[Implication of MAP kinases in obesity-induced inflammation and insulin resistance] [0.03%]
MAPK在肥胖介导的炎症反应和胰岛素抵抗中的作用研究进展
Franck Ceppo,Jennifer Jager,Flavien Berthou et al.
Franck Ceppo et al.
Insulin resistance is often associated with obesity and is a major risk factor for development of type 2 diabetes as well as cardiovascular and hepatic diseases. Insulin resistance may also increase the incidence or the aggressiveness of so...
[Vitamin D and Alzheimer's disease: from an intriguing idea to a therapeutic option] [0.03%]
[维生素D与阿尔茨海默病：从一个有趣的想法到一种治疗选择]
Cédric Annweiler
Cédric Annweiler
Beyond the classically described regulation of calcium and bone metabolism, vitamin D is a neurosteroid hormone essential to neurophysiological function (regulation of neurotransmitters and neurotrophins) with anti-inflammatory and antioxid...
[Role of vitamin D in the physiopathology of neurodegenerative diseases] [0.03%]
维生素D在神经退行性疾病生理病理中的作用
Pascal Millet,Véréna Landel,Isabelle Virard et al.
Pascal Millet et al.
The involvement of vitamin D in brain function has been discovered in the past 25 years by epidemiological and fundamental studies. Research on neurodegenerative diseases and their animal or cellular models unveiled converging lines of evid...
François Féron,Tanguy Marqueste,John Bianco et al.
François Féron et al.
In 2014, a phase II randomised, double blind clinical trial assessing the efficacy of cholecalciferol (vitamin D3) in patients with a cervical trauma will be set up. This trial stems from previous studies showing that vitamin D supplementat...
[Metabolism and effects of vitamin D. Definition of vitamin D deficiency] [0.03%]
[维生素D的代谢及其作用和维生素D缺乏症的定义]
Jean-Claude Souberbielle
Jean-Claude Souberbielle
There is a growing interest for vitamin D in the medical and scientific community as well as in the public media as illustrated by a huge number of publications. Most experts claim that vitamin D deficiency/insufficiency is widespread with ...
[Classical actions of vitamin D: insights from human genetics and from mouse models on calcium and phosphate homeostasis] [0.03%]
经典维生素D作用及其遗传学和小鼠模型研究进展-聚焦钙磷代谢
Frédéric Jehan,Alexandru Voloc
Frédéric Jehan
At the beginning of the 20th century, the discovery of vitamin D by Sir EV McCollum allowed a better comprehension of its origin and its role, and made it possible to cure rickets, a largely prevalent disease at that time. The main role of ...
[Chemokines and attraction of myeloid cells in peripheral neuropathic pains] [0.03%]
化学趋化因子与外周神经病理性疼痛中髓系细胞的招募
Anaïs Sapienza,Annabelle Réaux-Le Goazigo,William Rostène et al.
Anaïs Sapienza et al.
Chronic neuropathic pain has become a real social issue, due to the difficulty of its treatment and by the major impairment to quality of life that it causes in every day behavior. Understanding neurobiological basis and pathophysiological ...
[Neurotrophins and pain] [0.03%]
神经营养因子与痛觉增强
Sophie Pezet
Sophie Pezet
Neurotrophins are a family of trophic factors well known for their effects on neuronal survival, growth and neuronal differentiation. During the last decade, a large literature has shown in humans and in animal models that nerve growth fact...
[Acid-Sensing Ion Channels (ASICs) in pain] [0.03%]
酸感受离子通道与痛觉 Transmission原文标题: Acid-Sensing Ion Channels (ASICs) in pain
Eric Lingueglia
Eric Lingueglia
The discovery of new drug targets represents a real opportunity for developing fresh strategies against pain. Ion channels are interesting targets because they are directly involved in the detection and the transmission of noxious stimuli b...
Roland Peyron
Roland Peyron
In this review, we summarize the contribution of functional imaging to the question of nociception in humans. In the beginning of the 90's, brain areas supposed to be involved in physiological pain processes essentially concerned the primar...