Fabrication and Evaluation of Matrix Type Novel Transdermal Patch Loaded with Tramadol Hydrochloride [0.03%]
载有盐酸特拉唑辛的矩阵型新型透皮贴剂的制备及评价
Shankhadip Nandi,Saptarshi Mondal
Shankhadip Nandi
Objectives: Transdermal drug delivery as a novel drug delivery system has become a major research interest to the scientists for its controlled drug release and improved patient compliance. This study was conducted to dev...
Nasotransmucosal Delivery of Curcumin-Loaded Mucoadhesive Microemulsions for Treating Inflammation-Related CNS Disorders [0.03%]
具有粘膜黏附性能的姜黄素类微乳液经鼻粘膜给药治疗与炎症相关的中枢神经系统疾病
Mukeshkumar Shamalbhai Patel,Snigdha Das Mandal,Surjyanarayan Mandal et al.
Mukeshkumar Shamalbhai Patel et al.
Objectives: This investigation was aimed at designing an effective mucoadhesive microemulsion system to accomplish higher brain uptake of curcumin through intranasal route. ...
Effects of Some Interferon-Related Proteins on Influenza A Viruse RNA Polymerase Activity [0.03%]
一些与干扰素相关的蛋白质对流感A病毒RNA聚合酶活性的影响
Elif Çağlayan,Kadir Turan
Elif Çağlayan
Objectives: Interferons (IFNs) are one of the most important components of innate immunity against viruses, especially those carrying the RNA genomes such as influenza viruses. Upon viral infection, the IFNs are rapidly s...
Potential Drug Interactions in Adults Living in Manaus: A Real-World Comparison of Two Databases, 2019 [0.03%]
2019年居住在玛瑙斯的成人用药相互作用的现实世界分析——两种数据库的比较研究
Tayanny Margarida Menezes Almeida Biase,Giulia Sartori Bruniéri,Marcus Tolentino Silva et al.
Tayanny Margarida Menezes Almeida Biase et al.
Objectives: Drug information systems are commonly used by professionals to assist in the identification of drug interactions and to ensure the safe use of medications. Real-world evidence about the comparison of different...
Stability Indicating RP-HPLC and Spectrophotometric Methods for Simultaneous Estimation of Sodium Benzoate and Cefdinir in the Presence of its Degradation Products-Application to Blank Subtraction Method [0.03%]
高效液相色谱法和紫外分光光度法同时测定苯甲酸钠和头孢丙烯及其降解产物的含量并应用于空白扣除法
Mahmoud Abdelfettah Mohamed,Mohamed El-Kassem Mohamed Hassouna
Mahmoud Abdelfettah Mohamed
Objectives: Empower 3 software is important in modeling, optimization, and reducing the time of manual calculation of related substance by subtracting the baseline of a blank chromatogram from the unknown sample automatic...
Studies on Almond Gum and Gelucire-Based Pellets Prepared by Extrusion and Spheronization for Sustained Release [0.03%]
用于控制释放的扁桃子胶和Gelucire基挤出素丸的研究
Ramesh Venkata Kanteti,Omar Sarheed,Hemant Yadav et al.
Ramesh Venkata Kanteti et al.
Objectives: The aim of the investigation was to prepare sustained release (SR) pellets of diltiazem hydrochloride employing almond gum and gelucire. The study was performed to explore the suitability of almond gum in the ...
Tableting Performance of Maize and Potato Starches Used in Combination as Binder/Disintegrant in Metronidazole Tablet Formulation [0.03%]
药用淀粉作为黏合剂和崩解剂在甲硝唑片剂中的应用性能研究
Yonni Eshovo Apeji,Rejoice Thomas Kaigama,Sani Hadi Ibrahim et al.
Yonni Eshovo Apeji et al.
Objectives: This study aimed to characterize the tableting performance of maize and potato starches, when used in combination either as a disintegrant or binder in solid dosage form development. ...
Dexamethasone and Citicoline Mitigate Cisplatin-Induced Peripheral Neuropathy: A Novel Experimental Study in Mice [0.03%]
新型实验性研究：德沙胞毒素和цитикотинinen减轻顺铂诱发的外周神经病变
Farid Masoud,Bohloul Habib-Asl,Mohammad Charkhpour et al.
Farid Masoud et al.
Objectives: Given the rising prevalence of cisplatin-induced peripheral neuropathy (CisIPN), investigations to alleviate its adverse effects are required. Oxidative stress and free radical development are essential pathwa...
Investigation of Selected Medicinal Plants for Their Anti-Obesity Properties [0.03%]
药用植物抗肥胖活性筛选研究进展
Sıla Özlem Şener,Eylül Cılız,Berre Nur Öztekin et al.
Sıla Özlem Şener et al.
Objectives: Obesity, which is a risk factor for diabetes, hypertension, cardiovascular diseases, and cancer, is caused serious health problems and economic costs on a global scale. Nowadays, pancreatic lipase inhibitors t...
Stability Indicating Assay Method for the Quantitative Determination of Olaparib in Bulk and Pharmaceutical Dosage Form [0.03%]
奥拉帕利原料和制剂的定量检测及其稳定性指示分析方法开发
Antima Chaudhary,Rajiv Tonk,Pankaj Dagur et al.
Antima Chaudhary et al.
Objectives: Olaparib is an orally active poly (ADP-ribose) PARP (polymerases) inhibitor known to destroy cancer cells with BRCA1 or BRCA2 deficiency. An authentic, fast, distinct, and reliable reverse phase-high performan...