Discovery of Novel Pyruvate Kinase Inhibitors Against Leishmania major Among FDA Approved Drugs Through System Biology and Molecular Docking Approach [0.03%]
通过系统生物学和分子对接方法在FDA批准药物中发现抗利什曼原虫的新丙酮酸激酶抑制剂
Nasrin Amiri-Dashatan,Mostafa Rezaei-Tavirani,Mohammad Mehdi Ranjbar et al.
Nasrin Amiri-Dashatan et al.
Objectives: Leishmaniasis is one of the common forms of neglected parasitic diseases that cause a worldwide disease burden without any effective therapeutic strategy. Control of the disease currently relies on chemotherap...
Salacia pallescens Oliv. (Celastraceae) Scavenges Free Radicals and Inhibits Pro-inflammatory Mediators in Lipopolysaccharide-activated RAW Cells 264.7 Macrophages [0.03%]
萨拉西亞橄榄品种(Oliv.)（ celastraceae）清除自由基并抑制脂多糖活化RAW细胞264.7巨噬细胞中pro炎症介质
Oyindamola Olajumoke Abiodun,Tolulope Aderinola Oke,Faridah Oyinkansola Adeyemi et al.
Oyindamola Olajumoke Abiodun et al.
Objectives: Salacia pallescens has folkloric anti-inflammatory claims, with little scientific investigation. Hence, the antioxidant and anti-inflammatory effects along with phytochemical components of the plant were inves...
Sıdıka Öznur Sakınç,Emrah Bilgener
Sıdıka Öznur Sakınç
Objectives: Community pharmacies have financial difficulties due to reasons such as economic crises in recent years, increased competition, reimbursement cuts, decreasing drug prices and profit ratio, and increasing opera...
Neoteric Approach of Fluoxetine Laden Orodispersible Film for Non-compliant Pediatric Patients of Selective Mutism and Obsessive-compulsive Disorder [0.03%]
适用于选择性缄默症和强迫症不合规儿科患者的氟西汀载药可分散膜的新方法研究
Haseeb Anwar Dad,Asra Shanzeh Shabbir,Saman Ali et al.
Haseeb Anwar Dad et al.
Objectives: The objective of this research was to fabricate, characterize, and optimize fluoxetine laden orodispersible film (ODF), in enhancing dosage forms options for the pediatric population suffering from incapacitat...
Ethnopharmacobotanical Findings of Medicinal Plants in the Kızılcahamam District of Ankara, Turkey [0.03%]
土耳其安卡拉市Kızılcahamam地区药用植物的民族药用植物学调查结果
İlhan Gürbüz,Gizem Özatkan,Galip Akaydın et al.
İlhan Gürbüz et al.
Objectives: Folk medicines in Kızılcıhamam has not been investigated in detail so far. Thus, this study aimed to conduct a comprehensive investigation of folk medicine in the Kızılcahamam district. ...
The Potential Drug Interactions Between Multiple Sclerosis and COVID-19 Therapies [0.03%]
多发性硬化症和COVID-19治疗的潜在药物相互作用
Cansu Göncüoğlu,Aygin Bayraktar Ekincioğlu,Aslı Tuncer
Cansu Göncüoğlu
Electrochemical Detection of Linagliptin and its Interaction with DNA [0.03%]
利那呱汀的电化学检测及其与DNA相互作用的研究
Seda Nur Topkaya,Hüseyin Oğuzhan Kaya,Arif E Cetin
Seda Nur Topkaya
Objectives: Linagliptin (Lin) is a drug used in treatment of type 2 diabetes mellitus. In this study, the electrochemical detection of Lin and its interaction with DNA was analyzed for the first time using voltammetric me...
Cytotoxic Effects of Verbascoside on MCF-7 and MDA-MB-231 [0.03%]
Verbascoside对MCF-7和MDA-MB-231的细胞毒性作用
Hülya Şenol,Pınar Tulay,Mahmut Çerkez Ergören et al.
Hülya Şenol et al.
Objectives: Verbascoside, also known as acteoside/kusaginin, has attracted a great attention due to its pharmacological features. In this study, we aimed to determine the cytotoxic effects of pure verbascoside isolated fr...
Investigation of the Rheological Properties of Ointment Bases as a Justification of the Ointment Composition for Herpes Treatment [0.03%]
膏体基质流变性能的研究作为疱疹治疗的药膏配方依据
Tanya Ivko,Vita Hrytsenko,Lydmila Kienko et al.
Tanya Ivko et al.
Objectives: Combinatorial drugs are among the leading pharmacotherapeutic agents, including those used for the treatment of herpetic infections, which require complex treatment. We have developed a soft dosage form of oin...
Phytochemical Characterization of Phenolic Compounds by LC-MS/MS and Biological Activities of Ajuga reptans L., Ajuga salicifolia (L.) Schreber and Ajuga genevensis L. from Turkey [0.03%]
土耳其Ajuga reptans L.，Ajuga salicifolia（L.）Schreber和Ajuga genevensis L中的黄酮化合物的生物活性及LC-MS / MS特征分析
Gamze Göger,Yavuz Bülent Köse,Fatih Demirci et al.
Gamze Göger et al.
Objectives: In this study, it was aimed to characterize the phenolic contents of Ajuga reptans L., Ajuga salicifolia (L.) Schreber and Ajuga genevensis L. and to investigate their in vitro antioxidant and antimicrobial ac...