Nicolas Froger
Nicolas Froger
Discovered in the eighties by Pr Baulieu and colleagues, neurosteroids are a class of neuroactive brain-born steroids, which comprises the steroid hormones, their biosynthesis precursors and their metabolites. They can act through genomic a...
Rémi Corne,Raymond Mongeau
Rémi Corne
Psychedelic drugs, often referred to as hallucinogens, are quite distinct from other classes of psychotropic drugs. Although the subjective and behavioral effects they induce are quite dramatic, they possess little addictive potential when ...
[PET imaging for better understanding of normal and pathological neurotransmission] [0.03%]
[positron发射断层扫描成像技术有助于更好地了解正常和异常的神经传导]
Luc Zimmer
Luc Zimmer
Positron emission tomography imaging is still an expanding field of preclinical and clinical investigations exploring the brain and its normal and pathological functions. In addition to technological improvements in PET scanners, the availa...
[Narcolepsy: From the discovery of a wake promoting peptide to autoimmune T cell biology and molecular mimicry with flu epitopes] [0.03%]
[发作性睡眠病:从觉醒促进肽的发现到自身免疫T细胞生物学与流感表位分子模拟性研究]
Jean-Marie Ravel,Emmanuel J M Mignot
Jean-Marie Ravel
Narcolepsy-cataplexy was first described in the late 19th century in Germany and France. Prevalence was established to be 0.05 % and a canine model was discovered in the 1970s. In 1983, a Japanese study found that all patients carried HLA-D...
[Michel Jouvet, from the discovery of paradoxical sleep and muscle atonia to the role of neuropeptides] [0.03%]
从发现异相睡眠和骨骼肌麻痹到神经肽的作用:米谢尔乔维的学术生涯回顾与前瞻
Pierre-Hervé Luppi
Pierre-Hervé Luppi
This article focuses on the contributions made by Michel Jouvet about the neurons responsible for generating the muscle atonia of paradoxical sleep (REM sleep). He was the first to describe the neurons responsible for muscle atonia during p...
Bernard Kerdelhué [0.03%]
贝尔纳·科尔德吕埃
William Rostène
William Rostène
Pierre Godeau [0.03%]
皮埃尔·戈杜
Claude Jaffiol
Claude Jaffiol
Georges David [0.03%]
乔治·戴维
Pierre Jouannet
Pierre Jouannet
Jacques-Paul Borel [0.03%]
雅克-保罗·博雷尔
François Xavier Maquart
François Xavier Maquart
Dominique Valade
Dominique Valade
The current treatment of migraine attacks is triptans and NSAIDs, but the calcitonin gene-related peptide (CGRP) has emerged as a key neuropeptide target for migraine therapy. Despite an off target class effect on liver enzymes, two CGRP re...