手术病理学中的应用——一种增加价值的方法
Mike Isaacs,Jochen K Lennerz,Stacey Yates et al.
Mike Isaacs et al.
Background: Whole slide imaging (WSI) makes it possible to capture images of an entire histological slide. WSI has established roles in surgical pathology, including support of off-site frozen section interpretation, prim...