The Influence of Racial, Socioeconomic, and Geographic Disparities in the Survival of Patients With Plasmablastic Lymphoma: A Population-Based Analysis From the Surveillance, Epidemiology, and End Results (SEER) Database (2000-2022) [0.03%]
基于SEER数据库(2000-2022年)的流行病学分析:种族、社会经济和地理差异对浆细胞淋巴瘤患者生存率的影响
Shahzaib Maqbool,Mohammad Ebad Ur Rehman,Muhammad Ibrahim et al.
Shahzaib Maqbool et al.
Background: Plasmablastic lymphoma (PBL) is a rare, aggressive subtype of large B-cell lymphoma with poor outcomes and limited population-level data available. Social determinants of health (SDOH) are known to impact outc...
Treatment in Clinical Trials Could Mitigate Socioeconomic and Racial Disparities in Acute Myeloid Leukemia [0.03%]
临床试验中的治疗可能有助于减轻急性髓系白血病的社会经济和种族差异
Mahesh Swaminathan,Hussein A Abbas,Michael Roth et al.
Mahesh Swaminathan et al.
Background: Disparities in acute myeloid leukemia (AML) outcomes due to nonbiological factors, including socioeconomic (SE) status and race/ethnicity, have been observed in population-based studies. However, inconsistent ...
Malignancy-Associated Hemophagocytic Lymphohistiocytosis: Clinical Characteristics, Treatment Patterns, and Survival Outcomes in a Tertiary Care Center Cohort [0.03%]
恶性相关的噬血细胞综合征的临床特点、治疗模式及预后特征:一家三级医疗机构的经验
Ricardo Kosch,Winfried Alsdorf,Paymon Ahmadi et al.
Ricardo Kosch et al.
Background: Malignancy-associated hemophagocytic lymphohistiocytosis (M-HLH) carries a poor prognosis and is often complicated by overlapping infection, cytopenias, organ failure, and progressive disease. ...
Validation of a QuPath-Based Artificial Intelligence Workflow for Plasma Cell Quantification on CD138 Immunohistochemistry in an Indian Hematopathology Cohort [0.03%]
基于QuPath的人工智能工作流程在印度血液病理队列CD138免疫组化浆细胞定量中的验证研究
Mohammed N Meera,Ankur Ahuja,Venkatesan Somasundaram et al.
Mohammed N Meera et al.
Introduction: Plasma cell percentage on CD138 immunohistochemistry of bone marrow trephine biopsies is fundamental to the diagnosis and risk stratification of plasma cell neoplasms, yet manual visual estimation is subject...
SOHO State of the Art Updates and Next Questions | Progress in Higher-Risk Myelodysplastic Syndromes [0.03%]
SOHO最新研究进展和未来方向|高危骨髓增生异常综合征的治疗进展
Carlotta Pazzi,Amy E DeZern
Carlotta Pazzi
Myelodysplastic syndromes (MDS) are clonal myeloid malignancies characterized by ineffective hematopoiesis and cytopenias, and possible risk of transformation to acute myeloid leukemia (AML). Higher-risk MDS (HR-MDS) carries significant mor...
Beyond Romidepsin: Novel Therapeutic Targets and Emerging Strategies for Relapsed and Refractory Peripheral T-Cell Lymphoma [0.03%]
来那度胺之后:复发/难治外周T细胞淋巴瘤的新型治疗靶点和新兴策略
Iemaan Rana,Jasmine Zain
Iemaan Rana
Peripheral T-cell lymphomas (PTCLs) represent heterogeneous aggressive non-Hodgkin lymphomas with dismal outcomes in the relapsed/refractory (R/R) setting. Following romidepsin's withdrawal from the R/R PTCL indication in 2021, the only FDA...
Myelodysplastic Syndrome With Autoimmune Disease: Clinical and Molecular Features and Survival Outcomes [0.03%]
伴自身免疫性疾病的骨髓衰竭综合征患者的临床及分子特征和生存分析
Yunsuk Choi,Eun-Ji Choi,Hyunkyung Park et al.
Yunsuk Choi et al.
Background: The myelodysplastic syndromes (MDS) frequently present with heterogeneous systemic inflammatory and autoimmune disease (AD). However, the pathobiology and prognostic impact of AD in MDS have not been fully elu...
The Prognostic Role of Interim [18F]FDG PET/CT in Diffuse Large B-Cell Lymphoma: An Updated Systematic Review and Meta-analysis [0.03%]
氟脱氧葡萄糖正电子发射断层扫描/X线计算机体层成像在弥漫大B细胞淋巴瘤中的预后作用:一项系统综述和meta分析的更新研究
Domenico Albano,Stephane Chauvie,Alessio Rizzo et al.
Domenico Albano et al.
The prognostic value of interim 18F-fluorodeoxyglucose positron emission tomography/computed tomography (iPET/CT) in diffuse large B-cell lymphoma (DLBCL) remains a subject of debate due to inconsistencies in timing and interpretation. This...
Real-World Evidence of Immunotherapy Sequencing in Multiple Myeloma: Durable Responses With BCMA-Targeting Bispecific Antibodies Following Prior GPRC5D-Targeting Therapy [0.03%]
靶向GPRC5D的疗法之后使用BCMA定向双特异性抗体治疗获得持久缓解的多发性骨髓瘤真实世界证据
Titouan Cazaubiel,Cyrille Touzeau,Laure Vincent et al.
Titouan Cazaubiel et al.
Background: T-cell-redirecting therapies (TCRTs), including bispecific antibodies (BsAbs) and chimeric antigen receptor-T-cell therapy targeting B-cell maturation antigen (BCMA) or G-protein-coupled receptor class C group...
Clinical and Biological Implications of TP53 Abnormalities in Relapsed/Refractory Multiple Myeloma: The DEDALO Study [0.03%]
TP53异常在复发难治性多发性骨髓瘤中的临床及生物学意义——DEDALO研究
Vittorio Montefusco,Anna Maria Cafro,Gloria Margiotta-Casaluci et al.
Vittorio Montefusco et al.
Background: Pomalidomide-daratumumab-dexamethasone (DPd) has been shown to be effective in lenalidomide-exposed patients with multiple myeloma (MM). We aimed to evaluate this combination in patients with del(17p), for who...