QbD-based Formulation Optimization and Characterization of Polymeric Nanoparticles of Cinacalcet Hydrochloride with Improved Biopharmaceutical Attributes [0.03%]
基于QbD的氢氯噻嗪多聚物纳米颗粒的制剂优化及改善药剂属性的定性分析研究
Debashish Ghose,Chinam Niranjan Patra,Bera Varaha Venkata Ravi Kumar et al.
Debashish Ghose et al.
Objectives: The aim of the present work was to prepare QbD enabled optimization, and to improve the oral bioavailability of freeze-dried polymeric nanoparticles of cinacalcet hydrochloride manufactured by nanoprecipitatio...
Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic [0.03%]
在门诊抗凝诊所接受华法林治疗的土耳其患者的知识测试的有效性评估
Meltem Türker,Mesut Sancar,Refik Demirtunç et al.
Meltem Türker et al.
Objectives: This study aimed to evaluate the validity and reliability of an oral anticoagulation knowledge (OAK) test in Turkish patients on warfarin therapy at an anticoagulant outpatient clinic. ...
Analytical Method Development and Validation for Simultaneous Determination of Simvastatin and Mupirocin Using Reverse-Phase High-pressure Liquid Chromatographic Method [0.03%]
simulteously测定西立伐他汀和莫匹罗星的反相高压液相色谱分析方法的研究与验证
Rupali Kale,Pratiksha Shete,Dattatray Doifode et al.
Rupali Kale et al.
Objectives: This study was aimed to develop and validate the use of reverse-phase high pressure liquid chromatographic method for the estimation of simvastatin (SIM) and mupirocin (MUP) simultaneously. ...
Phytochemical Study and Antioxidant Activities of the Water-Soluble Aerial Parts and Isolated Compounds of Thymus munbyanus subsp. ciliatus (Desf.) Greuter & Burdet [0.03%]
带叶小叶百里香水溶性部位的植物化学及抗氧化活性研究及其分离化合物的抗氧化活性研究
Massika Chaouche,İbrahim Demirtaş,Serkan Koldaş et al.
Massika Chaouche et al.
Objectives: The present study aimed to determine the phenolic compounds present in the water-soluble extracts of Thymus munbyanus subsp. ciliatus using high pressure liquid chromatography-time-of-flight mass spectrometry ...
Effects of Oleuropein on Epirubicin and Cyclophosphamide Combination Treatment in Rats [0.03%]
橄榄苦苷对表阿霉素和环磷酰胺联合用药大鼠的增效作用
Metin Deniz Karakoç,Selim Sekkin
Metin Deniz Karakoç
Objectives: Oleuropein is the main bioactive polyphenolic compound in olive leaves, olive, and olive oil. Its anticancer, antioxidant, and antiinflammatory effects have been proven through several in vitro and in vivo stu...
Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Estimation of Bictegravir, Emtricitabine, and Tenofovir Alafenamide Fumarate [0.03%]
一种同时测定比克替拉韦、恩曲他滨和特诺福韦艾拉酚胺富马酸酯的反相HPLC稳定性指示方法的开发与验证
Tanuja Attaluri,Ganapaty Seru,Satya Narayana Murthy Varanasi
Tanuja Attaluri
Objectives: The focal intent of the current research work is to develop and validate a novel and reliable stability-indicating reverse-phase high performance liquid chromatographic method for the simultaneous estimation o...
Effects of Bee Propolis on FBG, HbA1c, and Insulin Resistance in Healthy Volunteers [0.03%]
蜂胶对健康志愿者FBG、HbA1c和胰岛素抵抗的影响
Fawaz A Alassaf,Mahmood H M Jasim,Mohanad Alfahad et al.
Fawaz A Alassaf et al.
Objectives: Bee propolis is a natural substance that is used in traditional medicine due to its versatile pharmacological actions. This study evaluates whether short term use of bee propolis supplementation could have an ...
Effects of Pregabalin, Nimodipine, and Their Combination in the Inhibition of Status Epilepticus and the Prevention of Death in Mice [0.03%]
普瑞巴林、尼莫地平及其联用对小鼠癫痫持续状态的抑制及预防死亡的效果研究
Itefaq Qureshi,Azra Riaz,Rafeeq Khan et al.
Itefaq Qureshi et al.
Objectives: The current study aims to evaluate the combined antiepileptic effects of pregabalin (PGB) and nimodipine (NMD) in an acute seizure model of epilepsy in mice. ...
Preparation of Sterculia foetida-pullulan-Based Semi-interpenetrating Polymer Network Gastroretentive Microspheres of Amoxicillin Trihydrate and Optimization by Response Surface Methodology [0.03%]
响应面法优化万古梅三水合物载药胃漂浮微球的制备及其体内外相关性研究
Jayshri Hadke,Shagufta Khan
Jayshri Hadke
Objectives: In this study, a novel Sterculia foetida and pullulan-based semi-interpenetrating polymer network gastroretentive microsphere formulation was prepared using the emulsion crosslinking method and optimized by ce...
Jonghoon Kang,Luz Green,Kwajalen Hall
Jonghoon Kang