[In vitro generation of blood red cells from stem cells: a sketch of the future] [0.03%]
[体外由干细胞生成红细胞:未来前景综述]
Christelle Mazurier,Luc Douay
Christelle Mazurier
Human adult pluripotent stem cells, stem cells of embryonic origin and induced pluripotent stem cells (iPS) provide cellular sources for new promising regenerative medicine approaches. Because these cells can be patient-specific, they allow...
Caroline Sansac,Said Assou,Julien Bouckenheimer et al.
Caroline Sansac et al.
Induced pluripotent stem cells (iPSCs) are obtained by reprogramming differentiated cells through forced expression of four embryonic transcription factors. The discovery of this technology, able to transform a differentiated cell into a pl...
[From dualism to multiplicity: seeing BCL-2 family proteins and cell death with new eyes] [0.03%]
从二元对立到多元并存——用新视角看待Bcl-2蛋白家族和细胞死亡
Abdel Aouacheria
Abdel Aouacheria
The concept of cell death has many links to the concept of death itself, defined as the opposite of life. Achievements obtained through research on apoptosis have apparently allowed us to transcend this Manichean view. Death is no longer ou...
[Nutrient sensing by the gastro-intestinal nervous system and control of energy homeostasis] [0.03%]
胃肠神经系统的感觉与能量平衡的调控
Mithieux Gilles
Mithieux Gilles
The gastrointestinal nerves are crucial in the sensing of nutrients and hormones and its translation in terms of control of food intake. Major macronutrients like glucose and proteins are sensed by the extrinsic nerves located around the po...
[Adaptation to the availability of essential amino-acids: role of GCN2/eIF2α/ATF4 pathway] [0.03%]
[适应必需氨基酸的可用性:GCN2/eIF2α/ATF4途径的作用]
Pierre Fafournoux,Julien Averous,Alain Bruhat et al.
Pierre Fafournoux et al.
In mammals, metabolic adaptations are required to overcome nutritional deprivation in amino-acids/proteins as well as episodes of malnutrition. GCN2 protein kinase, which phosphorylates the α subunit of the translation initiation factor eI...
Christophe Magnan,Serge Luquet
Christophe Magnan
Fatty acid (FA)-sensitive neurons are present in the brain, especially the hypothalamus, and play a key role in the neural control of energy and glucose homeostasis including feeding behavior, insulin secretion and action. Subpopulations of...
[Role of the mTOR pathway in the central regulation of energy balance] [0.03%]
[mTOR信号通路在能量平衡中枢调节中的作用]
Magalie Haissaguerre,Daniela Cota
Magalie Haissaguerre
The pathway of the mammalian (or mechanistic) target of rapamycin kinase (mTOR) responds to different signals such as nutrients and hormones and regulates many cellular functions as the synthesis of proteins and lipids, mitochondrial activi...
Fabienne Collette,Lucie Angel
Fabienne Collette
The existence of processes common to memory systems and executive functioning was evidenced by studies in the domain of cerebral neuroimaging, individual differences (mainly in normal aging) and, to a lesser extent, neuropsychology. Executi...
[Neuroscience and collective memory: memory schemas linking brain, societies and cultures] [0.03%]
[神经科学与集体记忆:联结大脑、社会和文化的记忆模式]
Nicolas Legrand,Pierre Gagnepain,Denis Peschanski et al.
Nicolas Legrand et al.
During the last two decades, the effect of intersubjective relationships on cognition has been an emerging topic in cognitive neurosciences leading through a so-called "social turn" to the formation of new domains integrating society and cu...
[The role of sleep in memory consolidation: effects of age and Alzheimer's disease] [0.03%]
睡眠在记忆巩固中的作用:年龄和阿尔茨海默病的影响
Carine Malle,Francis Eustache,Géraldine Rauchs
Carine Malle
Sleep favors memory consolidation. Studies conducted in recent years allowed to reveal the neurobiological underpinnings underlying the beneficial effect of sleep on memory. They also have led to the proposal of two theoretical models: the ...