[Two-pore-domain potassium channels and molecular mechanisms underlying migraine] [0.03%]
[二孔钾通道与偏头痛的分子机制]
Perrine Royal,Pablo Ávalos Prado,Brigitte Wdziekonski et al.
Perrine Royal et al.
Migraine is a common, disabling neurological disorder with genetic, environmental and hormonal components and a prevalence estimated at ∼15%. Migraine episodes are notably related, among several factors, to electric hyperexcitability in se...
Laurence Bourgeais-Rambur,Laurianne Beynac,Luis Villanueva
Laurence Bourgeais-Rambur
A large body of clinical and pre-clinical evidence has shown complex interactions between bottom-up and top-down mechanisms that are essential for the discrimination of noxious information and pain perception. These endogenous systems, main...
Caroline Roos
Caroline Roos
Burden of disease study ranks headache disorders as the second leading cause of years lived with disability worldwide. Migraine has an estimated prevalence of 10 to 14% and is therefore the most common neurological pathology. It concerns yo...
Natacha Roux,Pauline Salis,Vincent Laudet
Natacha Roux
Life history transitions are critical for many animal species and often correspond to concomitant developmental and ecological shifts. However, to date, little is known on how internal and external cues act together during these events. The...
[Thyroid disruptors and their consequences on brain development and behavior] [0.03%]
甲状腺干扰物及其对脑发育和行为的影响
Jean-Baptiste Fini,Barbara Demeneix
Jean-Baptiste Fini
An increase in the prevalence of many diseases affecting the nervous system in both children and adults has been reported. Some of these diseases are related to endocrine dysfunction, notably of the thyroid axis. Examples in children are at...
Sylvie Remaud,Barbara Demeneix
Sylvie Remaud
Thyroid hormones (THs) are vital for vertebrate brain function throughout life, from early development to ageing. Epidemiological studies show an adequate supply of maternal TH during pregnancy to be necessary for normal brain development, ...
[Epidemiology of congenital hypothyroidism in France: recent data] [0.03%]
[法国先天性甲状腺功能减退症的流行病学：最新数据]
Juliane Léger
Juliane Léger
Congenital hypothyroidism (CH) is the leading cause of preventable mental retardation. It is mainly due to thyroid dysgenesis or dyshormonogenesis with normally located gland, and detected at birth in developed countries, by mass biochemica...
Frédéric Simard
Frédéric Simard
Vector control is a cornerstone of vector-borne infectious disease control, a group of emerging and re-emerging diseases of major public health concern at a global scale. The history and evolution of mosquito disease vectors control, mainly...
Katy Heu,Mathilde Gendrin
Katy Heu
Mosquitoes (Diptera: Culicidae) are found worldwide. Around 100 among 3500 mosquito species are known to be vectors of parasites and viruses, responsible for infectious diseases including malaria and dengue. Mosquitoes host diverse microbia...
Nathalie Boulanger
Nathalie Boulanger
Ticks are the most important vectors of pathogens in human and veterinary medicine. These strictly haematophagous acarines produce a saliva containing a variety of bioactive molecules affecting host pharmacology and immunity. This process i...