[Cognitive and brain development of memory from infancy to early adulthood] [0.03%]
从婴儿期到青春早期的记忆认知和脑发育
Fanny Dégeilh,Francis Eustache,Bérengère Guillery-Girard
Fanny Dégeilh
Cognitive and brain development are closely linked from infancy to adulthood. The purpose of this article is to review the current state of knowledge on behavioral and brain substrates of memory development. First, we will review cognitive ...
Alexandra Gros,Alexandra Veyrac,Serge Laroche
Alexandra Gros
A defining characteristic of the brain is its remarkable capacity to undergo activity-dependent functional and structural remodelling via mechanisms of plasticity that form the basis of our capacity to encode and retain memories. The prevai...
Mathieu Schaff,Christian Gachet,Pierre Henri Mangin
Mathieu Schaff
Anti-platelet agents such as aspirin, clopidogrel and antagonists of integrin αIIbβ3 allowed to efficiently reduce morbidity and mortality associated with arterial thrombosis. A major limit of these drugs is that they increase the risk of...
Max Goyffon,Frederick Saul,Grazyna Faure
Max Goyffon
Venomous function is investigated in relation to innate immune function in two cases selected from scorpion venom and serpent venom. In the first case, structural analysis of scorpion toxins and defensins reveals a close interrelation betwe...
William Rostene,Thierry Rayer
William Rostene
[Epigenetics and Nutrition: maternal nutrition impacts on placental development and health of offspring] [0.03%]
[表观遗传学与营养：母体营养对胎盘发育及子代健康的影响]
Polina E Panchenko,Marion Lemaire,Sara Fneich et al.
Polina E Panchenko et al.
The environment, defined broadly by all that is external to the individual, conditions the phenotype during development, particularly the susceptibility to develop non-communicable diseases. This notion, called Developmental Origins of Heal...
Pierre Boyer,Debbie Montjean,Cendrine Siraudin et al.
Pierre Boyer et al.
Ovocyte vitrification was finally authorized by the new law voted in July 2011 upon the revision of the French bioethics law. Expected for 30 years, cryopreservation of female gametes had a major impact on Assisted Reproductive Technologies...
[Towards a vaccine against HIV: antibodies raised by a gp41 peptide neutralize the virus and inhibit pathogenesis] [0.03%]
一种针对HIV的疫苗的研究：gp41肽诱导产生的抗体可以中和病毒并抑制病理变化
Vincent Vieillard,Patrice Debré
Vincent Vieillard
In spite of numerous attempts, only one vaccine candidate showed a potentiality to prevent HIV infection. Such capacity, unfortunately partial, was due to the activity of specific antibodies, indicating the importance of humoral responses. ...
[Stimulating Type I interferon response with small molecules: revival of an old idea] [0.03%]
用小分子刺激I类干扰素反应：重拾一个老观点
Samira Khiar,Nicolas Pietrancosta,Pierre-Olivier Vidalain
Samira Khiar
Type I interferons play a central role in the establishment of an innate immune response against viral infections and tumor cells. Shortly after their discovery in 1957, several groups have looked for small molecules capable of inducing the...
[Plasmacytoid dendritic cells: the novel Eldorado for antiviral therapy?] [0.03%]
浆细胞样树突状细胞：抗病毒治疗的新机遇？
Nikaïa Smith,Jean-Philippe Herbeuval
Nikaïa Smith
Plasmacytoid dendritic cells (pDCs) represent the first line of host defense against viruses and are an essential link between innate and adaptive immunity. The antiviral factor IFN-α is massively produced by pDCs in response to HIV infect...