A Combination of Virgin Coconut Oil and Extra Virgin Olive Oil Elicits Superior Protection Against Doxorubicin Cardiotoxicity in Rats [0.03%]
virgin椰子油和extra virgin橄榄油对多柔比星心肌毒性的保护作用
Andi Ulfiana Utarı,Yulia Yusrini Djabir,Bogie Putra Palinggi
Andi Ulfiana Utarı
Objectives: The use of the chemotherapy agent doxorubicin (DOX) is associated with free radical formation that may lead to cardiotoxicity. Virgin coconut oil (VCO) and extra virgin olive oil (EVOO) are plant-based oil tha...
Protective Role of Diospyros lotus L. in Cisplatin-Induced Cardiotoxicity: Cardiac Damage and Oxidative Stress in Rats [0.03%]
柿子树(Diospyros lotus L.)对顺铂引起的心脏毒性的保护作用：大鼠心脏损伤和氧化应激研究
Neşe Başak Türkmen,Dilan Aşkın Özek,Aslı Taşlıdere et al.
Neşe Başak Türkmen et al.
Objectives: Cisplatin is a powerful chemotherapeutic drug that is used to treatment a wide variety of cancers. Despite clinical data demonstrating the cardiotoxic effect of cisplatin, few studies have been carried to impr...
Design, Development, Optimization and Evaluation of Ranolazine Extended Release Tablets [0.03%]
盐酸 ranolazine 缓释片的设计、开发、优化及评价
Raghavendra Kumar Gunda,Prasada Rao Manchineni,Dhachinamoorthi Duraiswamy et al.
Raghavendra Kumar Gunda et al.
Objectives: The objective of the current study was to develop an extended release (XR) tablet formulation for ranolazine using Eudragit L 100-55 and hydroxypropylmethylcellulose (HPMC) K100M in an appropriate composition....
Ameliorative Effect of Marine Macroalgae on Carbon Tetrachloride-Induced Hepatic Fibrosis and Associated Complications in Rats [0.03%]
海洋大型褐藻对四氯化碳致大鼠肝纤维化及其相关并发症改善作用的研究
Maria Azam,Khan Hira,Shamim A Qureshi et al.
Maria Azam et al.
Objectives: Liver fibrosis is one of the serious health concern around the globe. Persistent exposure to drugs, toxicants, and pathogens may induce liver fibrosis. Marine macroalgae are globally consumed because of nutrit...
Gurinder Singh
Gurinder Singh
Resveratrol is a natural compound (an antioxidant) and exhibits numerous therapeutic activities. From a pharmacokinetic perspective, it is unclear whether resveratrol targets the site of action after oral administration because of quick met...
Multi-drug Treatment for COVID-19-induced Acute Respiratory Distress Syndrome [0.03%]
用于治疗COVID-19引起的急性呼吸窘迫综合征的多药疗法
Masashi Ohe
Masashi Ohe
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), broke out in late 2019 to become a serious global threat to human health. In the absence of specific treatments for COVID-19, treat...
Molecular Docking Studies to Identify Promising Natural Inhibitors Targeting SARS-CoV-2 Nsp10-Nsp16 Protein Complex [0.03%]
针对SARS-CoV-2 Nsp10-Nsp16蛋白复合物的天然抑制剂分子对接研究
Anuradha Bhardwaj,Swati Sharma,Sandeep Kumar Singh
Anuradha Bhardwaj
Objectives: Unavailability of potential drugs/vaccines in the outbreak of the pandemic severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) have devastated the human population globally. Several druggable targets ...
The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization [0.03%]
芒柄花素纳米悬浮制剂的制备及体外表征研究
Afife Büşra Uğur Kaplan,Naile Öztürk,Meltem Çetin et al.
Afife Büşra Uğur Kaplan et al.
Objectives: Daidzein (DZ), a water-insoluble isoflavone, has many beneficial effects (anti-inflammatory, antioxidant, and anticancer effects, etc.) on human health. DZ has a very low oral bioavailability related to its ph...
Essential Oil Content, Antioxidative Characteristics and Enzyme Inhibitory Activity of Sideritis akmanii Aytaç, Ekici & Dönmez [0.03%]
Sideritis akmanii的精油成分、抗氧化特性及酶抑制活性
Laçine Aksoy,İsmail Güzey,Mürüvvet Düz
Laçine Aksoy
Objectives: Our research measures the essential oil analysis mineral substance profiles, total phenolic substance content, free radical scavenger properties, antioxidant capacity, and enzyme inhibitory activity of Siderit...
Determination of the Phototoxicity Potential of Commercially Available Tattoo Inks Using the 3T3-neutral Red Uptake Phototoxicity Test [0.03%]
采用3T3-中性红摄取法测定市售文身颜料的光毒性潜力
Elif Gözde Utku Türk,Ayse Tarbin Jannuzzi,Buket Alpertunga
Elif Gözde Utku Türk
Objectives: Tattooing is an ancient practice and its popularity has been increasing in the recent years. After tattooing, complications may occur related to compose tattoo inks. In this study, the phototoxicity potential ...