Thermosensitive In situ Gelling System for Dermal Drug Delivery of Rutin [0.03%]
一种用于递送芦丁的皮肤给药的热敏原位凝胶系统
Sefa Gözcü,Kerem Heybet Polat
Sefa Gözcü
Objectives: Rutin has been broadly applied for treating several diseases due to its pharmacological activities. However, its low aqueous solubility limits its absorption and bioavailability. This research aims to increase...
Olea europaea L. Leaf Extract Attenuates Temozolomide-Induced Senescence-Associated Secretion Phenotype in Glioblastoma [0.03%]
Olea europaea L.叶提取物减轻替莫唑胺诱导的胶质母细胞瘤衰老相关分泌表型
Melis Erçelik,Berrin Tunca,Seçil Ak Aksoy et al.
Melis Erçelik et al.
Objectives: The purpose of this study was to investigate the effect of Olea europaea L. leaf extract (OLE) on senescence and senescence-associated secretory phenotype (SASP) caused by temozolomide (TMZ) in glioblastoma (G...
Ashwini K Bawankule,Amol A Tatode,Pranali S Patil et al.
Ashwini K Bawankule et al.
Paclitaxel (PTX) is used as a viable cancer medication in the chemotherapy of breast, ovarian, lung, bladder, neck, head, and esophageal tumors. The focus of this review is to survey various folate-targeting PTX-loaded nanopreparations in b...
Stability Evaluation of the Biosimilar Monoclonal Antibody Using Analytical Techniques [0.03%]
基于分析技术的生物仿制药单克隆抗体稳定性评价
Deniz Demirhan
Deniz Demirhan
Objectives: Determination of the drug substance (DS) and drug product (DP) stability is especially important for biosimilar monoclonal antibodies since it can affect the quality, efficacy, and safety of the drugs. The mai...
Development and Validation of SI/RS-UHPLC-PDA Method for Olmesartan Medoxomil and Metoprolol Succinate-Related Substance [0.03%]
奥美沙坦酯和酒石酸美托洛尔杂质的SI/RS-UHPLC-PDA法的研究与验证
Nirmal Thakker,Gajanan Shinde,Abhay Dharamsi et al.
Nirmal Thakker et al.
Objectives: Olmesartan medoxomil (OLM) and metoprolol succinate (MPS) in fixed-dose combination (FDC) tablet formulation prescribed extensively. Stability indicating (SI) method for impurities and related substance (RS) t...
Investigation of Antimicrobial Activity of Some Ethylparaben Hydrazide-Hydrazone Derivatives [0.03%]
乙基对羟基苯甲酸氢杂芳衍生物的抗菌活性研究
Ufuk İnce,M İhsan Han
Ufuk İnce
Objectives: The development of antimicrobial molecules discussed with considerable achievement over the past decades provided many classes of semisynthetic or synthetic compounds. Resistance to many antimicrobial agents r...
Resveratrol-Loaded Microsponge Gel for Wound Healing: In Vitro and In Vivo Characterization [0.03%]
负载白藜芦醇微海绵凝胶的伤口护理剂：体外及体内评价
Vinita Chandrakant Patole,Devyani Awari,Shilpa Chaudhari
Vinita Chandrakant Patole
Objectives: The study was aimed to formulate resveratrol (RSV) loaded microsponges to deliver drug at the wound site and incorporate it in the Moringa oleifera Lam. (Moringaceae) gel base to provide an appropriate moist e...
In Vitro Anti-Leishmanial Activity of Glucosinolate Fraction from Alyssum linifolium Steph. ex Willd (Brassicaceae) [0.03%]
欧亚独行菜（Brassicaceae）糖苷硫配体提取物的体外抗利什曼病活性
Fatemeh Mirzaee,Roghiyeh Faridnia,Mahdi Fakhar et al.
Fatemeh Mirzaee et al.
Objectives: The intracellular parasitic protozoan, Leishmania spp., causes several forms of diseases in humans. Cytotoxicity and emergence of new strains resistance to the current anti-leishmanial drugs have encouraged re...
Use of Herbal Tea/Herbal Preparations for Children with Symptoms of Viral Upper Respiratory Infections [0.03%]
儿童病毒性上呼吸道感染症状使用草药茶/草药制剂
Methiye Mancak Karakuş,Anıl Tapısız,Nazmi Mutlu Karakaş et al.
Methiye Mancak Karakuş et al.
Objectives: Respiratory tract infections (RTIs) are common in children. To treat the symptoms of simple health problems, individuals look for natural healing methods that can be easily prepared at home. The aim of this st...
Knowledge Assessment During the Medication Process Use by Older Patients on Clinical Routine: A Pilot Study [0.03%]
老年人临床用药过程中的知识评估：一项试点研究
Margarida Espírito-Santo,Tânia Nascimento,Ezequiel Pinto et al.
Margarida Espírito-Santo et al.
Objectives: The consumption of medicines has been increasing over the last decades. The lack of medication knowledge (MK) may affect the process of medication use and, consequently, may lead to negative health outcomes. T...