Local isotropic phase symmetry measure for detection of beta cells and lymphocytes [0.03%]
局部等向相位对称性度量在β细胞和淋巴细胞检测中的应用研究
Manohar Kuse,Yi-Fang Wang,Vinay Kalasannavar et al.
Manohar Kuse et al.
Diabetes can be associated with a reduction in functional β cell mass, which must be restored if the disease is to be cured or progress is to be arrested. To study the cell count, it is also necessary to determine the number of nuclei with...
Graphical processing unit implementation of an integrated shape-based active contour: Application to digital pathology [0.03%]
图形处理器实现基于形状的集成活动轮廓法：在数字病理学中的应用
Sahirzeeshan Ali,Anant Madabhushi
Sahirzeeshan Ali
Commodity graphics hardware has become a cost-effective parallel platform to solve m any general computational problems. In medical imaging and more so in digital pathology, segmentation of multiple structures on high-resolution images, is ...
Andreas Kårsnäs,Anders L Dahl,Rasmus Larsen
Andreas Kårsnäs
Aims: The aim was to demonstrate a method for automated image analysis of immunohistochemically stained tissue samples for extracting features that correlate with patient disease. We address the problem of quantifying tum...
André Homeyer,Andrea Schenk,Uta Dahmen et al.
André Homeyer et al.
Histological image analysis methods often employ machine-learning classifiers in order to adapt to the huge variability of histological images. To train these classifiers, the user must select samples of the relevant image objects. In the f...
Biomechanical model-based deformable registration of MRI and histopathology for clinical prostatectomy [0.03%]
基于生物力学模型的临床前列腺切除术MRI与组织病理学图像配准方法研究
Navid Samavati,Deirdre M McGrath,Jenny Lee et al.
Navid Samavati et al.
A biomechanical model-based deformable image registration incorporating specimen-specific changes in material properties is optimized and evaluated for correlating histology of clinical prostatectomy specimens with in vivo MRI. In this meth...
Multi-field-of-view strategy for image-based outcome prediction of multi-parametric estrogen receptor-positive breast cancer histopathology: Comparison to Oncotype DX [0.03%]
基于图像的雌激素受体阳性乳腺癌多参数病理学结果预测的多重视野策略：与Oncotype DX相比
Ajay Basavanhally,Michael Feldman,Natalie Shih et al.
Ajay Basavanhally et al.
In this paper, we attempt to quantify the prognostic information embedded in multi-parametric histologic biopsy images to predict disease aggressiveness in estrogen receptor-positive (ER+) breast cancers (BCa). The novel methodological cont...
Yu Chen,Chia-Pin Liang,Yang Liu et al.
Yu Chen et al.
Pathology informatics encompasses digital imaging and related applications. Several specialized microscopy techniques have emerged which permit the acquisition of digital images ("optical biopsies") at high resolution. Coupled with fiber-op...
Gregory J Buffone
Gregory J Buffone
Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models [0.03%]
计算机辅助的成像算法可促进啮鼠肾功能衰竭模型中肾脏损伤的组织形态定量分析
Marcin Klapczynski,Gerard D Gagne,Sherry J Morgan et al.
Marcin Klapczynski et al.
Introduction: Surgical 5/6 nephrectomy and adenine-induced kidney failure in rats are frequently used models of progressive renal failure. In both models, rats develop significant morphological changes in the kidneys and ...
Estrogen receptor testing and 10-year mortality from breast cancer: A model for determining testing strategy [0.03%]
雌激素受体检测与乳腺癌10年死亡率的关系：确定检测策略的模型
Christopher Naugler
Christopher Naugler
Background: The use of adjuvant tamoxifen therapy in the treatment of estrogen receptor (ER) expressing breast carcinomas represents a major advance in personalized cancer treatment. Because there is no benefit (and indee...