ATM Variants and Breast Cancer Risk in North Macedonia: Focus on the Regionally Enriched p.(Leu2492Arg) Variant [0.03%]
北马其顿的ATM变异和乳腺癌风险：重点关注区域富集的p.(Leu2492Arg)变异
Ivana Maleva Kostovska,Sanja Kiprijanovska,Predrag Noveski et al.
Ivana Maleva Kostovska et al.
Background: Germline pathogenic variants (PVs) in the ataxia-telangiectasia mutated (ATM) gene are established moderate-risk factors for breast cancer (BC), however, population-specific variant spectra and the clinical si...
Papillary Muscle Calcification as a Rare Cardiac Manifestation of β-Thalassemia-Related Pseudoxanthoma Elasticum-Like Syndrome [0.03%]
贝塔地中海贫血相关假黄瘤样弹性纤维营养不良的罕见心脏表现——乳头肌钙化
Fethi Gül,Damla Öztürk Efe
Fethi Gül
Anti-Thyroglobulin Antibodies as a Surrogate Tumor Marker for the Follow-Up of the Differentiated Thyroid Carcinoma: Clinical Implications and Pitfalls [0.03%]
抗甲状腺球蛋白抗体作为分化型甲状腺癌随访的肿瘤标志物的意义及陷阱
Esra Eraslan Aydemir,Feride Özkara Akkuş,Murat Faik Erdoğan
Esra Eraslan Aydemir
Antithyroglobulin antibodies (TgAb) are present in 10-25% of patients with differentiated thyroid cancer (DTC) and significantly affect the reliability of serum thyroglobulin (Tg) measurements during follow-up. Beyond causing assay interfer...
Enhancing the Therapeutic Index of Bioactive Compounds Through Novel Delivery Systems [0.03%]
通过新型递送系统提高生物活性化合物的治疗指数
Yeşim Hülya Uz,Suat Erdoğan
Yeşim Hülya Uz
SLC16A3-Induced Lactate Remodeling Drives Immune Evasion in Clear Cell Renal Cell Carcinoma via an Autocrine GPR81-ERK-c-MYC Feedback Loop [0.03%]
SLC16A3诱导的乳酸重塑通过自分泌GPR81-ERK-c-MYC反馈回路促进透明细胞肾细胞癌免疫逃逸
Shidong Zuo,Jinkai Dong,Yuhao Dong et al.
Shidong Zuo et al.
Background: Extensive studies have implicated glycolytic reprogramming and lactate accumulation in immune evasion. However, clustered regularly interspaced short palindromic repeats (CRISPR)-based in vivo screens systemat...
Machine Learning-Based Magnetocardiography Model Aids in Diagnosing Non-ST-Segment Elevation Acute Coronary Syndrome in Acute Chest Pain [0.03%]
基于机器学习的磁心电图模型有助于急性胸痛患者的非ST段抬高型急性冠脉综合征诊断
Junting Li,Yuheng Zhou,Ruizhe Wang et al.
Junting Li et al.
Background: Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a leading cause of acute chest pain in clinical practice. Magnetocardiography (MCG) is a non-invasive and rapid functional imaging technique with ...
Genotype-Phenotype Correlation in Tuberous Sclerosis Complex: Insights from Thirty-three Patients from North Macedonia [0.03%]
北马其顿33例结节性硬化症患者的基因型与表型相关性分析
Marija Gjorgjievska,Gjorgji Bozhinovski,Lejla Muaremoska Kanzoski et al.
Marija Gjorgjievska et al.
Additional PML and RARA Rearrangements Accompanying PML::RARA in a Case of Acute Promyelocytic Leukaemia with Myeloblast Morphology [0.03%]
急性早幼粒细胞白血病伴幼稚粒细胞性形态的额外PML和RARΑ重排伴随PML::RARΑ变异
Zhan Su,Wei Wang,Lingjie Sun et al.
Zhan Su et al.
Downregulation of IL16 Expression Induces Chemotherapeutic Drug Sensitivity via Increased Degradation of Mutant TP53 in Acute Myeloid Leukemia Cells [0.03%]
下调IL16表达通过增加急性髓系白血病细胞中突变TP53的降解来诱导化疗药物敏感性
Heng Zhang,Pengfei Qin,Anqiao Li et al.
Heng Zhang et al.
Background: Interleukin 16 (IL16) is a pleiotropic cytokine that does not belong to any interleukin family and functions as a CD4+ T-cell chemokine, a regulator of T-cell activation, and an inhibitor of human immunodefici...
Reduction in Albuminuria with Dapagliflozin Exhibits Substantial Interindividual Variability: A Real-World Study Utilizing a Big Data Approach [0.03%]
达格列净减少白蛋白尿的个体间差异显著：一项大数据真实世界研究
Jinfang Song,Yongru Zhuang,Chenling Wu et al.
Jinfang Song et al.
Background: Differences in the albuminuria-lowering effect of dapagliflozin and the associated factors require further exploration. Aims: ...