Adrien Rousseau,Catherine Tomasetto,Fabien Alpy
Adrien Rousseau
Eukaryotic epithelial cells form a sheet of contiguous cells, called epithelium, by means of the establishment of well-developed junctional complexes. These junctional complexes ensure the cell cohesion in the tissue and separate the plasma...
Alexandre Bolze
Alexandre Bolze
Isolated congenital asplenia is characterized by the absence of a spleen at birth without any other developmental defect. Isolated congenital asplenia is a rare and life-threatening disease that predisposes patients to severe bacterial infe...
[Is the biological clock central to the aging process? Studies in a non-human primate] [0.03%]
[生物钟是衰老过程的中心吗？一项非人类灵长类动物的研究]
Fabien Pifferi,Fabienne Aujard,Martine Perret
Fabien Pifferi
The ability of organisms to adapt to their environment during aging is altered. Age-related disorders in Human include disturbances of biological rhythms, especially sleep-wake rhythms alterations, and perturbations of body temperature and ...
Brigitte Grima
Brigitte Grima
Most living organisms possess a circadian clock (24 h period) which allows them to adapt to environmental conditions. Numerous studies in Drosophila allowed to discover various key clock genes, such as period and timeless. The powerful tool...
Etienne Challet
Etienne Challet
Circadian rhythmicity is an important component of physiological processes which provides them with a 24-hour temporal organization and adjustment to cyclical changes in the environment. Circadian rhythms are controlled by a network of endo...
Claude Gronfier
Claude Gronfier
Hormonal secretion, cognitive performance, motor activity, metabolic processes, the sleep wake cycle and, most recently shown, cell division and ADN repair show a 24 h rhythmicity that is driven by the circadian timing system (the biologica...
Frédérique Penault-Llorca
Frédérique Penault-Llorca
Diagnostic strategy of breast cancer has changed enormously during the last thirty years. To classical obligatory morphological data on the macroscopical and microscopical levels are now added imunocytochemistry, which is capable of detecti...
Laurent Angelo Arnoult
Laurent Angelo Arnoult
Genetic mutations are the main fuel of evolution. In each generation, they produce new variations, which may be sorted out by natural or sexual selection. Mutations are generated by chance; yet which are the mutations actually sorted out by...
[Role of tanycytes within the blood-hypothalamus interface] [0.03%]
视网膜母细胞瘤蛋白质在维持压力诱导的下丘脑血管周围空间扩大中的作用
Fanny Langlet
Fanny Langlet
Information exchanges between the brain and the periphery are key stages in the regulation of various physiological functions. The mediobasal hypothalamus, which ensures a large part of these functions, must be permanently informed about th...
[Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension] [0.03%]
口服肽基氨基酸氨转移酶A抑制剂可降低血压：治疗高血压的新策略
Catherine Llorens-Cortès
Catherine Llorens-Cortès
The hyperactivity of the brain renin-angiotensin system (RAS) has been implicated in the development and maintenance of hypertension in several types of experimental and genetic hypertension animal models. Among the main bioactive peptides ...